GC skew at the 5' and 3' ends of human genes links R-loop formation to epigenetic regulation and transcription termination
about
Out of balance: R-loops in human diseaseFragile X-associated tremor/ataxia syndrome.Breaking bad: R-loops and genome integrityEffects of DNA supercoiling on chromatin architectureIntegrator: surprisingly diverse functions in gene expressionReplication stress in Mammalian cells and its consequences for mitosisGenetic instability in budding and fission yeast-sources and mechanismsTranscription-associated R-loop formation across the human FMR1 CGG-repeat regionThe deletion of rnhB in Mycobacterium smegmatis does not affect the level of RNase HII substrates or influence genome stabilityEvolution of the Antisense Overlap between Genes for Thyroid Hormone Receptor and Rev-erbα and Characterization of an Exonic G-Rich Element That Regulates Splicing of TRα2 mRNABiological Processes Discovered by High-Throughput Sequencing.Production of Extrachromosomal MicroDNAs Is Linked to Mismatch Repair Pathways and Transcriptional ActivityS1-DRIP-seq identifies high expression and polyA tracts as major contributors to R-loop formation.StochHMM: a flexible hidden Markov model tool and C++ library.Complexity of genetic mechanisms conferring nonuniformity of recombination in maizeMechanisms of genome instability induced by RNA-processing defects.A double-edged sword: R loops as threats to genome integrity and powerful regulators of gene expressionVariable escape from X-chromosome inactivation: identifying factors that tip the scales towards expressionGenome-wide profiling of yeast DNA:RNA hybrid prone sites with DRIP-chipGenome-wide distribution of RNA-DNA hybrids identifies RNase H targets in tRNA genes, retrotransposons and mitochondriaRescue from replication stress during mitosis.Transcription-coupled nucleotide excision repair factors promote R-loop-induced genome instabilityR-loops associated with triplet repeat expansions promote gene silencing in Friedreich ataxia and fragile X syndrome.A genome-wide analysis of Cas9 binding specificity using ChIP-seq and targeted sequence capture.RNA processing factors Swd2.2 and Sen1 antagonize RNA Pol III-dependent transcription and the localization of condensin at Pol III genesHead-to-head antisense transcription and R-loop formation promotes transcriptional activation.RNase HI Is Essential for Survival of Mycobacterium smegmatis.Complexities due to single-stranded RNA during antibody detection of genomic rna:dna hybrids.The Fanconi Anemia Pathway Protects Genome Integrity from R-loops.Dynamic Effects of Topoisomerase I Inhibition on R-Loops and Short Transcripts at Active PromotersRegulated Formation of lncRNA-DNA Hybrids Enables Faster Transcriptional Induction and Environmental Adaptation.Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi-Goutières syndrome.XRN2 Links Transcription Termination to DNA Damage and Replication Stress.GC skew defines distinct RNA polymerase pause sites in CpG island promoters.RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships.R loops regulate promoter-proximal chromatin architecture and cellular differentiation.The monoclonal S9.6 antibody exhibits highly variable binding affinities towards different R-loop sequences.Nascent RNA folding mitigates transcription-associated mutagenesisThe spliceosome-associated protein Nrl1 suppresses homologous recombination-dependent R-loop formation in fission yeast.GC skew is a conserved property of unmethylated CpG island promoters across vertebrates
P2860
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P2860
GC skew at the 5' and 3' ends of human genes links R-loop formation to epigenetic regulation and transcription termination
description
2013 nî lūn-bûn
@nan
2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
GC skew at the 5' and 3' ends ...... and transcription termination
@ast
GC skew at the 5' and 3' ends ...... and transcription termination
@en
GC skew at the 5' and 3' ends ...... and transcription termination
@nl
type
label
GC skew at the 5' and 3' ends ...... and transcription termination
@ast
GC skew at the 5' and 3' ends ...... and transcription termination
@en
GC skew at the 5' and 3' ends ...... and transcription termination
@nl
prefLabel
GC skew at the 5' and 3' ends ...... and transcription termination
@ast
GC skew at the 5' and 3' ends ...... and transcription termination
@en
GC skew at the 5' and 3' ends ...... and transcription termination
@nl
P2093
P2860
P356
P1433
P1476
GC skew at the 5' and 3' ends ...... and transcription termination
@en
P2093
Paul A Ginno
Yoong Wearn Lim
P2860
P304
P356
10.1101/GR.158436.113
P577
2013-07-18T00:00:00Z