Topical drug rescue strategy and skin protection based on the role of Mc1r in UV-induced tanning. - Test2 - elhamkhani - TriplyDB

Topical drug rescue strategy and skin protection based on the role of Mc1r in UV-induced tanning.

Topical drug rescue strategy and skin protection based on the role of Mc1r in UV-induced tanning.

http://www.wikidata.org/entity/Q34567622

about

Complex signatures of selection for the melanogenic loci TYR, TYRP1 and DCT in humans Barrier requirements as the evolutionary "driver" of epidermal pigmentation in humans Genetic variants in pigmentation genes, pigmentary phenotypes, and risk of skin cancer in Caucasians The protective role of melanin against UV damage in human skin Melanocortin 1 Receptor: Structure, Function, and Regulation The associations between Parkinson's disease and cancer: the plot thickens Flavonoids and Melanins: a common strategy across two kingdoms UV signaling pathways within the skin A cis-acting regulatory mutation causes premature hair graying and susceptibility to melanoma in the horse UV radiation and the skin Evidence that stress to the epidermal barrier influenced the development of pigmentation in humans In vitro skin diffusion study of pure forskolin versus a forskolin-containing Plectranthus barbatus root extract A novel P53/POMC/Gαs/SASH1 autoregulatory feedback loop activates mutated SASH1 to cause pathologic hyperpigmentation.TRPM1 forms ion channels associated with melanin content in melanocytes.A potent activator of melanogenesis identified from small-molecule screening.Melanocyte-stimulating hormone directly enhances UV-Induced DNA repair in keratinocytes by a xeroderma pigmentosum group A-dependent mechanism.Malignant melanoma and melanocortin 1 receptor.Suppression of melanin production by expression of HSP70 Substantial Effect of Melanin Influencing Factors on In vitro Melanogenesis in Muzzle Melanocytes of Differently Colored Hanwoo Signaling pathways in melanosome biogenesis and pathology Understanding the biology of melanoma and therapeutic implications Chemistry of mixed melanogenesis--pivotal roles of dopaquinone.Indoor ultraviolet tanning and skin cancer: health risks and opportunities.Skin β-endorphin mediates addiction to UV light Control of melanocyte differentiation by a MITF-PDE4D3 homeostatic circuit Skin as a living coloring book: how epithelial cells create patterns of pigmentation.The Natural cAMP Elevating Compound Forskolin in Cancer Therapy: Is It Time?Stepping up melanocytes to the challenge of UV exposure.Signaling from the human melanocortin 1 receptor to ERK1 and ERK2 mitogen-activated protein kinases involves transactivation of cKIT.Melanocortin MC₁ receptor in human genetics and model systems.Ultraviolet radiation, aging and the skin: prevention of damage by topical cAMP manipulation Investigation of the novel lead of melanocortin 1 receptor for pigmentary disorders.PKA-mediated phosphorylation of ATR promotes recruitment of XPA to UV-induced DNA damage.MC1R variants increased the risk of sporadic cutaneous melanoma in darker-pigmented Caucasians: a pooled-analysis from the M-SKIP project.A potent inhibitor of SIK2, 3, 3', 7-trihydroxy-4'-methoxyflavon (4'-O-methylfisetin), promotes melanogenesis in B16F10 melanoma cells.Defining the Contribution of MC1R Physiological Ligands to ATR Phosphorylation at Ser435, a Predictor of DNA Repair in Melanocytes Genome-wide transcriptome analysis of human epidermal melanocytes.Regulation of human skin pigmentation in situ by repetitive UV exposure: molecular characterization of responses to UVA and/or UVB.Pigment-independent cAMP-mediated epidermal thickening protects against cutaneous UV injury by keratinocyte proliferation.An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background

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P2860

Topical drug rescue strategy and skin protection based on the role of Mc1r in UV-induced tanning.

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2006 nî lūn-bûn

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2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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David E Fisher

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