Topical drug rescue strategy and skin protection based on the role of Mc1r in UV-induced tanning.
about
Complex signatures of selection for the melanogenic loci TYR, TYRP1 and DCT in humansBarrier requirements as the evolutionary "driver" of epidermal pigmentation in humansGenetic variants in pigmentation genes, pigmentary phenotypes, and risk of skin cancer in CaucasiansThe protective role of melanin against UV damage in human skinMelanocortin 1 Receptor: Structure, Function, and RegulationThe associations between Parkinson's disease and cancer: the plot thickensFlavonoids and Melanins: a common strategy across two kingdomsUV signaling pathways within the skinA cis-acting regulatory mutation causes premature hair graying and susceptibility to melanoma in the horseUV radiation and the skinEvidence that stress to the epidermal barrier influenced the development of pigmentation in humansIn vitro skin diffusion study of pure forskolin versus a forskolin-containing Plectranthus barbatus root extractA novel P53/POMC/Gαs/SASH1 autoregulatory feedback loop activates mutated SASH1 to cause pathologic hyperpigmentation.TRPM1 forms ion channels associated with melanin content in melanocytes.A potent activator of melanogenesis identified from small-molecule screening.Melanocyte-stimulating hormone directly enhances UV-Induced DNA repair in keratinocytes by a xeroderma pigmentosum group A-dependent mechanism.Malignant melanoma and melanocortin 1 receptor.Suppression of melanin production by expression of HSP70Substantial Effect of Melanin Influencing Factors on In vitro Melanogenesis in Muzzle Melanocytes of Differently Colored HanwooSignaling pathways in melanosome biogenesis and pathologyUnderstanding the biology of melanoma and therapeutic implicationsChemistry of mixed melanogenesis--pivotal roles of dopaquinone.Indoor ultraviolet tanning and skin cancer: health risks and opportunities.Skin β-endorphin mediates addiction to UV lightControl of melanocyte differentiation by a MITF-PDE4D3 homeostatic circuitSkin as a living coloring book: how epithelial cells create patterns of pigmentation.The Natural cAMP Elevating Compound Forskolin in Cancer Therapy: Is It Time?Stepping up melanocytes to the challenge of UV exposure.Signaling from the human melanocortin 1 receptor to ERK1 and ERK2 mitogen-activated protein kinases involves transactivation of cKIT.Melanocortin MC₁ receptor in human genetics and model systems.Ultraviolet radiation, aging and the skin: prevention of damage by topical cAMP manipulationInvestigation of the novel lead of melanocortin 1 receptor for pigmentary disorders.PKA-mediated phosphorylation of ATR promotes recruitment of XPA to UV-induced DNA damage.MC1R variants increased the risk of sporadic cutaneous melanoma in darker-pigmented Caucasians: a pooled-analysis from the M-SKIP project.A potent inhibitor of SIK2, 3, 3', 7-trihydroxy-4'-methoxyflavon (4'-O-methylfisetin), promotes melanogenesis in B16F10 melanoma cells.Defining the Contribution of MC1R Physiological Ligands to ATR Phosphorylation at Ser435, a Predictor of DNA Repair in MelanocytesGenome-wide transcriptome analysis of human epidermal melanocytes.Regulation of human skin pigmentation in situ by repetitive UV exposure: molecular characterization of responses to UVA and/or UVB.Pigment-independent cAMP-mediated epidermal thickening protects against cutaneous UV injury by keratinocyte proliferation.An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background
P2860
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P2860
Topical drug rescue strategy and skin protection based on the role of Mc1r in UV-induced tanning.
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Topical drug rescue strategy a ...... of Mc1r in UV-induced tanning.
@ast
Topical drug rescue strategy a ...... of Mc1r in UV-induced tanning.
@en
Topical drug rescue strategy a ...... of Mc1r in UV-induced tanning.
@nl
type
label
Topical drug rescue strategy a ...... of Mc1r in UV-induced tanning.
@ast
Topical drug rescue strategy a ...... of Mc1r in UV-induced tanning.
@en
Topical drug rescue strategy a ...... of Mc1r in UV-induced tanning.
@nl
prefLabel
Topical drug rescue strategy a ...... of Mc1r in UV-induced tanning.
@ast
Topical drug rescue strategy a ...... of Mc1r in UV-induced tanning.
@en
Topical drug rescue strategy a ...... of Mc1r in UV-induced tanning.
@nl
P2093
P50
P356
P1433
P1476
Topical drug rescue strategy a ...... of Mc1r in UV-induced tanning.
@en
P2093
David E Fisher
Emi K Nishimura
John A D'Orazio
Malinda Spry
Michelle Arya
Scott R Granter
Takahiro Kunisada
Tetsuji Nobuhisa
Vivien Igras
P2888
P304
P356
10.1038/NATURE05098
P407
P577
2006-09-01T00:00:00Z
P5875
P6179
1020607715