Glutathione synthesis is diminished in patients with uncontrolled diabetes and restored by dietary supplementation with cysteine and glycine
about
Metabolomics and Type 2 Diabetes: Translating Basic Research into Clinical ApplicationDiabetes and Alzheimer disease, two overlapping pathologies with the same background: oxidative stressThioredoxins, glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: from cofactors to antioxidants to redox signalingFinding needles in a haystack: application of network analysis and target enrichment studies for the identification of potential anti-diabetic phytochemicalsRandom Survival Forest in practice: a method for modelling complex metabolomics data in time to event analysis.Hydrogen sulfide upregulates glutamate-cysteine ligase catalytic subunit, glutamate-cysteine ligase modifier subunit, and glutathione and inhibits interleukin-1β secretion in monocytes exposed to high glucose levels.Vitamin D upregulates glutamate cysteine ligase and glutathione reductase, and GSH formation, and decreases ROS and MCP-1 and IL-8 secretion in high-glucose exposed U937 monocytesEffect of chromium dinicocysteinate supplementation on circulating levels of insulin, TNF-α, oxidative stress, and insulin resistance in type 2 diabetic subjects: randomized, double-blind, placebo-controlled studyGene-Diet Interactions in Type 2 Diabetes: The Chicken and Egg DebatePersonalized metabolomics for predicting glucose tolerance changes in sedentary women after high-intensity interval training.Vitamin D and L-cysteine levels correlate positively with GSH and negatively with insulin resistance levels in the blood of type 2 diabetic patientsHydrogen sulfide prevents hydrogen peroxide-induced activation of epithelial sodium channel through a PTEN/PI(3,4,5)P3 dependent pathwaySerum glycine is associated with regional body fat and insulin resistance in functionally-limited older adultsDeficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementationElevated serum levels of cysteine and tyrosine: early biomarkers in asymptomatic adults at increased risk of developing metabolic syndrome.Deciphering deterioration mechanisms of complex diseases based on the construction of dynamic networks and systems analysis.Hydrogen sulfide and L-cysteine increase phosphatidylinositol 3,4,5-trisphosphate (PIP3) and glucose utilization by inhibiting phosphatase and tensin homolog (PTEN) protein and activating phosphoinositide 3-kinase (PI3K)/serine/threonine protein kinPlasma biomarkers of oxidative stress and genetic variants in age-related macular degeneration.Can L-Cysteine and Vitamin D Rescue Vitamin D and Vitamin D Binding Protein Levels in Blood Plasma of African American Type 2 Diabetic Patients?Nutritional regulation of insulin secretion: implications for diabetes.NADPH oxidase 4 regulates homocysteine metabolism and protects against acetaminophen-induced liver damage in miceIncrease in Blood Glutathione and Erythrocyte Proteins Related to Glutathione Generation, Reduction and Utilization in African-American Old Women with Diabetes.Identification and Antioxidant Activity of the Extracts of Eugenia uniflora Leaves. Characterization of the Anti-Inflammatory Properties of Aqueous Extract on Diabetes Expression in an Experimental Model of Spontaneous Type 1 Diabetes (NOD Mice).Glutaredoxin mediated redox effects of coenzyme Q10 treatment in type 1 and type 2 diabetes patientsIdentification of serum metabolites associated with risk of type 2 diabetes using a targeted metabolomic approach.1,25(OH)2D3 inhibits oxidative stress and monocyte adhesion by mediating the upregulation of GCLC and GSH in endothelial cells treated with acetoacetate (ketosis).Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetesGlutathione maintenance mitigates age-related susceptibility to redox cycling agents.Hepatic transcriptome implications for palm fruit juice deterrence of type 2 diabetes mellitus in young male Nile rats.Effect of increasing glutathione with cysteine and glycine supplementation on mitochondrial fuel oxidation, insulin sensitivity, and body composition in older HIV-infected patients.Associations of FPG, A1C and disease duration with protein markers of oxidative damage and antioxidative defense in type 2 diabetes and diabetic retinopathy.Metabolic heterogeneity of follicular amino acids in polycystic ovary syndrome is affected by obesity and related to pregnancy outcome.A Western diet induced NAFLD in LDLR(-/)(-) mice is associated with reduced hepatic glutathione synthesis.Mitochondrial glutathione depletion reveals a novel role for the pyruvate dehydrogenase complex as a key H2O2-emitting source under conditions of nutrient overload.Plasma-free amino acid profiles are predictors of cancer and diabetes development.High-precision mass spectrometric analysis using stable isotopes in studies of children.L-cysteine supplementation as an adjuvant therapy for type-2 diabetes.Glycine metabolism in animals and humans: implications for nutrition and health.A new perspective on the importance of glycine conjugation in the metabolism of aromatic acids.Immunological mechanisms contributing to the double burden of diabetes and intracellular bacterial infections.
P2860
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P2860
Glutathione synthesis is diminished in patients with uncontrolled diabetes and restored by dietary supplementation with cysteine and glycine
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Glutathione synthesis is dimin ...... tion with cysteine and glycine
@ast
Glutathione synthesis is dimin ...... tion with cysteine and glycine
@en
Glutathione synthesis is dimin ...... tion with cysteine and glycine
@nl
type
label
Glutathione synthesis is dimin ...... tion with cysteine and glycine
@ast
Glutathione synthesis is dimin ...... tion with cysteine and glycine
@en
Glutathione synthesis is dimin ...... tion with cysteine and glycine
@nl
prefLabel
Glutathione synthesis is dimin ...... tion with cysteine and glycine
@ast
Glutathione synthesis is dimin ...... tion with cysteine and glycine
@en
Glutathione synthesis is dimin ...... tion with cysteine and glycine
@nl
P2093
P2860
P356
P1433
P1476
Glutathione synthesis is dimin ...... tion with cysteine and glycine
@en
P2093
Anuradha P Guthikonda
Ashok Balasubramanyam
Farook Jahoor
Rajagopal V Sekhar
Sanjeet G Patel
Siripoom V McKay
Vasumathi T Reddy
P2860
P304
P356
10.2337/DC10-1006
P407
P577
2010-10-07T00:00:00Z