cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection. - Test2 - elhamkhani - TriplyDB

cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection.

cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection.

http://www.wikidata.org/entity/Q34469746

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Stress Beyond Translation: Poxviruses and More Dynamic Response of IFI16 and Promyelocytic Leukemia Nuclear Body Components to Herpes Simplex Virus 1 Infection The Role of Nuclear Antiviral Factors against Invading DNA Viruses: The Immediate Fate of Incoming Viral Genomes Evasion of host antiviral innate immunity by HSV-1, an update DNA sensor cGAS-mediated immune recognition BRCA1 Regulates IFI16 Mediated Nuclear Innate Sensing of Herpes Viral DNA and Subsequent Induction of the Innate Inflammasome and Interferon-β Responses Viral evasion of intracellular DNA and RNA sensing Unique Loss of the PYHIN Gene Family in Bats Amongst Mammals: Implications for Inflammasome Sensing Herpes Simplex Virus and Interferon Signaling Induce Novel Autophagic Clusters in Sensory Neurons Dengue virus activates cGAS through the release of mitochondrial DNA The U6 snRNA m6A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention.Friend or Foe: Innate Sensing of HIV in the Female Reproductive Tract.Exosomes maintain cellular homeostasis by excreting harmful DNA from cells.IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP DNA-sensing inflammasomes: regulation of bacterial host defense and the gut microbiota.cGAS Senses Human Cytomegalovirus and Induces Type I Interferon Responses in Human Monocyte-Derived Cells.Histone H2B-IFI16 Recognition of Nuclear Herpesviral Genome Induces Cytoplasmic Interferon-β Responses.The emerging role of nuclear viral DNA sensors.Up-regulation of Interferon-inducible protein 16 contributes to psoriasis by modulating chemokine production in keratinocytes.TREX1 Knockdown Induces an Interferon Response to HIV that Delays Viral Infection in Humanized Mice.Role of nucleotide-binding oligomerization domain 1 (NOD1) and its variants in human cytomegalovirus control in vitro and in vivo.Post-translational regulation of inflammasomes.IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes.The Emerging Roles of STING in Bacterial Infections.The cGAS-STING Defense Pathway and Its Counteraction by Viruses.AIM2-Like Receptors Positively and Negatively Regulate the Interferon Response Induced by Cytosolic DNA STING Requires the Adaptor TRIF to Trigger Innate Immune Responses to Microbial Infection Relative Contributions of Herpes Simplex Virus 1 ICP0 and vhs to Loss of Cellular IFI16 Vary in Different Human Cell Types.Innate immune evasion strategies of DNA and RNA viruses.Protect this house: cytosolic sensing of viruses.The Type I Interferon Response and Age-Dependent Susceptibility to Herpes Simplex Virus Infection.Innate Immune Mechanisms and Herpes Simplex Virus Infection and Disease.Regulating STING in health and disease Posttranslational Modification as a Critical Determinant of Cytoplasmic Innate Immune Recognition.Regulatory Interaction between the Cellular Restriction Factor IFI16 and Viral pp65 (pUL83) Modulates Viral Gene Expression and IFI16 Protein Stability.cGAMP Quantification in Virus-Infected Human Monocyte-Derived Cells by HPLC-Coupled Tandem Mass Spectrometry.Herpes Simplex Virus 1 Abrogates the cGAS/STING-Mediated Cytosolic DNA-Sensing Pathway via Its Virion Host Shutoff Protein, UL41.The AIM2-like Receptors Are Dispensable for the Interferon Response to Intracellular DNA.Blowing Off Steam: Virus Inhibition of cGAS DNA Sensing.Full-Length Isoforms of Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen Accumulate in the Cytoplasm of Cells Undergoing the Lytic Cycle of Replication.

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P2860

cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection.

http://www.wikidata.org/entity/Q34469746

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2015 nî lūn-bûn

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2015年の論文

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PNAS.1424637112

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Proceedings of the National Academy of Sciences of the United States of America

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cGAS-mediated stabilization of ...... erpes simplex virus infection.

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Benjamin A Diner

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David M Knipe

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Dustin C Hancks

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Ileana M Cristea

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Megan H Orzalli

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Nels C Elde

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Nicole M Broekema

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P2860

The functional interactome landscape of the human histone deacetylase family

IFI16 is an innate immune sensor for intracellular DNA

IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

Role of IFI 16, a member of the interferon-inducible p200-protein family, in prostate epithelial cellular senescence

Human cytomegalovirus tegument protein pUL83 inhibits IFI16-mediated DNA sensing for immune evasion

Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation

The herpes simplex virus ICP0 RING finger domain inhibits IRF3- and IRF7-mediated activation of interferon-stimulated genes

The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells

c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response

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