Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism.
about
The dark matter of the cancer genome: aberrations in regulatory elements, untranslated regions, splice sites, non-coding RNA and synonymous mutationsNeuroblastoma: oncogenic mechanisms and therapeutic exploitation of necroptosisTranscriptional Dynamics at Brain Enhancers: from Functional Specialization to NeurodegenerationNeuroblastoma, a Paradigm for Big Data Science in Pediatric Oncology.The burden of childhood cancer in Mexico: Implications for low- and middle-income countries.Role of non-coding sequence variants in cancer.Evolving landscape of tumor molecular profiling for personalized cancer therapy: a comprehensive review.Tissue-specific tumorigenesis: context matters.Common variants upstream of MLF1 at 3q25 and within CPZ at 4p16 associated with neuroblastoma.Common genetic variants associated with telomere length confer risk for neuroblastoma and other childhood cancersTAD disruption as oncogenic driver.Exploiting the Epigenome to Control Cancer-Promoting Gene-Expression Programs.LMO1 gene polymorphisms contribute to decreased neuroblastoma susceptibility in a Southern Chinese population.Genome-wide compendium and functional assessment of in vivo heart enhancers.Loss of EGFR-ASAP1 signaling in metastatic and unresectable hepatoblastoma.Deregulation of polycomb repressor complex 1 modifier AUTS2 in T-cell leukemia.Making sense of the cause of Crohn's - a new look at an old disease.Common variations within HACE1 gene and neuroblastoma susceptibility in a Southern Chinese population.Small genomic insertions form enhancers that misregulate oncogenesThe Genomic Impact of DNA CpG Methylation on Gene Expression; Relationships in Prostate CancerAdvances in the translational genomics of neuroblastoma: From improving risk stratification and revealing novel biology to identifying actionable genomic alterations.Computational Prediction of Position Effects of Apparently Balanced Human Chromosomal Rearrangements.The functional variant rs34330 of CDKN1B is associated with risk of neuroblastoma.Neuroblastoma in children: Update on clinicopathologic and genetic prognostic factors.The cancer epigenome: Concepts, challenges, and therapeutic opportunities.Enhancer deregulation in cancer and other diseases.Altered TERT promoter and other genomic regulatory elements: occurrence and impact.ChIP-seq in studying epigenetic mechanisms of disease and promoting precision medicine: progresses and future directions.Emergence of the Noncoding Cancer Genome: A Target of Genetic and Epigenetic Alterations.Alternative intronic promoters in development and disease.Genomic Alterations of Non-Coding Regions Underlie Human Cancer: Lessons from T-ALL.Genetic susceptibility to neuroblastoma.Super-Enhancer-Driven Transcriptional Dependencies in Cancer.Associations between LMO1 gene polymorphisms and Wilms' tumor susceptibility.APOBEC signature mutation generates an oncogenic enhancer that drives LMO1 expression in T-ALLGeneHancer: genome-wide integration of enhancers and target genes in GeneCards.Incorporating genomic, transcriptomic and clinical data: a prognostic and stem cell-like MYC and PRC imbalance in high-risk neuroblastoma.LMO1 polymorphisms reduce neuroblastoma risk in Chinese children: a two-center case-control study.Systematic identification of regulatory variants associated with cancer risk.Transcription instability in high-risk neuroblastoma is associated with a global perturbation of chromatin domains.
P2860
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P2860
Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism.
description
2015 nî lūn-bûn
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2015 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism.
@ast
Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism.
@en
Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism.
@nl
type
label
Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism.
@ast
Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism.
@en
Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism.
@nl
prefLabel
Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism.
@ast
Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism.
@en
Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism.
@nl
P2093
P2860
P50
P356
P1433
P1476
Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism
@en
P2093
A Thomas Look
Achille Iolascon
Andrew C Wood
Cynthia Winter
Daniela S Gerhard
Derek A Oldridge
Hakon Hakonarson
Ian Crimmins
Jaime M Guidry Auvil
Javed Khan
P2860
P2888
P304
P356
10.1038/NATURE15540
P407
P577
2015-11-11T00:00:00Z