Identification of PADI2 as a potential breast cancer biomarker and therapeutic target. - Test2 - elhamkhani - TriplyDB

Identification of PADI2 as a potential breast cancer biomarker and therapeutic target.

Identification of PADI2 as a potential breast cancer biomarker and therapeutic target.

http://www.wikidata.org/entity/Q34461456

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Protein Arginine Deiminases and Associated Citrullination: Physiological Functions and Diseases Associated with Dysregulation Peptidylarginine Deiminase 3 (PAD3) Is Upregulated by Prolactin Stimulation of CID-9 Cells and Expressed in the Lactating Mouse Mammary Gland Whole exome sequencing identifies genetic variants in inherited thrombocytopenia with secondary qualitative function defects Role of peptidylarginine deiminase 2 (PAD2) in mammary carcinoma cell migration A FluoPol-ABPP PAD2 high-throughput screen identifies the first calcium site inhibitor targeting the PADs.Expression of Cancer/Testis genes in ductal carcinoma in situ and benign lesions of the breast.Chemical biology of protein arginine modifications in epigenetic regulation The receptor for advanced glycation end products (RAGE) enhances autophagy and neutrophil extracellular traps in pancreatic cancer.Utilization of the Soft Agar Colony Formation Assay to Identify Inhibitors of Tumorigenicity in Breast Cancer Cells.Decreased severity of experimental autoimmune arthritis in peptidylarginine deiminase type 4 knockout mice.Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design.Activation of PAD4 in NET formation.Chemical Proteomic Platform To Identify Citrullinated Proteins Detection and identification of protein citrullination in complex biological systems Protein Arginine Methylation and Citrullination in Epigenetic Regulation PADI2 gene confers susceptibility to breast cancer and plays tumorigenic role via ACSL4, BINC3 and CA9 signaling CELF1 is a central node in post-transcriptional regulatory programmes underlying EMT Risk analysis of colorectal cancer incidence by gene expression analysis.Investigating the expression, effect and tumorigenic pathway of PADI2 in tumors.Chemical and biological methods to detect post-translational modifications of arginine.Insights into the mechanism of streptonigrin-induced protein arginine deiminase inactivation A novel role for peptidylarginine deiminases in microvesicle release reveals therapeutic potential of PAD inhibition in sensitizing prostate cancer cells to chemotherapy.Mechanistic studies of protein arginine deiminase 2: evidence for a substrate-assisted mechanism A novel role for protein arginine deiminase 4 in pluripotency: the emerging role of citrullinated histone H1 in cellular programming.PAD1 promotes epithelial-mesenchymal transition and metastasis in triple-negative breast cancer cells by regulating MEK1-ERK1/2-MMP2 signaling.A cellular model reflecting the phenotypic heterogeneity of mutant HRAS driven squamous cell carcinoma.Citrullination/Methylation Crosstalk on Histone H3 Regulates ER-Target Gene Transcription.Design, synthesis, and biological evaluation of tetrazole analogs of Cl-amidine as protein arginine deiminase inhibitors.PAD2 Activity Monitored via a Fluorescent Substrate Analog.Peptidylarginine Deiminases-Roles in Cancer and Neurodegeneration and Possible Avenues for Therapeutic Intervention via Modulation of Exosome and Microvesicle (EMV) Release?Eugenol alleviated breast precancerous lesions through HER2/PI3K-AKT pathway-induced cell apoptosis and S-phase arrest.The lncRNA HOXA11-AS functions as a competing endogenous RNA to regulate PADI2 expression by sponging miR-125a-5p in liver metastasis of colorectal cancer.Human Deiminases: Isoforms, Substrate Specificities, Kinetics, and Detection.Development of a Selective Inhibitor of Protein Arginine Deiminase 2.The Development of Benzimidazole-Based Clickable Probes for the Efficient Labeling of Cellular Protein Arginine Deiminases (PADs).BB-Cl-Amidine as a novel therapeutic for canine and feline mammary cancer via activation of the endoplasmic reticulum stress pathway.Peptidyl arginine deiminase 2 (Padi2) is expressed in Sertoli cells in a specific manner and regulated by SOX9 during testicular development

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P2860

Identification of PADI2 as a potential breast cancer biomarker and therapeutic target.

http://www.wikidata.org/entity/Q34461456

description

2012 nî lūn-bûn

@nan

2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2012 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Identification of PADI2 as a potential breast cancer biomarker and therapeutic target.

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Identification of PADI2 as a potential breast cancer biomarker and therapeutic target.

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Identification of PADI2 as a potential breast cancer biomarker and therapeutic target.

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Identification of PADI2 as a potential breast cancer biomarker and therapeutic target.

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Identification of PADI2 as a potential breast cancer biomarker and therapeutic target.

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Identification of PADI2 as a potential breast cancer biomarker and therapeutic target.

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Identification of PADI2 as a potential breast cancer biomarker and therapeutic target.

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Identification of PADI2 as a potential breast cancer biomarker and therapeutic target.

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Identification of PADI2 as a potential breast cancer biomarker and therapeutic target.

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Identification of PADI2 as a potential breast cancer biomarker and therapeutic target.

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Identification of PADI2 as a potential breast cancer biomarker and therapeutic target.

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Identification of PADI2 as a potential breast cancer biomarker and therapeutic target.

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Identification of PADI2 as a potential breast cancer biomarker and therapeutic target.

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Ashley M Palmer

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Heike C Breuer

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Joe W Gray

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Lynne J Anguish

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Sunish Mohanan

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An intraductal human-in-mouse transplantation model mimics the subtypes of ductal carcinoma in situ

Molecular characterization of peptidylarginine deiminase in HL-60 cells induced by retinoic acid and 1alpha,25-dihydroxyvitamin D(3)

Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor α target gene activation

AU-rich elements and associated factors: are there unifying principles?

HuR regulates p21 mRNA stabilization by UV light

AREsite: a database for the comprehensive investigation of AU-rich elements

A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

Changes in gene expression during the development of mammary tumors in MMTV-Wnt-1 transgenic mice.

A rigorous method for multigenic families' functional annotation: the peptidyl arginine deiminase (PADs) proteins family example.

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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