Aberrant corepressor interactions implicated in PML-RAR(alpha) and PLZF-RAR(alpha) leukemogenesis reflect an altered recruitment and release of specific NCoR and SMRT splice variants.
about
Novel human BTB/POZ domain-containing zinc finger protein ZBTB1 inhibits transcriptional activities of CRENuclear receptor corepressor complexes in cancer: mechanism, function and regulationAlternative mRNA splicing of corepressors generates variants that play opposing roles in adipocyte differentiation.SMRTε, a corepressor variant, interacts with a restricted subset of nuclear receptors, including the retinoic acid receptors α and βLG-362B targets PML-RARα and blocks ATRA resistance of acute promyelocytic leukemia.Corepressor diversification by alternative mRNA splicing is species specific.Autoregulatory loop of nuclear corepressor 1 expression controls invasion, tumor growth, and metastasis8-CPT-cAMP/all-trans retinoic acid targets t(11;17) acute promyelocytic leukemia through enhanced cell differentiation and PLZF/RARα degradation.Ubiquitin specific protease 19 involved in transcriptional repression of retinoic acid receptor by stabilizing CORO2A.Antagonizing Retinoic Acid Receptors Increases Myeloid Cell Production by Cultured Human Hematopoietic Stem Cells.The ability of thyroid hormone receptors to sense t4 as an agonist depends on receptor isoform and on cellular cofactors.Short linear motif acquisition, exon formation and alternative splicing determine a pathway to diversity for NCoR-family co-repressors.Regulation of corepressor alternative mRNA splicing by hormonal and metabolic signaling.
P2860
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P2860
Aberrant corepressor interactions implicated in PML-RAR(alpha) and PLZF-RAR(alpha) leukemogenesis reflect an altered recruitment and release of specific NCoR and SMRT splice variants.
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Aberrant corepressor interactions implicated in PML-RAR
@nl
Aberrant corepressor interacti ...... NCoR and SMRT splice variants.
@ast
Aberrant corepressor interacti ...... NCoR and SMRT splice variants.
@en
type
label
Aberrant corepressor interactions implicated in PML-RAR
@nl
Aberrant corepressor interacti ...... NCoR and SMRT splice variants.
@ast
Aberrant corepressor interacti ...... NCoR and SMRT splice variants.
@en
prefLabel
Aberrant corepressor interactions implicated in PML-RAR
@nl
Aberrant corepressor interacti ...... NCoR and SMRT splice variants.
@ast
Aberrant corepressor interacti ...... NCoR and SMRT splice variants.
@en
P2093
P2860
P356
P1476
Aberrant corepressor interacti ...... NCoR and SMRT splice variants
@en
P2093
Brenda J Mengeling
Martin L Privalsky
Theresa Q Phan
P2860
P304
P356
10.1074/JBC.M110.200964
P407
P577
2010-12-03T00:00:00Z