Discovery of S-(2-guanidylethyl)-isothiourea (VUF 8430) as a potent nonimidazole histamine H4 receptor agonist.
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Antagonist affinity measurements at the Gi-coupled human histamine H3 receptor expressed in CHO cellsInternational Union of Basic and Clinical Pharmacology. XCVIII. Histamine ReceptorsLuciferase reporter gene assay on human, murine and rat histamine H4 receptor orthologs: correlations and discrepancies between distal and proximal readoutsSequential application of ligand and structure based modeling approaches to index chemicals for their hH4R antagonismThe Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsThe extracellular loop 2 (ECL2) of the human histamine H4 receptor substantially contributes to ligand binding and constitutive activity.Postsynaptic mechanisms underlying the excitatory action of histamine on medial vestibular nucleus neurons in rats.Molecular and cellular analysis of human histamine receptor subtypes.Molecular and biochemical pharmacology of the histamine H4 receptor.Histamine H4 receptor ligands and their potential therapeutic applications.Biological activities of guanidine compounds.Histamine H4 receptor ligands and their potential therapeutic applications: an update.Biological activities of guanidine compounds, 2008 - 2012 update.Histamine H4 receptor ligands: future applications and state of art.Profiling of histamine H4 receptor agonists in native human monocytes.Development of a profiling strategy for metabolic mixtures by combining chromatography and mass spectrometry with cell-based GPCR signaling.Pharmacological characterization of the new histamine H4 receptor agonist VUF 8430.Synthesis and histamine H(3) and H(4) receptor activity of conformationally restricted cyanoguanidines related to UR-PI376.Molecular determinants for the high constitutive activity of the human histamine H4 receptor: functional studies on orthologues and mutants.Effects of histamine H4 receptor ligands in a mouse model of gastric ulceration.Carbon-11 radiolabelling of organosulfur compounds: (11) C synthesis of the progesterone receptor agonist tanaproget.Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity.Mapping histamine H4receptor–ligand binding modes
P2860
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P2860
Discovery of S-(2-guanidylethyl)-isothiourea (VUF 8430) as a potent nonimidazole histamine H4 receptor agonist.
description
2006 nî lūn-bûn
@nan
2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Discovery of S-
@nl
Discovery of S-(2-guanidylethy ...... histamine H4 receptor agonist.
@ast
Discovery of S-(2-guanidylethy ...... histamine H4 receptor agonist.
@en
type
label
Discovery of S-
@nl
Discovery of S-(2-guanidylethy ...... histamine H4 receptor agonist.
@ast
Discovery of S-(2-guanidylethy ...... histamine H4 receptor agonist.
@en
prefLabel
Discovery of S-
@nl
Discovery of S-(2-guanidylethy ...... histamine H4 receptor agonist.
@ast
Discovery of S-(2-guanidylethy ...... histamine H4 receptor agonist.
@en
P2093
P356
P1476
Discovery of S-(2-guanidylethy ...... histamine H4 receptor agonist.
@en
P2093
Cindy M E van Dam
Herman D Lim
Iwan J P de Esch
Remko A Bakker
Rogier A Smits
P304
P356
10.1021/JM060880D
P407
P577
2006-11-01T00:00:00Z