Suppression of Aurora-A oncogenic potential by c-Myc downregulation
about
Aurora-A signaling is activated in advanced stage of squamous cell carcinoma of head and neck cancer and requires osteopontin to stimulate invasive behavior.P21-activated kinase 7 mediates cisplatin-resistance of esophageal squamous carcinoma cells with Aurora-A overexpression.Aurora A is differentially expressed in gliomas, is associated with patient survival in glioblastoma and is a potential chemotherapeutic target in gliomas.Aurora-A inhibition offers a novel therapy effective against intracranial glioblastoma.Myc, Aurora Kinase A, and mutant p53(R172H) co-operate in a mouse model of metastatic skin carcinoma.Aurora A kinase (AURKA) in normal and pathological cell division.RNA interference targeting Aurora-A sensitizes glioblastoma cells to temozolomide chemotherapy.Aurora-A: a potential DNA repair modulator.MYC in pancreatic cancer: novel mechanistic insights and their translation into therapeutic strategies.Aurora-A Kinase: A Potent Oncogene and Target for Cancer Therapy.Differential expression of aurora-A kinase in T-cell lymphomas.Alisertib demonstrates significant antitumor activity in bevacizumab resistant, patient derived orthotopic models of glioblastoma.APIO-EE-9 is a novel Aurora A and B antagonist that suppresses esophageal cancer growth in a PDX mouse model.The selective Aurora-A kinase inhibitor MLN8237 (alisertib) potently inhibits proliferation of glioblastoma neurosphere tumor stem-like cells and potentiates the effects of temozolomide and ionizing radiation.Mantle cell lymphoma harboring Burkitt's-like translocations presents differential expression of aurora kinase genes compared with others 8q abnormalities.
P2860
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P2860
Suppression of Aurora-A oncogenic potential by c-Myc downregulation
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Suppression of Aurora-A oncogenic potential by c-Myc downregulation
@ast
Suppression of Aurora-A oncogenic potential by c-Myc downregulation
@en
Suppression of Aurora-A oncogenic potential by c-Myc downregulation
@nl
type
label
Suppression of Aurora-A oncogenic potential by c-Myc downregulation
@ast
Suppression of Aurora-A oncogenic potential by c-Myc downregulation
@en
Suppression of Aurora-A oncogenic potential by c-Myc downregulation
@nl
prefLabel
Suppression of Aurora-A oncogenic potential by c-Myc downregulation
@ast
Suppression of Aurora-A oncogenic potential by c-Myc downregulation
@en
Suppression of Aurora-A oncogenic potential by c-Myc downregulation
@nl
P2093
P2860
P1476
Suppression of Aurora-A oncogenic potential by c-Myc downregulation
@en
P2093
Hongxia Zhu
Jingfeng Bai
Lanping Quan
Ningzhi Xu
Shangbin Yang
Shuang Yan
Xiaobo Zhou
P2860
P2888
P304
P356
10.3858/EMM.2010.42.11.077
P50
P577
2010-11-01T00:00:00Z
P5875
P6179
1002950520