Metabolic control analysis in drug discovery and disease. - Test2 - elhamkhani - TriplyDB

Metabolic control analysis in drug discovery and disease.

Metabolic control analysis in drug discovery and disease.

http://www.wikidata.org/entity/Q34550535

about

Functional analysis of disease-causing mutations in human galactokinase Stable isotope-resolved metabolomics and applications for drug development A medical nutriment has supportive value in the treatment of colorectal cancer Metabolic control analysis in a cellular model of elevated MAO-B: relevance to Parkinson's disease Synthetic biology and regulatory networks: where metabolic systems biology meets control engineering Plant metabolic modeling: achieving new insight into metabolism and metabolic engineering Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review Standardizing the experimental conditions for using urine in NMR-based metabolomic studies with a particular focus on diagnostic studies: a review Patterns of metabolite changes identified from large-scale gene perturbations in Arabidopsis using a genome-scale metabolic network Bioinformatic Analysis of Leishmania donovani Long-Chain Fatty Acid-CoA Ligase as a Novel Drug Target Metabolic investigation of host/pathogen interaction using MS2-infected Escherichia coli Mass spectrometry based cellular phosphoinositides profiling and phospholipid analysis: a brief review Phosphoproteomics data classify hematological cancer cell lines according to tumor type and sensitivity to kinase inhibitors Integrating gene and protein expression data with genome-scale metabolic networks to infer functional pathways Making life difficult for Clostridium difficile: augmenting the pathogen's metabolic model with transcriptomic and codon usage data for better therapeutic target characterization Incorporation of enzyme concentrations into FBA and identification of optimal metabolic pathways.Submolecular regulation of cell transformation by deuterium depleting water exchange reactions in the tricarboxylic acid substrate cycle.Genome-scale metabolic analysis of Clostridium thermocellum for bioethanol production.Modeling core metabolism in cancer cells: surveying the topology underlying the Warburg effect.Protein network prediction and topological analysis in Leishmania major as a tool for drug target selection.Cross-species proteomics reveals specific modulation of signaling in cancer and stromal cells by phosphoinositide 3-kinase (PI3K) inhibitors Methanol assimilation in Methylobacterium extorquens AM1: demonstration of all enzymes and their regulation.Inverted-U-shaped correlation between dopamine receptor availability in striatum and sensation seeking.Two-stage flux balance analysis of metabolic networks for drug target identification.Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step.Metabolic control analysis under uncertainty: framework development and case studies Fructose impairs glucose-induced hepatic triglyceride synthesis.Genomics, proteomics: what's next?Reconstruction and analysis of human kidney-specific metabolic network based on omics data.Analysis of signaling networks distributed over intracellular compartments based on protein-protein interactions Exploring the Altered Dynamics of Mammalian Central Carbon Metabolic Pathway in Cancer Cells: A Classical Control Theoretic Approach.Analyzing the biology on the system level.Metabolic engineering in the -omics era: elucidating and modulating regulatory networks.Metabolomic approaches to phenotype characterization and applications to complex diseases.Amino Acids Rather than Glucose Account for the Majority of Cell Mass in Proliferating Mammalian Cells.Advanced stoichiometric analysis of metabolic networks of mammalian systems.Global metabolic profiling and its role in systems biology to advance personalized medicine in the 21st century.Intelligently deciphering unintelligible designs: algorithmic algebraic model checking in systems biology Δ1-pyrroline-5-carboxylate reductase as a new target for therapeutics: inhibition of the enzyme from Streptococcus pyogenes and effects in vivo Dynamic modeling and analysis of cancer cellular network motifs.

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Metabolic control analysis in drug discovery and disease.

http://www.wikidata.org/entity/Q34550535

description

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2002 թվականի մարտին հրատարակված գիտական հոդված

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2002年の論文

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Metabolic control analysis in drug discovery and disease.

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P1433

Nature Biotechnology

P1476

Metabolic control analysis in drug discovery and disease.

@en

P2093

Josep J Centelles

http://www.w3.org/2001/XMLSchema#string

Laszlo G Boros

http://www.w3.org/2001/XMLSchema#string

Paul W-N Lee

http://www.w3.org/2001/XMLSchema#string

P2860

Impaired hepatic glycogen synthesis in glucokinase-deficient (MODY-2) subjects

How aneuploidy affects metabolic control and causes cancer

On the Origin of Cancer Cells

A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations

What do mitochondrial diseases teach us about normal mitochondrial functions...that we already knew: threshold expression of mitochondrial defects.

Detection of elementary flux modes in biochemical networks: a promising tool for pathway analysis and metabolic engineering.

Oncogenic alterations of metabolism.

Metabolic engineering: techniques for analysis of targets for genetic manipulations.

Genomic biology.

Complexity in biological signaling systems.

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243-249

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scholarly article

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10.1038/NBT0302-243

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3

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20

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Marta Cascante Serratosa

Pedro de Atauri

Begoña Comin-Anduix

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2002-03-01T00:00:00Z

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11488059

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11875424

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