Behavioral and neurochemical interactions between Group 1 mGluR antagonists and ethanol: potential insight into their anti-addictive properties.
about
Glutamatergic substrates of drug addiction and alcoholismmGluR5 antagonism attenuates methamphetamine reinforcement and prevents reinstatement of methamphetamine-seeking behavior in ratsNegative Allosteric Modulators of Metabotropic Glutamate Receptors Subtype 5 in Addiction: a Therapeutic WindowGlutamatergic targets for new alcohol medicationsRole of cues and contexts on drug-seeking behaviourThe metabotropic glutamate 5 receptor modulates extinction and reinstatement of methamphetamine-seeking in miceDifferential effects of chronic ethanol consumption and withdrawal on homer/glutamate receptor expression in subregions of the accumbens and amygdala of P ratsEthanol-Associated Changes in Glutamate Reward Neurocircuitry: A Minireview of Clinical and Preclinical Genetic Findings.Homers regulate drug-induced neuroplasticity: implications for addictionIntermittent high-dose ethanol exposures increase motivation for operant ethanol self-administration: possible neurochemical mechanism.Interoceptive effects of alcohol require mGlu5 receptor activity in the nucleus accumbensMetabotropic glutamate receptor 5 activity in the nucleus accumbens is required for the maintenance of ethanol self-administration in a rat genetic model of high alcohol intakeEffects of the mGlu2/3 agonist LY379268 and the mGlu5 antagonist MTEP on ethanol seeking and reinforcement are differentially altered in rats with a history of ethanol dependenceCognitive effects of Group I metabotropic glutamate receptor ligands in the context of drug addiction.3-Cyano-5-fluoro-N-arylbenzamides as negative allosteric modulators of mGlu(5): Identification of easily prepared tool compounds with CNS exposure in rats.How adaptation of the brain to alcohol leads to dependence: a pharmacological perspective.The metabotropic glutamate receptor subtype 5 mediates sensitivity to the sedative properties of ethanol.Assessment of GABA-B, metabotropic glutamate, and opioid receptor involvement in an animal model of binge drinkingContribution of early environmental stress to alcoholism vulnerability.mGlu5 receptors are involved in the discriminative stimulus effects of self-administered ethanol in ratsRecent advances in the design and development of novel negative allosteric modulators of mGlu(5)Therapeutic potential of metabotropic glutamate receptor modulators.Frequency of alcohol consumption in humans; the role of metabotropic glutamate receptors and downstream signaling pathwaysChanges in extracellular levels of glutamate in the nucleus accumbens after ethanol-induced behavioral sensitization in adolescent and adult mice.Ethanol up-regulates nucleus accumbens neuronal activity dependent pentraxin (Narp): implications for alcohol-induced behavioral plasticity.mGlu receptors and drug addiction.Nucleus accumbens mGluR5-associated signaling regulates binge alcohol drinking under drinking-in-the-dark procedures.Homer2 regulates alcohol and stress cross-sensitization.Antagonism of metabotropic glutamate 1 receptors attenuates behavioral effects of cocaine and methamphetamine in squirrel monkeys.Rodent models and mechanisms of voluntary binge-like ethanol consumption: Examples, opportunities, and strategies for preclinical research.Role of the serotonergic system in alcohol dependence: from animal models to clinics.Effects of mGlu1-receptor blockade on ethanol self-administration in inbred alcohol-preferring rats.Levetiracetam has opposite effects on alcohol- and cocaine-related behaviors in C57BL/6J mice.Regulation of motivation to self-administer ethanol by mGluR5 in alcohol-preferring (P) rats.Differential modulation of ethanol-induced sedation and hypnosis by metabotropic glutamate receptor antagonists in C57BL/6J mice.Metabotropic glutamate receptor 5 (mGluR5) regulation of ethanol sedation, dependence and consumption: relationship to acamprosate actionsMetabotropic glutamate receptor ligands as potential therapeutics for addictionThe Effect of mGluR5 Antagonism During Binge Drinkingon Subsequent Ethanol Intake in C57BL/6J Mice: Sex- and Age-Induced DifferencesPrenatal stress enhances responsiveness to cocaine.Binge drinking upregulates accumbens mGluR5-Homer2-PI3K signaling: functional implications for alcoholism.
P2860
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P2860
Behavioral and neurochemical interactions between Group 1 mGluR antagonists and ethanol: potential insight into their anti-addictive properties.
description
2006 nî lūn-bûn
@nan
2006 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Behavioral and neurochemical i ...... eir anti-addictive properties.
@ast
Behavioral and neurochemical i ...... eir anti-addictive properties.
@en
Behavioral and neurochemical i ...... eir anti-addictive properties.
@nl
type
label
Behavioral and neurochemical i ...... eir anti-addictive properties.
@ast
Behavioral and neurochemical i ...... eir anti-addictive properties.
@en
Behavioral and neurochemical i ...... eir anti-addictive properties.
@nl
prefLabel
Behavioral and neurochemical i ...... eir anti-addictive properties.
@ast
Behavioral and neurochemical i ...... eir anti-addictive properties.
@en
Behavioral and neurochemical i ...... eir anti-addictive properties.
@nl
P2093
P1476
Behavioral and neurochemical i ...... heir anti-addictive properties
@en
P2093
Cole Patterson
Karen K Szumlinski
Lawrence D Middaugh
Reem A Hannun
Zuzana Kapasova
P304
P356
10.1016/J.DRUGALCDEP.2006.04.003
P577
2006-05-11T00:00:00Z