about
Asparagine requirement in Plasmodium berghei as a target to prevent malaria transmission and liver infections.Free Glycine Accelerates the Autoproteolytic Activation of Human AsparaginaseEnhanced oxidative stress resistance through activation of a zinc deficiency transcription factor in Brachypodium distachyonDeficiency of asparagine synthetase causes congenital microcephaly and a progressive form of encephalopathy.An artifact in LC-MS/MS measurement of glutamine and glutamic acid: in-source cyclization to pyroglutamic acid.A conserved glutamate controls the commitment to acyl-adenylate formation in asparagine synthetaseAsparagine synthetase: regulation by cell stress and involvement in tumor biologyCharacterization of FdmV as an amide synthetase for fredericamycin A biosynthesis in Streptomyces griseus ATCC 43944.GFP reporter screens for the engineering of amino acid degrading enzymes from libraries expressed in bacteria.An inhibitor of human asparagine synthetase suppresses proliferation of an L-asparaginase-resistant leukemia cell line.Metabolomics of the tumor microenvironment in pediatric acute lymphoblastic leukemia.Identification and functional characterization of a novel bacterial type asparagine synthetase A: a tRNA synthetase paralog from Leishmania donovaniMesenchymal cells regulate the response of acute lymphoblastic leukemia cells to asparaginase.Cell intrinsic and extrinsic activators of the unfolded protein response in cancer: Mechanisms and targets for therapyATF5 polymorphisms influence ATF function and response to treatment in children with childhood acute lymphoblastic leukemia.Transcriptomics of liver and muscle in Holstein cows genetically divergent for fertility highlight differences in nutrient partitioning and inflammation processes.Functional genomic screening reveals asparagine dependence as a metabolic vulnerability in sarcomaIntegrative molecular profiling reveals asparagine synthetase is a target in castration-resistant prostate cancer.L-asparaginase-induced pancreatic injury is associated with an imbalance in plasma amino acid levels.Eukaryotic initiation factor 2 phosphorylation and translational control in metabolism.Asparagine synthetase is an independent predictor of surgical survival and a potential therapeutic target in hepatocellular carcinomaGeneral control nonderepressible 2 deletion predisposes to asparaginase-associated pancreatitis in mice.The eukaryotic initiation factor 2 kinase GCN2 protects against hepatotoxicity during asparaginase treatment.Metabolic Alterations Caused by KRAS Mutations in Colorectal Cancer Contribute to Cell Adaptation to Glutamine Depletion by Upregulation of Asparagine Synthetase.Optimized CGenFF force-field parameters for acylphosphate and N-phosphonosulfonimidoyl functional groups.Targeting arginine-dependent cancers with arginine-degrading enzymes: opportunities and challenges.Mitochondria as biosynthetic factories for cancer proliferation.A critical review on properties and applications of microbial l-asparaginases.Asparagine Metabolic Pathways in Arabidopsis.Therapeutic l-asparaginase: upstream, downstream and beyond.Targeting metabolic reprogramming in KRAS-driven cancers.Tumour-specific proline vulnerability uncovered by differential ribosome codon reading.Glutaminase activity determines cytotoxicity of L-asparaginases on most leukemia cell lines.Knockdown of asparagine synthetase by RNAi suppresses cell growth in human melanoma cells and epidermoid carcinoma cells.Differential mechanisms of asparaginase resistance in B-type acute lymphoblastic leukemia and malignant natural killer cell linesPharmacology, immunogenicity, and efficacy of a novel pegylated recombinant Erwinia chrysanthemi-derived L-asparaginase.Down-regulation of asparagine synthetase induces cell cycle arrest and inhibits cell proliferation of breast cancer.Asparagine depletion potentiates the cytotoxic effect of chemotherapy against brain tumors.Expression of asparagine synthetase predicts in vitro response to L-asparaginase in canine lymphoid cell lines.A conserved tyrosyl-glutamyl catalytic dyad in evolutionarily linked enzymes: carbapenam synthetase and beta-lactam synthetase.
P2860
Q27319073-CE1316DE-C7EC-49C9-9E62-DE6FD55BA9C4Q27677456-E15D724A-F25E-4856-8417-16E418D56506Q28397424-867006F1-0889-42FE-8136-C88A8EA6D0FFQ30557070-67F6209C-5F78-4B0C-9CB4-286708390D09Q33777165-CB8C5AC1-3F9E-4785-986A-77032BFD9D62Q34284425-7DBEC855-4C37-4BAD-BEBF-120D9A5053D4Q34327474-AB7E3638-52EF-4DE8-90F8-8902A7A8830DQ34385755-F406F3B8-64FA-4848-BB24-B0B80C08AFE5Q34592385-C57FC49D-ECE8-4FAE-874C-58099663C080Q34653242-661FB76F-9386-4635-85B6-78CDC12FF068Q35070594-AA5EE5D4-FF0C-45A4-81A6-F21537297EE4Q35115121-C1D4B7E5-8FF7-42AF-8326-4B9A72927C0BQ35677647-1BA708F4-45AD-454C-8445-740C84685121Q35912293-57C97092-75C6-46A1-8641-1C8B6476FFC2Q35930217-DA83662F-ECB2-43EB-BE0A-622E777555E8Q36101702-20509317-3AFB-4296-A459-175EE8EEF64BQ36415118-A80CB802-AB77-4BEA-BB93-FA556C3E513EQ36468744-CE919639-EAE1-4A5D-9453-0E4085CC09E4Q36649984-8589E3B2-95C2-45F6-94D4-D3E827CCF680Q36830383-91FE5102-1C5B-4622-8BD1-41B350E0D442Q37003403-C5D1D70E-A71D-4181-8953-3D43B58FEB35Q37071811-93B03702-3C20-413E-A6B9-ED51985CC02FQ37341948-F1096CF6-C222-4DC4-A0F7-07D4DBFFE746Q37352111-EBA8A40B-B58E-4FF1-8E2C-8F155C4D331EQ37524043-BFB3F3A2-4C0E-400D-A458-AF613BFD0D9DQ38181070-57932E33-FB87-4D2E-B04B-20EA4EE0134FQ38332527-8C2A6786-2AC4-4485-ADC6-92D0E0C5E563Q38417141-64DB88FB-9D3E-430D-939D-4D037D054C75Q38656318-9B88DA65-1014-4E92-B53E-CB3554212625Q38676439-5FE5AD9E-1CBF-45BA-AB75-C0612D5CF770Q38710288-BCB4CAD6-84CF-4BEF-B366-641FB0D25D0FQ38794075-3C7431D0-D903-4D07-A07B-622ECFFE2C84Q38879052-4854B0A8-E7D7-4F33-8624-CD72B17606A1Q38889172-F89F40CD-E68D-4F39-8402-D77FA75CDCC8Q38915906-5DBFE50F-7AA8-4AB8-86C2-959266121AC1Q38994917-9A99E1AD-3EC0-4CBB-86D5-5CD5E171FBCCQ39000725-8CCB1367-486D-4B21-B1E6-046CF4AFAA35Q39026261-06248E75-CC9A-4478-AD9D-688062490057Q39096462-FF096AAB-DE81-4476-B34B-97C696057C88Q39441324-9E700AAA-DD28-4F00-AE89-DFA6C5842597
P2860
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Asparagine synthetase chemotherapy.
@ast
Asparagine synthetase chemotherapy.
@en
Asparagine synthetase chemotherapy.
@nl
type
label
Asparagine synthetase chemotherapy.
@ast
Asparagine synthetase chemotherapy.
@en
Asparagine synthetase chemotherapy.
@nl
prefLabel
Asparagine synthetase chemotherapy.
@ast
Asparagine synthetase chemotherapy.
@en
Asparagine synthetase chemotherapy.
@nl
P2860
P1476
Asparagine synthetase chemotherapy.
@en
P2093
Michael S Kilberg
Nigel G J Richards
P2860
P304
P356
10.1146/ANNUREV.BIOCHEM.75.103004.142520
P577
2006-01-01T00:00:00Z