Differential var gene transcription in Plasmodium falciparum isolates from patients with cerebral malaria compared to hyperparasitaemia - Test2 - elhamkhani - TriplyDB

Differential var gene transcription in Plasmodium falciparum isolates from patients with cerebral malaria compared to hyperparasitaemia

Differential var gene transcription in Plasmodium falciparum isolates from patients with cerebral malaria compared to hyperparasitaemia

http://www.wikidata.org/entity/Q34568283

about

Immune selection and within-host competition can structure the repertoire of variant surface antigens in Plasmodium falciparum--a mathematical model Antigenic variation in Plasmodium falciparum: gene organization and regulation of the var multigene family Investigating the Pathogenesis of Severe Malaria: A Multidisciplinary and Cross-Geographical Approach The role of PfEMP1 adhesion domain classification in Plasmodium falciparum pathogenesis research Antigenic variation and the generation of diversity in malaria parasites Recent advances in malaria genomics and epigenomics The role of PfEMP1 as targets of naturally acquired immunity to childhood malaria: prospects for a vaccine G-quadruplexes in pathogens: a common route to virulence control?Expression of the domain cassette 8 Plasmodium falciparum erythrocyte membrane protein 1 is associated with cerebral malaria in Benin Sir2 paralogues cooperate to regulate virulence genes and antigenic variation in Plasmodium falciparum Population genomics of the immune evasion (var) genes of Plasmodium falciparum.Plasmodium falciparum transcriptome analysis reveals pregnancy malaria associated gene expression.Putative DNA G-quadruplex formation within the promoters of Plasmodium falciparum var genes.Plasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes--divide and conquer.Allelic diversity of the Plasmodium falciparum erythrocyte membrane protein 1 entails variant-specific red cell surface epitopes.Immunisation with recombinant PfEMP1 domains elicits functional rosette-inhibiting and phagocytosis-inducing antibodies to Plasmodium falciparum.The role of EPCR in the pathogenesis of severe malaria A molecular epidemiological study of var gene diversity to characterize the reservoir of Plasmodium falciparum in humans in Africa Specific receptor usage in Plasmodium falciparum cytoadherence is associated with disease outcome.Cloning of the repertoire of individual Plasmodium falciparum var genes using transformation associated recombination (TAR)Adhesion of Plasmodium falciparum-infected erythrocytes to human cells: molecular mechanisms and therapeutic implications.Investigating the host binding signature on the Plasmodium falciparum PfEMP1 protein family.Amplification of P. falciparum Cytoadherence through induction of a pro-adhesive state in host endothelium.Cytoadherence phenotype of Plasmodium falciparum-infected erythrocytes is associated with specific pfemp-1 expression in parasites from children with cerebral malaria Strain variation in early innate cytokine induction by Plasmodium falciparum.A plasma survey using 38 PfEMP1 domains reveals frequent recognition of the Plasmodium falciparum antigen VAR2CSA among young Tanzanian children.Surface antigens of Plasmodium falciparum-infected erythrocytes as immune targets and malaria vaccine candidates.Erasing the epigenetic memory and beginning to switch--the onset of antigenic switching of var genes in Plasmodium falciparum The humoral response to Plasmodium falciparum VarO rosetting variant and its association with protection against malaria in Beninese children.Evolution of the multi-domain structures of virulence genes in the human malaria parasite, Plasmodium falciparum.Induction of strain-transcending antibodies against Group A PfEMP1 surface antigens from virulent malaria parasites.Plasmodium falciparum erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in children.A restricted subset of var genes mediates adherence of Plasmodium falciparum-infected erythrocytes to brain endothelial cells.A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells A novel domain cassette identifies Plasmodium falciparum PfEMP1 proteins binding ICAM-1 and is a target of cross-reactive, adhesion-inhibitory antibodies.DC8 and DC13 var genes associated with severe malaria bind avidly to diverse endothelial cells.The var3 genes of Plasmodium falciparum 3D7 strain are differentially expressed in infected erythrocytes.Plasmodium falciparum var genes expressed in children with severe malaria encode CIDRα1 domains.The Severity of Plasmodium falciparum Infection Is Associated with Transcript Levels of var Genes Encoding Endothelial Protein C Receptor-Binding P. falciparum Erythrocyte Membrane Protein 1.Differential PfEMP1 expression is associated with cerebral malaria pathology.

P2860

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P2860

Differential var gene transcription in Plasmodium falciparum isolates from patients with cerebral malaria compared to hyperparasitaemia

http://www.wikidata.org/entity/Q34568283

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2006 nî lūn-bûn

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2006年論文

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Differential var gene transcri ...... compared to hyperparasitaemia

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Differential var gene transcri ...... compared to hyperparasitaemia

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Differential var gene transcri ...... compared to hyperparasitaemia

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Differential var gene transcri ...... compared to hyperparasitaemia

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Differential var gene transcri ...... compared to hyperparasitaemia

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Differential var gene transcri ...... compared to hyperparasitaemia

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Differential var gene transcri ...... compared to hyperparasitaemia

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J.MOLBIOPARA.2006.08.005

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Molecular and Biochemical Parasitology

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Differential var gene transcri ...... compared to hyperparasitaemia

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Abdoulaye K Koné

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Ahmed Raza

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Helen M Kyriacou

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J Alexandra Rowe

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Kirsten E Lyke

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Richard J Challis

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P2860

Genome sequence of the human malaria parasite Plasmodium falciparum

Antigenic variation in malaria: in situ switching, relaxed and mutually exclusive transcription of var genes during intra-erythrocytic development in Plasmodium falciparum

MUSCLE: multiple sequence alignment with high accuracy and high throughput

Sub-grouping of Plasmodium falciparum 3D7 var genes based on sequence analysis of coding and non-coding regions

Plasmodium falciparum variant surface antigen expression patterns during malaria

Heritability of malaria in Africa

P. falciparum rosetting mediated by a parasite-variant erythrocyte membrane protein and complement-receptor 1

Application of phylogenetic networks in evolutionary studies

The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of plasmodium falciparum-infected erythrocytes

Neighbor-net: an agglomerative method for the construction of phylogenetic networks

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211-218

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10.1016/J.MOLBIOPARA.2006.08.005

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2

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150

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Graham N. Stone

Christopher V Plowe

Mahamadou A. Thera

Ogobara K Doumbo

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2006-09-05T00:00:00Z

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6798696

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16996149

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cerebral malaria

Plasmodium falciparum

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2176080

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