Interstrain differences in the liver effects of trichloroethylene in a multistrain panel of inbred mice
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A mouse diversity panel approach reveals the potential for clinical kidney injury due to DB289 not predicted by classical rodent modelsHepatocellular carcinoma and the risk of occupational exposureEpigenetic mechanisms of mouse interstrain variability in genotoxicity of the environmental toxicant 1,3-butadieneTarget Organ Metabolism, Toxicity, and Mechanisms of Trichloroethylene and Perchloroethylene: Key Similarities, Differences, and Data GapsAddressing human variability in next-generation human health risk assessments of environmental chemicalsThe trichloroethylene metabolite S-(1,2-dichlorovinyl)-l-cysteine but not trichloroacetate inhibits pathogen-stimulated TNF-α in human extraplacental membranes in vitroSusceptibility to quantum dot induced lung inflammation differs widely among the Collaborative Cross founder mouse strainsPhysiologically based pharmacokinetic (PBPK) modeling of interstrain variability in trichloroethylene metabolism in the mouse.Trichloroethylene biotransformation and its role in mutagenicity, carcinogenicity and target organ toxicity.Toxicogenomic analysis reveals profibrogenic effects of trichloroethylene in autoimmune-mediated cholangitis in miceTrichloroethylene-induced gene expression and DNA methylation changes in B6C3F1 mouse liverComparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: liver effects.Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: kidney effects.Mouse Phenome Database (MPD)Trichloroethylene: Mechanistic, epidemiologic and other supporting evidence of carcinogenic hazard.Advancing toxicology research using in vivo high throughput toxicology with small fish models.Non‑infective occupational risk factors for hepatocellular carcinoma: A review (Review).Characterization of Variability in Toxicokinetics and Toxicodynamics of Tetrachloroethylene Using the Collaborative Cross Mouse Population.Editor's Highlight: Collaborative Cross Mouse Population Enables Refinements to Characterization of the Variability in Toxicokinetics of Trichloroethylene and Provides Genetic Evidence for the Role of PPAR Pathway in Its Oxidative Metabolism.Advancing chemical risk assessment decision-making with population variability data: challenges and opportunities.Characterization of inter-tissue and inter-strain variability of TCE glutathione conjugation metabolites DCVG, DCVC, and NAcDCVC in the mouse.Incorporating population-level genetic variability within laboratory models in toxicology: From the individual to the population.Corn oil as a vehicle in drug development exerts a dose-dependent effect on gene expression profiles in rat thymus.New Rodent Population Models May Inform Human Health Risk Assessment and Identification of Genetic Susceptibility to Environmental Exposures.Population-based dose-response analysis of liver transcriptional response to trichloroethylene in mouse.Tissue- and strain-specific effects of a genotoxic carcinogen 1,3-butadiene on chromatin and transcription.Regulatory forum opinion piece: Tox21 and toxicologic pathology.Genetic and epigenetic determinants of inter-individual variability in responses to toxicantsIncorporation of the glutathione conjugation pathway in an updated physiologically-based pharmacokinetic model for perchloroethylene in mice
P2860
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P2860
Interstrain differences in the liver effects of trichloroethylene in a multistrain panel of inbred mice
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2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Interstrain differences in the ...... ltistrain panel of inbred mice
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Interstrain differences in the ...... ltistrain panel of inbred mice
@en
Interstrain differences in the ...... ltistrain panel of inbred mice
@nl
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Interstrain differences in the ...... ltistrain panel of inbred mice
@ast
Interstrain differences in the ...... ltistrain panel of inbred mice
@en
Interstrain differences in the ...... ltistrain panel of inbred mice
@nl
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Interstrain differences in the ...... ltistrain panel of inbred mice
@ast
Interstrain differences in the ...... ltistrain panel of inbred mice
@en
Interstrain differences in the ...... ltistrain panel of inbred mice
@nl
P2093
P2860
P50
P356
P1476
Interstrain differences in the ...... ltistrain panel of inbred mice
@en
P2093
Blair U Bradford
David Harbourt
Dennis R Koop
Eric F Lock
Igor P Pogribny
Ivan Rusyn
Lisa Bleyle
Michelle DeSimone
Oksana Kosyk
Takeki Uehara
P2860
P304
P356
10.1093/TOXSCI/KFQ362
P577
2010-12-06T00:00:00Z