Targeted inactivation of kinesin-1 in pancreatic β-cells in vivo leads to insulin secretory deficiency.
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Microtubules Negatively Regulate Insulin Secretion in Pancreatic β Cells.Defective mitophagy driven by dysregulation of rheb and KIF5B contributes to mitochondrial reactive oxygen species (ROS)-induced nod-like receptor 3 (NLRP3) dependent proinflammatory response and aggravates lipotoxicityStable kinesin and dynein assemblies drive the axonal transport of mammalian prion protein vesicles.Insight into insulin secretion from transcriptome and genetic analysis of insulin-producing cells of DrosophilaPhospholipase C-related catalytically inactive protein (PRIP) controls KIF5B-mediated insulin secretionRNAi screening in primary human hepatocytes of genes implicated in genome-wide association studies for roles in type 2 diabetes identifies roles for CAMK1D and CDKAL1, among others, in hepatic glucose regulation.Analysis of Kif5b expression during mouse kidney development.Dynamin 2 regulates biphasic insulin secretion and plasma glucose homeostasisAdvanced Glycation End Products Impair Glucose-Stimulated Insulin Secretion of a Pancreatic β-Cell Line INS-1-3 by Disturbance of Microtubule Cytoskeleton via p38/MAPK ActivationKinesin-1 controls mast cell degranulation and anaphylaxis through PI3K-dependent recruitment to the granular Slp3/Rab27b complex.Tacrolimus in pancreas transplant: a focus on toxicity, diabetogenic effect and drug-drug interactions.Multimodal nonlinear optical microscopy reveals critical role of kinesin-1 in cartilage development.Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.Terminal transport of lytic granules to the immune synapse is mediated by the kinesin-1/Slp3/Rab27a complex.PICK1 is Essential for Insulin Production and the Maintenance of Glucose Homeostasis.Metabolic amplification of insulin secretion by glucose is independent of β-cell microtubules.
P2860
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P2860
Targeted inactivation of kinesin-1 in pancreatic β-cells in vivo leads to insulin secretory deficiency.
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Targeted inactivation of kines ...... insulin secretory deficiency.
@ast
Targeted inactivation of kines ...... insulin secretory deficiency.
@en
Targeted inactivation of kines ...... insulin secretory deficiency.
@nl
type
label
Targeted inactivation of kines ...... insulin secretory deficiency.
@ast
Targeted inactivation of kines ...... insulin secretory deficiency.
@en
Targeted inactivation of kines ...... insulin secretory deficiency.
@nl
prefLabel
Targeted inactivation of kines ...... insulin secretory deficiency.
@ast
Targeted inactivation of kines ...... insulin secretory deficiency.
@en
Targeted inactivation of kines ...... insulin secretory deficiency.
@nl
P2093
P2860
P50
P356
P1433
P1476
Targeted inactivation of kines ...... insulin secretory deficiency.
@en
P2093
Jian-Dong Huang
Kwok-Ming Yao
Qianni Cheng
Xin-Mei Zhang
P2860
P304
P356
10.2337/DB09-1078
P407
P577
2010-09-24T00:00:00Z