Cyclodextrin-based pharmaceutics: past, present and future. - Test2 - elhamkhani - TriplyDB

Cyclodextrin-based pharmaceutics: past, present and future.

Cyclodextrin-based pharmaceutics: past, present and future.

http://www.wikidata.org/entity/Q34552997

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Supramolecular Complexation of Carbohydrates for the Bioavailability Enhancement of Poorly Soluble Drugs siRNA Versus miRNA as Therapeutics for Gene Silencing Obstructing toxin pathways by targeted pore blockage Collaborative development of 2-hydroxypropyl-β-cyclodextrin for the treatment of Niemann-Pick type C1 disease Molecular mechanism of cyclodextrin mediated cholesterol extraction Structural basis for cyclodextrin recognition by Thermoactinomyces vulgaris cyclo/maltodextrin-binding protein Cyclodextrins as Emerging Therapeutic Tools in the Treatment of Cholesterol-Associated Vascular and Neurodegenerative Diseases RNA interference-based nanosystems for inflammatory bowel disease therapy Progress toward in vivo use of siRNAs-II Membrane cholesterol regulates lysosome-plasma membrane fusion events and modulates Trypanosoma cruzi invasion of host cells Synthesis and biological evaluation of novel folic acid receptor-targeted, β-cyclodextrin-based drug complexes for cancer treatment Oral delivery of lipophilic drugs: the tradeoff between solubility increase and permeability decrease when using cyclodextrin-based formulations Genetic and chemical activation of TFEB mediates clearance of aggregated α-synuclein Reducing Both Pgp Overexpression and Drug Efflux with Anti-Cancer Gold-Paclitaxel Nanoconjugates Potential and utilization of thermophiles and thermostable enzymes in biorefining Rapid Exchange Between Free and Bound States in RNA-Dendrimer Polyplexes: Implications on the Mechanism of Delivery and Release Polymeric nucleic acid vehicles exploit active interorganelle trafficking mechanisms.Agglomerated oral dosage forms of artemisinin/β-cyclodextrin spray-dried primary microparticles showing increased dissolution rate and bioavailability.Host-guest inclusion system of scutellarein with 2-hydroxypropyl-beta-cyclodextrin: preparation, characterization, and anticancer activity.Staudinger ligation towards cyclodextrin dimers in aqueous/organic media. Synthesis, conformations and guest-encapsulation ability.Development and evaluation of orally disintegrating tablets of cilostazol-β-cyclodextrin inclusion complexes.Inclusion complex of a new propiconazole derivative with β-cyclodextrin: NMR, ESI-MS and preliminary pharmacological studies.Steric Constraints Induced Frustrated Growth of Supramolecular Nanorods in Water.The influence of polymer topology on pharmacokinetics: differences between cyclic and linear PEGylated poly(acrylic acid) comb polymers Beta-cyclodextrin-centered star-shaped amphiphilic polymers for doxorubicin delivery.Host-guest complexation studied by fluorescence correlation spectroscopy: adamantane-cyclodextrin inclusion Polymeric Materials for Gene Delivery and DNA Vaccination A targeted nanoglobular contrast agent from host-guest self-assembly for MR cancer molecular imaging.Endocytosis of beta-cyclodextrins is responsible for cholesterol reduction in Niemann-Pick type C mutant cells.Precision studies in supramolecular chemistry: a 1H NMR study of hydroxymethoxyacetophenone/β-cyclodextrin complexes.Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles.Pharmacokinetics and pharmacodynamics of nasally delivered midazolam New formulation of an old drug in hypertension treatment: the sustained release of captopril from cyclodextrin nanoparticles.Discovery of cationic polymers for non-viral gene delivery using combinatorial approaches.Click synthesis of estradiol-cyclodextrin conjugates as cell compartment selective estrogens Blocking anthrax lethal toxin at the protective antigen channel by using structure-inspired drug design.A novel synthetic strategy for monosubstituted cyclodextrin derivatives.Cholesterol depletion by methyl-β-cyclodextrin augments tamoxifen induced cell death by enhancing its uptake in melanoma.The inhibition of anti-DNA binding to DNA by nucleic acid binding polymers.Cations in a molecular funnel: vibrational spectroscopy of isolated cyclodextrin complexes with alkali metals.

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P2860

Cyclodextrin-based pharmaceutics: past, present and future.

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Cyclodextrin-based pharmaceutics: past, present and future.

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Nature Reviews Drug Discovery

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Cyclodextrin-based pharmaceutics: past, present and future.

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Marcus E Brewster

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Mark E Davis

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P2860

A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability

Intracavernous alprostadil alfadex (EDEX/VIRIDAL) is effective and safe in patients with erectile dysfunction after failing sildenafil (Viagra)

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Axial penile rigidity as primary efficacy outcome during multi-institutional in-office dose titration clinical trials with alprostadil alfadex in patients with erectile dysfunction. Alprostadil Alfadex Study Group.

Drug carrier systems based on water-soluble cationic beta-cyclodextrin polymers.

Effects of OP-1206 alpha-CD on walking dysfunction in the rat neuropathic intermittent claudication model: comparison with nifedipine, ticlopidine and cilostazol.

Clinical evaluation, dose-finding and acceptability of AERODIOL, the pulsed estrogen therapy for treatment of climacteric symptoms.

Itraconazole: an effective oral antifungal for onychomycosis.

Intravenous itraconazole.

Itraconazole oral solution and intravenous formulations: a review of pharmacokinetics and pharmacodynamics.

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