Antiatherosclerotic and renoprotective effects of ebselen in the diabetic apolipoprotein E/GPx1-double knockout mouse
about
Targeting Mitochondria and Reactive Oxygen Species-Driven Pathogenesis in Diabetic NephropathyParadoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health ImplicationsCombined NOX1/4 inhibition with GKT137831 in mice provides dose-dependent reno- and atheroprotection even in established micro- and macrovascular disease.The modified selenenyl amide, M-hydroxy ebselen, attenuates diabetic nephropathy and diabetes-associated atherosclerosis in ApoE/GPx1 double knockout miceNADPH oxidases, reactive oxygen species, and the kidney: friend and foe.Noninvasive MRI monitoring of the effect of interventions on endothelial permeability in murine atherosclerosis using an albumin-binding contrast agent.Ebselen induces reactive oxygen species (ROS)-mediated cytotoxicity in Saccharomyces cerevisiae with inhibition of glutamate dehydrogenase being a target.Targeting endothelial dysfunction in vascular complications associated with diabetes.What are new avenues for renal protection, in addition to RAAS inhibition?Novel pathways and therapies in experimental diabetic atherosclerosis.Combating oxidative stress in diabetic complications with Nrf2 activators: how much is too much?Ebselen, a promising antioxidant drug: mechanisms of action and targets of biological pathways.Are reactive oxygen species still the basis for diabetic complications?Responses to reductive stress in the cardiovascular system.Induction of apoptosis in human multiple myeloma cell lines by ebselen via enhancing the endogenous reactive oxygen species production.Late-intervention study with ebselen in an experimental model of type 1 diabetic nephropathy.Nanoporous Metal-Phenolic Particles as Ultrasound Imaging Probes for Hydrogen Peroxide.Does lack of glutathione peroxidase 1 gene expression exacerbate lung injury induced by neonatal hyperoxia in mice?Discovery of ebselen as an inhibitor of Cryptosporidium parvum glucose-6-phosphate isomerase (CpGPI) by high-throughput screening of existing drugs.Lipoxins Regulate the Early Growth Response-1 Network and Reverse Diabetic Kidney Disease.Repurposing ebselen for decolonization of vancomycin-resistant enterococci (VRE).
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Antiatherosclerotic and renoprotective effects of ebselen in the diabetic apolipoprotein E/GPx1-double knockout mouse
description
2010 nî lūn-bûn
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2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
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2010年論文
@zh-mo
2010年論文
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2010年论文
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name
Antiatherosclerotic and renopr ...... n E/GPx1-double knockout mouse
@ast
Antiatherosclerotic and renopr ...... n E/GPx1-double knockout mouse
@en
Antiatherosclerotic and renopr ...... n E/GPx1-double knockout mouse
@nl
type
label
Antiatherosclerotic and renopr ...... n E/GPx1-double knockout mouse
@ast
Antiatherosclerotic and renopr ...... n E/GPx1-double knockout mouse
@en
Antiatherosclerotic and renopr ...... n E/GPx1-double knockout mouse
@nl
prefLabel
Antiatherosclerotic and renopr ...... n E/GPx1-double knockout mouse
@ast
Antiatherosclerotic and renopr ...... n E/GPx1-double knockout mouse
@en
Antiatherosclerotic and renopr ...... n E/GPx1-double knockout mouse
@nl
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Antiatherosclerotic and renopr ...... n E/GPx1-double knockout mouse
@en
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Derek Y C Yuen
Franklin Rosenfeldt
Josefa Pete
Judy B de Haan
Karin A Jandeleit-Dahm
Mark E Cooper
Melinda T Coughlan
Merlin C Thomas
Nada Stefanovic
Phyllis Chew
P2860
P304
P356
10.2337/DB10-0195
P407
P577
2010-09-07T00:00:00Z