Identification of the gene cluster for the dithiolopyrrolone antibiotic holomycin in Streptomyces clavuligerus.
about
The fish pathogen Yersinia ruckeri produces holomycin and uses an RNA methyltransferase for self-resistanceFlavoenzymes: versatile catalysts in biosynthetic pathwaysExploiting adaptive laboratory evolution of Streptomyces clavuligerus for antibiotic discovery and overproductionDithiolopyrrolones: biosynthesis, synthesis, and activity of a unique class of disulfide-containing antibiotics.A natural plasmid uniquely encodes two biosynthetic pathways creating a potent anti-MRSA antibioticCharacterization of DNA-binding sequences for CcaR in the cephamycin-clavulanic acid supercluster of Streptomyces clavuligerus.Genome sequences of three tunicamycin-producing Streptomyces Strains, S. chartreusis NRRL 12338, S. chartreusis NRRL 3882, and S. lysosuperificus ATCC 31396.Genome mining reveals unlocked bioactive potential of marine Gram-negative bacteria.Production of bioactive secondary metabolites by marine vibrionaceae.Microbial competition between Bacillus subtilis and Staphylococcus aureus monitored by imaging mass spectrometryAntimicrobial peptides from marine proteobacteria.Dithiolopyrrolone natural products: isolation, synthesis and biosynthesis.Engineered Streptomyces avermitilis host for heterologous expression of biosynthetic gene cluster for secondary metabolitesBioactive compounds synthesized by non-ribosomal peptide synthetases and type-I polyketide synthases discovered through genome-mining and metagenomics.Structure and noncanonical chemistry of nonribosomal peptide biosynthetic machinery.Holomycin, a dithiolopyrrolone compound produced by Streptomyces clavuligerus.Biosynthesis of polyketides by trans-AT polyketide synthases.Simple "on-demand" production of bioactive natural products.Identification of pyrroloformamide as a cytokinesis modulator.Biosynthesis and function of simple amides in Xenorhabdus doucetiae.Molecular genetics of naringenin biosynthesis, a typical plant secondary metabolite produced by Streptomyces clavuligerus.Identification and characterization of Streptomyces flavogriseus NJ-4 as a novel producer of actinomycin D and holomycin.Complete Genome Sequence of Streptomyces clavuligerus F613-1, an Industrial Producer of Clavulanic AcidInvestigating the Biosynthesis of Natural Products from Marine Proteobacteria: A Survey of Molecules and Strategies.A backup plan for self-protection: S-methylation of holomycin biosynthetic intermediates in Streptomyces clavuligerus.Enzymatic basis of "hybridity" in thiomarinol biosynthesisStreptomyces clavuligerus HlmI is an intramolecular disulfide-forming dithiol oxidase in holomycin biosynthesis.Induction of holomycin production and complex metabolic changes by the argR mutation in Streptomyces clavuligerus NP1.Identification of two putative acyltransferase genes potentially implicated in dithiolopyrrolone biosyntheses in Saccharothrix algeriensis NRRL B-24137.Discovering the potential of S. clavuligerus for bioactive compound production: cross-talk between the chromosome and the pSCL4 megaplasmid.Two Flavoenzymes Catalyze the Post-Translational Generation of 5-Chlorotryptophan and 2-Aminovinyl-Cysteine during NAI-107 Biosynthesis.Antibiotics from Gram-negative bacteria: a comprehensive overview and selected biosynthetic highlights.Selected Mutations Reveal New Intermediates in the Biosynthesis of Mupirocin and the Thiomarinol Antibiotics.Selected Mutations Reveal New Intermediates in the Biosynthesis of Mupirocin and the Thiomarinol Antibiotics
P2860
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P2860
Identification of the gene cluster for the dithiolopyrrolone antibiotic holomycin in Streptomyces clavuligerus.
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2010 nî lūn-bûn
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2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Identification of the gene clu ...... in Streptomyces clavuligerus.
@ast
Identification of the gene clu ...... in Streptomyces clavuligerus.
@en
Identification of the gene clu ...... in Streptomyces clavuligerus.
@nl
type
label
Identification of the gene clu ...... in Streptomyces clavuligerus.
@ast
Identification of the gene clu ...... in Streptomyces clavuligerus.
@en
Identification of the gene clu ...... in Streptomyces clavuligerus.
@nl
prefLabel
Identification of the gene clu ...... in Streptomyces clavuligerus.
@ast
Identification of the gene clu ...... in Streptomyces clavuligerus.
@en
Identification of the gene clu ...... in Streptomyces clavuligerus.
@nl
P2860
P356
P1476
Identification of the gene clu ...... in Streptomyces clavuligerus.
@en
P2093
Christopher T Walsh
P2860
P304
19731-19735
P356
10.1073/PNAS.1014140107
P407
P50
P577
2010-11-01T00:00:00Z