The evolving role of chemical synthesis in antibacterial drug discovery. - Test2 - elhamkhani - TriplyDB

The evolving role of chemical synthesis in antibacterial drug discovery.

The evolving role of chemical synthesis in antibacterial drug discovery.

http://www.wikidata.org/entity/Q34427652

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From Discovery to Production: Biotechnology of Marine Fungi for the Production of New Antibiotics Lanthipeptides: chemical synthesis versus in vivo biosynthesis as tools for pharmaceutical production Cytochrome P450 OxyBtei catalyzes the first phenolic coupling step in teicoplanin biosynthesis Structure of the terminal PCP domain of the non-ribosomal peptide synthetase in teicoplanin biosynthesis Targeting Antibiotic Resistance Elucidation of the Mode of Action of a New Antibacterial Compound Active against Staphylococcus aureus and Pseudomonas aeruginosa Endless Resistance. Endless Antibiotics?Total synthesis of viridicatumtoxin B and analogues thereof: strategy evolution, structural revision, and biological evaluation.Axinellamines as broad-spectrum antibacterial agents: scalable synthesis and biology.Binaphthyl-1,2,3-triazole peptidomimetics with activity against Clostridium difficile and other pathogenic bacteria.A platform for the discovery of new macrolide antibiotics.New Structural Templates for Clinically Validated and Novel Targets in Antimicrobial Drug Research and Development.The effect of iron plaque on uptake and translocation of norfloxacin in rice seedlings grown in paddy soil.Harnessing natural product assembly lines: structure, promiscuity, and engineering.Drugging Membrane Protein Interactions.Eravacycline for the treatment of intra-abdominal infections.Design and synthesis of analogues of natural products.Chemical and Biological Aspects of Nutritional Immunity - Perspectives for New Anti-infectives Targeting Iron Uptake Systems.Toolbox for Antibiotics Discovery from Microorganisms.Ribosome-Templated Azide-Alkyne Cycloadditions: Synthesis of Potent Macrolide Antibiotics by In Situ Click Chemistry.Synthesis of Antibiotics.Short history of regulations and approved indications of antimicrobial drugs for food animals in the USA.Rapid access to glycopeptide antibiotic precursor peptides coupled with cytochrome P450-mediated catalysis: towards a biomimetic synthesis of glycopeptide antibiotics.Enantioselective Organocatalytic Diels-Alder Trapping of Photochemically Generated Hydroxy-o-Quinodimethanes.Next-generation approaches to understand and combat the antibiotic resistome.Total Syntheses of Vancomycin-Related Glycopeptide Antibiotics and Key Analogues.Total Synthesis and Functional Evaluation of Fourteen Derivatives of Lysocin E: Importance of Cationic, Hydrophobic, and Aromatic Moieties for Antibacterial Activity.Biomimetic Assembly Lines Producing Natural Product Analogs: Strategies from a Versatile Manifold to Skeletally Diverse Scaffolds.The advancement of multidimensional QSAR for novel drug discovery - where are we headed?Natural product analogues: towards a blueprint for analogue-focused synthesis.Bifunctional antimicrobial conjugates and hybrid antimicrobials.Rapid killing of bacteria by a new type of photosensitizer.Total Synthesis and Structural Reassignment of Aspergillomarasmine A.Synthesis and antimicrobial activity of binaphthyl-based, functionalized oxazole and thiazole peptidomimetics.Ti(Oi-Pr)4-promoted photoenolization Diels-Alder reaction to construct polycyclic rings and its synthetic applications.The Difference a Single Atom Can Make: Synthesis and Design at the Chemistry-Biology Interface.Drug discovery: Fighting evolution with chemical synthesis.Structure-Based Design and Synthesis of Apramycin-Paromomycin Analogues: Importance of the Configuration at the 6'-Position and Differences between the 6'-Amino and Hydroxy Series.Late-stage chemoselective functional-group manipulation of bioactive natural products with super-electrophilic silylium ions.Are highly morphed peptide frameworks lurking silently in microbial genomes valuable as next generation antibiotic scaffolds?

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P2860

The evolving role of chemical synthesis in antibacterial drug discovery.

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2014 nî lūn-bûn

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2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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The evolving role of chemical synthesis in antibacterial drug discovery.

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The evolving role of chemical synthesis in antibacterial drug discovery.

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The evolving role of chemical synthesis in antibacterial drug discovery.

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The evolving role of chemical synthesis in antibacterial drug discovery.

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The evolving role of chemical synthesis in antibacterial drug discovery.

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The evolving role of chemical synthesis in antibacterial drug discovery.

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The evolving role of chemical synthesis in antibacterial drug discovery.

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The evolving role of chemical synthesis in antibacterial drug discovery.

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The evolving role of chemical synthesis in antibacterial drug discovery.

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The evolving role of chemical synthesis in antibacterial drug discovery.

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Ian B Seiple

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8840-8869

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10.1002/ANIE.201310843

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