Foreign DNA capture during CRISPR-Cas adaptive immunity.
about
Evolutionary Ecology of Prokaryotic Immune MechanismsA bend, flip and trap mechanism for transposon integrationStructural basis of Cas3 inhibition by the bacteriophage protein AcrF3Structural features of Cas2 from Thermococcus onnurineus in CRISPR-cas system type IV.CRISPR–Cas encoding of a digital movie into the genomes of a population of living bacteriaSpacer-length DNA intermediates are associated with Cas1 in cells undergoing primed CRISPR adaptation.DNA binding specificities of Escherichia coli Cas1-Cas2 integrase drive its recruitment at the CRISPR locusComparative Genomics and Transcriptional Analysis of Flavobacterium columnare Strain ATCC 49512.The spacer size of I-B CRISPR is modulated by the terminal sequence of the protospacer.Structural and dynamic insights into the role of conformational switching in the nuclease activity of the Xanthomonas albilineans Cas2 in CRISPR-mediated adaptive immunity.Cas1 and the Csy complex are opposing regulators of Cas2/3 nuclease activity.CRISPRDetect: A flexible algorithm to define CRISPR arrays.Casposon integration shows strong target site preference and recapitulates protospacer integration by CRISPR-Cas systemsCasposons: mobile genetic elements that gave rise to the CRISPR-Cas adaptation machinery.Highly efficient primed spacer acquisition from targets destroyed by the Escherichia coli type I-E CRISPR-Cas interfering complexMolecular recordings by directed CRISPR spacer acquisition.Altered stoichiometry Escherichia coli Cascade complexes with shortened CRISPR RNA spacers are capable of interference and primed adaptation.The expanding footprint of CRISPR/Cas9 in the plant sciences.The CRISPR-Cas9 system in Neisseria spp.CRISPR-Cas: Adapting to change.A decade of discovery: CRISPR functions and applications.Conformational regulation of CRISPR-associated nucleases.Type III CRISPR-Cas systems can provide redundancy to counteract viral escape from type I systems.Structures of the CRISPR genome integration complex.United we stand: big roles for small RNA gene clusters.Protecting genome integrity during CRISPR immune adaptation.Asymmetric positioning of Cas1-2 complex and Integration Host Factor induced DNA bending guide the unidirectional homing of protospacer in CRISPR-Cas type I-E system.Repeat Size Determination by Two Molecular Rulers in the Type I-E CRISPR Array.Interference-driven spacer acquisition is dominant over naive and primed adaptation in a native CRISPR-Cas system.Conformational Control of Cascade Interference and Priming Activities in CRISPR ImmunityCRISPR-Cas adaptive immunity and the three Rs.Memory Upgrade: Insights into Primed Adaptation by CRISPR-Cas Immune Systems.Spacer capture and integration by a type I-F Cas1-Cas2-3 CRISPR adaptation complex.Prespacer processing and specific integration in a Type I-A CRISPR system.Class 2 CRISPR-Cas RNA-guided endonucleases: Swiss Army knives of genome editing.How type II CRISPR-Cas establish immunity through Cas1-Cas2-mediated spacer integration.Role of free DNA ends and protospacer adjacent motifs for CRISPR DNA uptake in Pyrococcus furiosus.Priming in a permissive type I-C CRISPR-Cas system reveals distinct dynamics of spacer acquisition and loss.Crystal-clear memories of a bacterium.Cas4-Dependent Prespacer Processing Ensures High-Fidelity Programming of CRISPR Arrays.
P2860
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P2860
Foreign DNA capture during CRISPR-Cas adaptive immunity.
description
2015 nî lūn-bûn
@nan
2015 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Foreign DNA capture during CRISPR-Cas adaptive immunity.
@ast
Foreign DNA capture during CRISPR-Cas adaptive immunity.
@en
Foreign DNA capture during CRISPR-Cas adaptive immunity.
@nl
type
label
Foreign DNA capture during CRISPR-Cas adaptive immunity.
@ast
Foreign DNA capture during CRISPR-Cas adaptive immunity.
@en
Foreign DNA capture during CRISPR-Cas adaptive immunity.
@nl
prefLabel
Foreign DNA capture during CRISPR-Cas adaptive immunity.
@ast
Foreign DNA capture during CRISPR-Cas adaptive immunity.
@en
Foreign DNA capture during CRISPR-Cas adaptive immunity.
@nl
P2093
P2860
P356
P1433
P1476
Foreign DNA capture during CRISPR-Cas adaptive immunity.
@en
P2093
Alan N Engelman
James K Nuñez
Lucas B Harrington
Philip J Kranzusch
P2860
P2888
P304
P356
10.1038/NATURE15760
P407
P577
2015-10-21T00:00:00Z
P6179
1025388189