Translocation of molecules into cells by pH-dependent insertion of a transmembrane helix.
about
Mechanism and uses of a membrane peptide that targets tumors and other acidic tissues in vivoControlled delivery of bioactive molecules into live cells using the bacterial mechanosensitive channel MscL.Acidic pH-targeted chitosan capped mesoporous silica coated gold nanorods facilitate detection of pancreatic tumors via multispectral optoacoustic tomographyTargeting acidic diseased tissue: New technology based on use of the pH (Low) Insertion Peptide (pHLIP).Accurate analysis of tumor margins using a fluorescent pH Low Insertion Peptide (pHLIP)pH (low) insertion peptide (pHLIP) inserts across a lipid bilayer as a helix and exits by a different path.Aspartate embedding depth affects pHLIP's insertion pKa.Tuning the insertion properties of pHLIP.Insertion into lipid bilayer of truncated pHLIP®peptide.Heterogeneous diffusion of a membrane-bound pHLIP peptide.pH-(low)-insertion-peptide (pHLIP) translocation of membrane impermeable phalloidin toxin inhibits cancer cell proliferation.pHLIP-FIRE, a cell insertion-triggered fluorescent probe for imaging tumors demonstrates targeted cargo delivery in vivo.Family of pH (low) insertion peptides for tumor targeting.Mapping the homodimer interface of an optimized, artificial, transmembrane protein activator of the human erythropoietin receptor.MicroRNA silencing for cancer therapy targeted to the tumour microenvironment.Roles of carboxyl groups in the transmembrane insertion of peptidesOptical molecular imaging detects changes in extracellular pH with the development of head and neck cancer.Measuring tumor aggressiveness and targeting metastatic lesions with fluorescent pHLIP.pH-controlled delivery of luminescent europium coated nanoparticles into platelets.Inhibition of cancer cell proliferation and breast tumor targeting of pHLIP-monomethyl auristatin E conjugates.Modulation of the pHLIP transmembrane helix insertion pathway.Residue-specific structures and membrane locations of pH-low insertion peptide by solid-state nuclear magnetic resonanceThe pH low insertion peptide pHLIP Variant 3 as a novel marker of acidic malignant lesionsA monomeric membrane peptide that lives in three worlds: in solution, attached to, and inserted across lipid bilayers.Unassisted translocation of large polypeptide domains across phospholipid bilayersStimuli-responsive nanoparticles for targeting the tumor microenvironment.Triple stimulus-responsive polypeptide nanoparticles that enhance intratumoral spatial distribution.Advanced targeted nanomedicinepH-sensitive membrane peptides (pHLIPs) as a novel class of delivery agents.pHLIP-mediated targeting of truncated tissue factor to tumor vessels causes vascular occlusion and impairs tumor growthpH (low) insertion peptide (pHLIP) targets ischemic myocardium.pHLIP peptide targets nanogold particles to tumorsMyristoyl-based transport of peptides into living cells.Bilayer interactions of pHLIP, a peptide that can deliver drugs and target tumorsPeptide targeting and imaging of damaged lung tissue in influenza-infected miceEnergetics of peptide (pHLIP) binding to and folding across a lipid bilayer membrane.pH-Selective Cytotoxicity of pHLIP-Antimicrobial Peptide Conjugates.Membrane binding and insertion of a pHLIP peptide studied by all-atom molecular dynamics simulations.Probe for the measurement of cell surface pH in vivo and ex vivo.A novel technology for the imaging of acidic prostate tumors by positron emission tomography.
P2860
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P2860
Translocation of molecules into cells by pH-dependent insertion of a transmembrane helix.
description
2006 nî lūn-bûn
@nan
2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Translocation of molecules into cells by pH-dependent insertion of a transmembrane helix.
@ast
Translocation of molecules into cells by pH-dependent insertion of a transmembrane helix.
@en
Translocation of molecules into cells by pH-dependent insertion of a transmembrane helix.
@nl
type
label
Translocation of molecules into cells by pH-dependent insertion of a transmembrane helix.
@ast
Translocation of molecules into cells by pH-dependent insertion of a transmembrane helix.
@en
Translocation of molecules into cells by pH-dependent insertion of a transmembrane helix.
@nl
prefLabel
Translocation of molecules into cells by pH-dependent insertion of a transmembrane helix.
@ast
Translocation of molecules into cells by pH-dependent insertion of a transmembrane helix.
@en
Translocation of molecules into cells by pH-dependent insertion of a transmembrane helix.
@nl
P2093
P2860
P356
P1476
Translocation of molecules into cells by pH-dependent insertion of a transmembrane helix.
@en
P2093
Donald M Engelman
Oleg A Andreev
Ursula Lehnert
Yana K Reshetnyak
P2860
P304
P356
10.1073/PNAS.0601463103
P407
P577
2006-04-11T00:00:00Z