Loss and dysfunction of Vδ2⁺ γδ T cells are associated with clinical tolerance to malaria.
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Impact of In Utero Exposure to Malaria on Fetal T Cell Immunity.Synergistic effect of IL-12 and IL-18 induces TIM3 regulation of γδ T cell function and decreases the risk of clinical malaria in children living in Papua New GuineaFCRL5 Delineates Functionally Impaired Memory B Cells Associated with Plasmodium falciparum Exposure.Decline of FoxP3+ Regulatory CD4 T Cells in Peripheral Blood of Children Heavily Exposed to MalariaPhosphoantigen Burst upon Plasmodium falciparum Schizont Rupture Can Distantly Activate Vγ9Vδ2 T Cells.A Novel Model of Asymptomatic Plasmodium Parasitemia That Recapitulates Elements of the Human Immune Response to Chronic Infection.The effect of declining exposure on T cell-mediated immunity to Plasmodium falciparum - an epidemiological "natural experiment".Frequent Malaria Drives Progressive Vδ2 T-Cell Loss, Dysfunction, and CD16 Up-regulation During Early Childhood.Transcriptomic evidence for modulation of host inflammatory responses during febrile Plasmodium falciparum malaria.Patterns of inflammatory responses and parasite tolerance vary with malaria transmission intensity.High pathogen burden in childhood promotes the development of unconventional innate-like CD8+ T cells.Examining cellular immune responses to inform development of a blood-stage malaria vaccine.Dysfunctional γδ T cells: a contributing factor for clinical tolerance to malaria?Preferentially expanding Vγ1+ γδ T cells are associated with protective immunity against Plasmodium infection in mice.A Unique Subset of γδ T Cells Expands and Produces IL-10 in Patients with Naturally Acquired Immunity against Falciparum Malaria.Vδ2+ T cell response to malaria correlates with protection from infection but is attenuated with repeated exposure.Longitudinal study of changes in γδ T cells and CD4+ T cells upon asymptomatic malaria infection in Indonesian children.γδ T cells and immunity to human malaria in endemic regions.TCR signal strength controls thymic differentiation of discrete proinflammatory γδ T cell subsets.The Development of Plasmodium falciparum-Specific IL10 CD4 T Cells and Protection from Malaria in Children in an Area of High Malaria Transmission.Evaluating anti-disease immunity to malaria and implications for vaccine design.Both inflammatory and regulatory cytokine responses to malaria are blunted with increasing age in highly exposed children.γδ T Cells Are Required for the Induction of Sterile Immunity during Irradiated Sporozoite Vaccinations.Atypical activation of dendritic cells by Plasmodium falciparum.Transcriptomic Studies of Malaria: a Paradigm for Investigation of Systemic Host-Pathogen InteractionsProtective Role of T Cells in Different Pathogen Infections and Its Potential Clinical Applicationγδ T Cells in Antimalarial Immunity: New Insights Into Their Diverse Functions in Protection and Tolerance
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P2860
Loss and dysfunction of Vδ2⁺ γδ T cells are associated with clinical tolerance to malaria.
description
2014 nî lūn-bûn
@nan
2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Loss and dysfunction of Vδ2⁺ γ ...... clinical tolerance to malaria.
@ast
Loss and dysfunction of Vδ2⁺ γ ...... clinical tolerance to malaria.
@en
Loss and dysfunction of Vδ2⁺ γ ...... clinical tolerance to malaria.
@nl
type
label
Loss and dysfunction of Vδ2⁺ γ ...... clinical tolerance to malaria.
@ast
Loss and dysfunction of Vδ2⁺ γ ...... clinical tolerance to malaria.
@en
Loss and dysfunction of Vδ2⁺ γ ...... clinical tolerance to malaria.
@nl
prefLabel
Loss and dysfunction of Vδ2⁺ γ ...... clinical tolerance to malaria.
@ast
Loss and dysfunction of Vδ2⁺ γ ...... clinical tolerance to malaria.
@en
Loss and dysfunction of Vδ2⁺ γ ...... clinical tolerance to malaria.
@nl
P2093
P2860
P50
P1476
Loss and dysfunction of Vδ2⁺ γ ...... clinical tolerance to malaria.
@en
P2093
Charlie C Kim
Felistas Nankya
Ijeoma Eccles-James
Katherine Bowen
Margaret E Feeney
Mary K Muhindo
Prasanna Jagannathan
P2860
P304
P356
10.1126/SCITRANSLMED.3009793
P407
P577
2014-08-01T00:00:00Z