STIM1 triggers a gating rearrangement at the extracellular mouth of the ORAI1 channel.
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Pathophysiological Significance of Store-Operated Calcium Entry in Megakaryocyte Function: Opening New Paths for Understanding the Role of Calcium in ThrombopoiesisTMEM110 regulates the maintenance and remodeling of mammalian ER-plasma membrane junctions competent for STIM-ORAI signalingStore-operated calcium entry: Mechanisms and modulation.Alternative splicing converts STIM2 from an activator to an inhibitor of store-operated calcium channelsCritical role for Orai1 C-terminal domain and TM4 in CRAC channel gating.The STIM1-ORAI1 microdomainCooperative Binding of Stromal Interaction Molecule 1 (STIM1) to the N and C Termini of Calcium Release-activated Calcium Modulator 1 (Orai1).Orai1 pore residues control CRAC channel inactivation independently of calmodulin.The inactivation domain of STIM1 is functionally coupled with the Orai1 pore to enable Ca2+-dependent inactivation.Sigma1 receptors inhibit store-operated Ca2+ entry by attenuating coupling of STIM1 to Orai1Disulfide Cross-linking of a Multidrug and Toxic Compound Extrusion Transporter Impacts Multidrug Efflux.Oocyte activation deficiency: a role for an oocyte contribution?Electrophysiological Features of Single Store-Operated Calcium Channels in HEK S4 Cell Line with Stable STIM1 Protein Knockdown.Molecular mechanisms of STIM/Orai communication.CRAC channel gating and its modulation by STIM1 and 2-aminoethoxydiphenyl borate.Molecular mechanisms underlying inhibition of STIM1-Orai1-mediated Ca2+ entry induced by 2-aminoethoxydiphenyl borate.Ca(2+) Channel Re-localization to Plasma-Membrane Microdomains Strengthens Activation of Ca(2+)-Dependent Nuclear Gene Expression.The STIM-Orai coupling interface and gating of the Orai1 channel.Pore opening mechanism of CRAC channels.Oocyte Activation and Fertilisation: Crucial Contributors from the Sperm and Oocyte.The STIM1-binding site nexus remotely controls Orai1 channel gating.STIM1 activates CRAC channels through rotation of the pore helix to open a hydrophobic gate.The Orai1 Store-operated Calcium Channel Functions as a Hexamer.Authentic CRAC channel activity requires STIM1 and the conserved portion of the Orai N-terminus.Ca2+ and lipid signals hold hands at endoplasmic reticulum-plasma membrane contact sites.The STIM-Orai Pathway: Conformational Coupling Between STIM and Orai in the Activation of Store-Operated Ca2+ Entry.The STIM-Orai Pathway: The Interactions Between STIM and Orai.The STIM-Orai Pathway: Orai, the Pore-Forming Subunit of the CRAC Channel.Store-Operated Calcium Channels.
P2860
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P2860
STIM1 triggers a gating rearrangement at the extracellular mouth of the ORAI1 channel.
description
2014 nî lūn-bûn
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2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հոտեմբերին հրատարակված գիտական հոդված
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年學術文章
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name
STIM1 triggers a gating rearrangement at the extracellular mouth of the ORAI1 channel.
@ast
STIM1 triggers a gating rearrangement at the extracellular mouth of the ORAI1 channel.
@en
STIM1 triggers a gating rearrangement at the extracellular mouth of the ORAI1 channel.
@nl
type
label
STIM1 triggers a gating rearrangement at the extracellular mouth of the ORAI1 channel.
@ast
STIM1 triggers a gating rearrangement at the extracellular mouth of the ORAI1 channel.
@en
STIM1 triggers a gating rearrangement at the extracellular mouth of the ORAI1 channel.
@nl
prefLabel
STIM1 triggers a gating rearrangement at the extracellular mouth of the ORAI1 channel.
@ast
STIM1 triggers a gating rearrangement at the extracellular mouth of the ORAI1 channel.
@en
STIM1 triggers a gating rearrangement at the extracellular mouth of the ORAI1 channel.
@nl
P2093
P2860
P356
P1476
STIM1 triggers a gating rearrangement at the extracellular mouth of the ORAI1 channel.
@en
P2093
Ariel Quintana
Nupura Hirve
Patrick G Hogan
Sahasransu Mahapatra
P2860
P2888
P356
10.1038/NCOMMS6164
P577
2014-10-09T00:00:00Z
P5875
P6179
1003509388