Numb antagonizes Notch signaling to specify sibling neuron cell fates.
about
LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradationRegulation of myeloid leukaemia by the cell-fate determinant MusashiNotch activity in neural progenitors coordinates cytokinesis and asymmetric differentiationNon-canonical Notch signaling: emerging role and mechanismNotch signaling and neural connectivityThe Numb/p53 circuitry couples replicative self-renewal and tumor suppression in mammary epithelial cells.Arl2- and Msps-dependent microtubule growth governs asymmetric divisionZebrafish numb and numblike are involved in primitive erythrocyte differentiationGenetic and Environmental Control of Neurodevelopmental Robustness in Drosophila.Keeping neural progenitor cells on a short leash during Drosophila neurogenesisStructure of a Numb PTB domain-peptide complex suggests a basis for diverse binding specificityAsymmetric cell divisionRNA-binding protein Musashi1 modulates glioma cell growth through the post-transcriptional regulation of Notch and PI3 kinase/Akt signaling pathwaysMammalian numb-interacting protein 1/dual oxidase maturation factor 1 directs neuronal fate in stem cellsThe mammalian numb phosphotyrosine-binding domain. Characterization of binding specificity and identification of a novel PDZ domain-containing numb binding protein, LNXNotch inhibitors as a new tool in the war on cancer: a pathway to watch.Dynamic regulation of mammalian numb by G protein-coupled receptors and protein kinase C activation: Structural determinants of numb association with the cortical membraneEpicardial spindle orientation controls cell entry into the myocardiumTowards a molecular understanding of Drosophila hearingNumb family proteins are essential for cardiac morphogenesis and progenitor differentiationNumb is not a critical regulator of Notch-mediated cell fate decisions in the developing chick inner ear.Prenatal neurobiological development: molecular mechanisms and anatomical change.Postmitotic specification of Drosophila insulinergic neurons from pioneer neuronsLineage-specific effects of Notch/Numb signaling in post-embryonic development of the Drosophila brain.Stress-induced switch in Numb isoforms enhances Notch-dependent expression of subtype-specific transient receptor potential channel.Numb proteins specify asymmetric cell fates via an endocytosis- and proteasome-independent pathway.Arbiter of differentiation and death: Notch signaling meets apoptosis.Inscuteable-independent apicobasally oriented asymmetric divisions in the Drosophila embryonic CNS.The H3K27me3 demethylase dUTX is a suppressor of Notch- and Rb-dependent tumors in DrosophilaCharacterization of four mammalian numb protein isoforms. Identification of cytoplasmic and membrane-associated variants of the phosphotyrosine binding domain.Coe genes are expressed in differentiating neurons in the central nervous system of protostomes.Cellular studies of auditory hair cell regeneration in birdsAsymmetric cell division and Notch signaling specify dopaminergic neurons in Drosophila.Coordinating cell fate and morphogenesis in Drosophila renal tubules.Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain.The tumor suppressive role of NUMB isoform 1 in esophageal squamous cell carcinoma.Membrane targeting and asymmetric localization of Drosophila partner of inscuteable are discrete steps controlled by distinct regions of the protein.A novel transmembrane protein recruits numb to the plasma membrane during asymmetric cell division.The role of eNSCs in neurodegenerative disease.Two novel human NUMB isoforms provide a potential link between development and cancer.
P2860
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P2860
Numb antagonizes Notch signaling to specify sibling neuron cell fates.
description
1996 nî lūn-bûn
@nan
1996 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Numb antagonizes Notch signaling to specify sibling neuron cell fates.
@ast
Numb antagonizes Notch signaling to specify sibling neuron cell fates.
@en
Numb antagonizes Notch signaling to specify sibling neuron cell fates.
@nl
type
label
Numb antagonizes Notch signaling to specify sibling neuron cell fates.
@ast
Numb antagonizes Notch signaling to specify sibling neuron cell fates.
@en
Numb antagonizes Notch signaling to specify sibling neuron cell fates.
@nl
prefLabel
Numb antagonizes Notch signaling to specify sibling neuron cell fates.
@ast
Numb antagonizes Notch signaling to specify sibling neuron cell fates.
@en
Numb antagonizes Notch signaling to specify sibling neuron cell fates.
@nl
P1433
P1476
Numb antagonizes Notch signaling to specify sibling neuron cell fates.
@en
P356
10.1016/S0896-6273(00)80277-9
P407
P577
1996-07-01T00:00:00Z