MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism.
about
Emerging functions of the Quaking RNA-binding proteins and link to human diseasesMolecular Testing of Brain Tumor.Qki deficiency maintains stemness of glioma stem cells in suboptimal environment by downregulating endolysosomal degradation.Tyrosine receptor kinase B is a drug target in astrocytomas.Functional interrogation of non-coding DNA through CRISPR genome editing.Exploiting molecular biology for diagnosis and targeted management of pediatric low-grade gliomas.Adenoid cystic carcinoma: emerging role of translocations and gene fusionsPolymorphous low-grade neuroepithelial tumor of the young (PLNTY): an epileptogenic neoplasm with oligodendroglioma-like components, aberrant CD34 expression, and genetic alterations involving the MAP kinase pathway.CRAF gene fusions in pediatric low-grade gliomas define a distinct drug response based on dimerization profiles.Statistical algorithms improve accuracy of gene fusion detection.RNA-binding protein QKI-5 inhibits the proliferation of clear cell renal cell carcinoma via post-transcriptional stabilization of RASA1 mRNASam68 functions as a transcriptional coactivator of the p53 tumor suppressor.Advances in the molecular genetics of gliomas - implications for classification and therapy.Pediatric low-grade gliomas: implications of the biologic era.Recent Advances on the Molecular Pathology of Glial Neoplasms in Children and Adults.Splicing-factor alterations in cancers.An integrative molecular and genomic analysis of pediatric hemispheric low-grade gliomas: an update.Emergence of the Noncoding Cancer Genome: A Target of Genetic and Epigenetic Alterations.MYB-QKI drives childhood brain tumors via tripartite mechanism.A comprehensive review of paediatric low-grade diffuse glioma: pathology, molecular genetics and treatment.Characterization of gliomas: from morphology to molecules.MYB deregulation from a EWSR1-MYB fusion at leukemic evolution of a JAK2 (V617F) positive primary myelofibrosis.Therapeutic radiation for childhood cancer drives structural aberrations of NF2 in meningiomas.Angiocentric glioma with MYB-QKI fusion located in the brainstem, rather than cerebral cortex.Overcoming resistance to single-agent therapy for oncogenic BRAF gene fusions via combinatorial targeting of MAPK and PI3K/mTOR signaling pathways.Comprehensive Genomic Profiling of 282 Pediatric Low- and High-Grade Gliomas Reveals Genomic Drivers, Tumor Mutational Burden, and Hypermutation Signatures.Pediatric Low-Grade Gliomas: Next Biologically Driven Steps.Clinical and molecular insights into adenoid cystic carcinoma: Neural crest‐like stemness as a target.DiseaseEnhancer: a resource of human disease-associated enhancer catalog.Roles of microRNAs and RNA-Binding Proteins in the Regulation of Colorectal Cancer Stem Cells.Somatic Superenhancer Duplications and Hotspot Mutations Lead to Oncogenic Activation of the KLF5 Transcription Factor.Emerging Opportunities for Target Discovery in Rare Cancers.Clinical and molecular insights into adenoid cystic carcinoma: Neural crest-like stemness as a target.Copy number alterations unmasked as enhancer hijackers.Brainstem angiocentric gliomas with MYB-QKI rearrangements.Clinical targeted exome-based sequencing in combination with genome-wide copy number profiling: precision medicine analysis of 203 pediatric brain tumors.Recurrent MYB rearrangement in blastic plasmacytoid dendritic cell neoplasm.Editorial: Targeting MYB Oncogene Expression in Adenoid Cystic Carcinoma.Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling.Alternative-splicing defects in cancer: Splicing regulators and their downstream targets, guiding the way to novel cancer therapeutics.
P2860
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P2860
MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism.
description
2016 nî lūn-bûn
@nan
2016 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
MYB-QKI rearrangements in angi ...... hrough a tripartite mechanism.
@ast
MYB-QKI rearrangements in angi ...... hrough a tripartite mechanism.
@en
MYB-QKI rearrangements in angi ...... hrough a tripartite mechanism.
@nl
type
label
MYB-QKI rearrangements in angi ...... hrough a tripartite mechanism.
@ast
MYB-QKI rearrangements in angi ...... hrough a tripartite mechanism.
@en
MYB-QKI rearrangements in angi ...... hrough a tripartite mechanism.
@nl
prefLabel
MYB-QKI rearrangements in angi ...... hrough a tripartite mechanism.
@ast
MYB-QKI rearrangements in angi ...... hrough a tripartite mechanism.
@en
MYB-QKI rearrangements in angi ...... hrough a tripartite mechanism.
@nl
P2093
P2860
P50
P356
P1433
P1476
MYB-QKI rearrangements in angi ...... hrough a tripartite mechanism.
@en
P2093
Adam A Tracy
Adam C Resnick
Almos Klekner
Alon Goren
Amanda Silva
Angela J Waanders
Anna Maria Buccoliero
Azra H Ligon
Brenton R Paolella
Caterina Giannini
P2860
P2888
P304
P356
10.1038/NG.3500
P407
P50
P577
2016-02-01T00:00:00Z