The paradox of mitochondrial dysfunction and extended longevity.
about
The mitochondrial unfolded protein response—synchronizing genomesComplex-I-ty in agingFAH domain containing protein 1 (FAHD-1) is required for mitochondrial function and locomotion activity in C. elegansDLK-1, SEK-3 and PMK-3 Are Required for the Life Extension Induced by Mitochondrial Bioenergetic Disruption in C. elegansA Select Subset of Electron Transport Chain Genes Associated with Optic Atrophy Link Mitochondria to Axon Regeneration in Caenorhabditis elegans2-Oxoglutarate-dependent dioxygenases are sensors of energy metabolism, oxygen availability, and iron homeostasis: potential role in the regulation of aging process.Collaboration between mitochondria and the nucleus is key to long life in Caenorhabditis elegans.Maximal oxidative capacity during exercise is associated with skeletal muscle fuel selection and dynamic changes in mitochondrial protein acetylationMitochondrial maintenance failure in aging and role of sexual dimorphism.UPR(mt)-mediated cytoprotection and organismal aging.In vitro organo-protective effect of bark extracts from Syzygium guineense var macrocarpum against ferric-nitrilotriacetate-induced stress in wistar rats homogenates.Mitochondrial metabolites extend lifespan.Glutathione S-transferase mediates an ageing response to mitochondrial dysfunctionThe Role of Reactive Oxygen Species in the Pathogenesis of Alzheimer's Disease, Parkinson's Disease, and Huntington's Disease: A Mini Review.Mitochondrial responsibility in ageing process: innocent, suspect or guilty.Mitochondrial Retrograde Signaling: Triggers, Pathways, and Outcomes.Sex-Specific Gene Expression and Life Span Regulation.Molecular and biological hallmarks of ageing.The Emergence of Geroscience as an Interdisciplinary Approach to the Enhancement of Health Span and Life Span.AMPK and HIF signaling pathways regulate both longevity and cancer growth: the good news and the bad news about survival mechanisms.Post-Translational Oxidative Modifications of Mitochondrial Complex I (NADH: Ubiquinone Oxidoreductase): Implications for Pathogenesis and Therapeutics in Human Diseases.Pharynx mitochondrial [Ca2+] dynamics in live C. elegans worms during aging.Mitochondrial Manipulation and the Quest for Alzheimer's Treatments.Beyond the polymerase-γ theory: Production of ROS as a mode of NRTI-induced mitochondrial toxicity.Cell Biology of the Mitochondrion.The mitochondrial UPR: mechanisms, physiological functions and implications in ageing.Activation of DAF-16/FOXO by reactive oxygen species contributes to longevity in long-lived mitochondrial mutants in Caenorhabditis elegans.Lifelong reduction in complex IV induces tissue-specific metabolic effects but does not reduce lifespan or healthspan in mice.Genetic inhibition of an ATP synthase subunit extends lifespan in C. elegans
P2860
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P2860
The paradox of mitochondrial dysfunction and extended longevity.
description
2014 nî lūn-bûn
@nan
2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
The paradox of mitochondrial dysfunction and extended longevity.
@ast
The paradox of mitochondrial dysfunction and extended longevity.
@en
The paradox of mitochondrial dysfunction and extended longevity.
@nl
type
label
The paradox of mitochondrial dysfunction and extended longevity.
@ast
The paradox of mitochondrial dysfunction and extended longevity.
@en
The paradox of mitochondrial dysfunction and extended longevity.
@nl
prefLabel
The paradox of mitochondrial dysfunction and extended longevity.
@ast
The paradox of mitochondrial dysfunction and extended longevity.
@en
The paradox of mitochondrial dysfunction and extended longevity.
@nl
P2860
P1476
The paradox of mitochondrial dysfunction and extended longevity.
@en
P2093
Shane L Rea
P2860
P304
P356
10.1016/J.EXGER.2014.03.016
P577
2014-04-01T00:00:00Z