Small molecule-triggered Cas9 protein with improved genome-editing specificity.
about
Recent Advances in Genome Editing Using CRISPR/Cas9Gene targeting, genome editing: from Dolly to editorsMinimizing off-Target Mutagenesis Risks Caused by Programmable NucleasesEnabling functional genomics with genome engineeringGenome editing: the road of CRISPR/Cas9 from bench to clinicLigand-binding domains of nuclear receptors facilitate tight control of split CRISPR activityCRISPR/Cas9: Transcending the Reality of Genome Editing.A Convenient Cas9-based Conditional Knockout Strategy for Simultaneously Targeting Multiple Genes in Mouse.Genetic and epigenetic control of gene expression by CRISPR-Cas systems.Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery.Aptazyme-embedded guide RNAs enable ligand-responsive genome editing and transcriptional activation.Rationally engineered Cas9 nucleases with improved specificity.Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage.Multidimensional chemical control of CRISPR-Cas9.Genetic engineering: Chemical control for CRISPR editing.Zebrafish Genome Engineering Using the CRISPR-Cas9 System.Conditional Control of CRISPR/Cas9 Function.Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switchDiverse evolutionary roots and mechanistic variations of the CRISPR-Cas systems.A chemical-inducible CRISPR-Cas9 system for rapid control of genome editing.Adenovirus-Mediated Somatic Genome Editing of Pten by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses.Using Group II Introns for Attenuating the In Vitro and In Vivo Expression of a Homing EndonucleaseConditionally Stabilized dCas9 Activator for Controlling Gene Expression in Human Cell Reprogramming and DifferentiationDNA-binding-domain fusions enhance the targeting range and precision of Cas9.Human germ line editing-roles and responsibilitiesHigh-Content Analysis of CRISPR-Cas9 Gene-Edited Human Embryonic Stem Cells.Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles.Kinetics of the CRISPR-Cas9 effector complex assembly and the role of 3'-terminal segment of guide RNA.Effect of manipulating recombination rates on response to selection in livestock breeding programs.CRISPRs for Optimal Targeting: Delivery of CRISPR Components as DNA, RNA, and Protein into Cultured Cells and Single-Cell Embryos.The Development of a Viral Mediated CRISPR/Cas9 System with Doxycycline Dependent gRNA Expression for Inducible In vitro and In vivo Genome Editing.Integration and exchange of split dCas9 domains for transcriptional controls in mammalian cells.An easy and efficient inducible CRISPR/Cas9 platform with improved specificity for multiple gene targetingSmall-molecule control of protein function through Staudinger reduction.Programmable Genome Editing Tools and their Regulation for Efficient Genome Engineering.Rapid and tunable method to temporally control gene editing based on conditional Cas9 stabilizationInhibition of nonhomologous end joining to increase the specificity of CRISPR/Cas9 genome editing.Modeling Disease In Vivo With CRISPR/Cas9.Synthetic biology: applying biological circuits beyond novel therapies.Creating and evaluating accurate CRISPR-Cas9 scalpels for genomic surgery.
P2860
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P2860
Small molecule-triggered Cas9 protein with improved genome-editing specificity.
description
2015 nî lūn-bûn
@nan
2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Small molecule-triggered Cas9 protein with improved genome-editing specificity.
@ast
Small molecule-triggered Cas9 protein with improved genome-editing specificity.
@en
Small molecule-triggered Cas9 protein with improved genome-editing specificity.
@nl
type
label
Small molecule-triggered Cas9 protein with improved genome-editing specificity.
@ast
Small molecule-triggered Cas9 protein with improved genome-editing specificity.
@en
Small molecule-triggered Cas9 protein with improved genome-editing specificity.
@nl
prefLabel
Small molecule-triggered Cas9 protein with improved genome-editing specificity.
@ast
Small molecule-triggered Cas9 protein with improved genome-editing specificity.
@en
Small molecule-triggered Cas9 protein with improved genome-editing specificity.
@nl
P2093
P2860
P356
P1476
Small molecule-triggered Cas9 protein with improved genome-editing specificity.
@en
P2093
David B Thompson
David R Liu
John A Zuris
Kevin M Davis
Vikram Pattanayak
P2860
P2888
P304
P356
10.1038/NCHEMBIO.1793
P577
2015-04-06T00:00:00Z
P5875
P6179
1042535273