Human prx1 gene is a target of Nrf2 and is up-regulated by hypoxia/reoxygenation: implication to tumor biology.
about
Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancyHydrogen peroxide - production, fate and role in redox signaling of tumor cellsThe sulfiredoxin-peroxiredoxin (Srx-Prx) axis in cell signal transduction and cancer developmentNrf2 protein up-regulates antiapoptotic protein Bcl-2 and prevents cellular apoptosisRegulation of Nrf2-an updateAnti-apoptotic proteins and catalase-dependent apoptosis resistance in nickel chloride-transformed human lung epithelial cellsThioredoxins, glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: from cofactors to antioxidants to redox signalingA novel mechanism for cytoprotection against hypoxic injury: δ-opioid receptor-mediated increase in Nrf2 translocationNrf2 and NF-κB and Their Concerted Modulation in Cancer Pathogenesis and ProgressionRegulation of signal transduction by reactive oxygen species in the cardiovascular systemThe transcription factor NF-E2-related factor 2 (Nrf2): a protooncogene?Nrf2 signaling and cell survivalMechanism of chemical activation of Nrf2Nrf2:INrf2 (Keap1) signaling in oxidative stressOxidative stress, inflammation, and cancer: how are they linked?Genetic deletion of Nrf2 promotes immortalization and decreases life span of murine embryonic fibroblasts.T-cell activation under hypoxic conditions enhances IFN-gamma secretion.Nrf2-dependent sulfiredoxin-1 expression protects against cigarette smoke-induced oxidative stress in lungs.Nitrosative stress induces peroxiredoxin 1 ubiquitination during ischemic insult via E6AP activation in endothelial cells both in vitro and in vivo.Embryotoxicity Caused by DON-Induced Oxidative Stress Mediated by Nrf2/HO-1 Pathway.NRF2 activation restores disease related metabolic deficiencies in olfactory neurosphere-derived cells from patients with sporadic Parkinson's diseaseAn autoregulatory loop between Nrf2 and Cul3-Rbx1 controls their cellular abundanceGlobal gene expression profiling in three tumor cell lines subjected to experimental cycling and chronic hypoxia.Redox control systems in the nucleus: mechanisms and functions.Expression of ABCG2 (BCRP) is regulated by Nrf2 in cancer cells that confers side population and chemoresistance phenotype.Peroxiredoxin 1 stimulates secretion of proinflammatory cytokines by binding to TLR4Ionizing radiation activates the Nrf2 antioxidant response.Peroxiredoxin 1 stimulates endothelial cell expression of VEGF via TLR4 dependent activation of HIF-1α.Stepping up melanocytes to the challenge of UV exposure.RNAi-mediated silencing of nuclear factor erythroid-2-related factor 2 gene expression in non-small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapy.Clinical significance of Keap1 and Nrf2 in oral squamous cell carcinoma.Induction of peroxiredoxin 1 by hypoxia regulates heme oxygenase-1 via NF-κB in oral cancer.Expression of the progenitor marker NG2/CSPG4 predicts poor survival and resistance to ionising radiation in glioblastoma.The redox-sensitive transcription factor Nrf2 regulates murine hematopoietic stem cell survival independently of ROS levels.Adenovirus-Mediated Over-Expression of Nrf2 Within Mesenchymal Stem Cells (MSCs) Protected Rats Against Acute Kidney Injury.Dithiol-based compounds maintain expression of antioxidant protein peroxiredoxin 1 that counteracts toxicity of mutant huntingtin.Aberrant expression of peroxiredoxin 1 and its clinical implications in liver cancer.Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alpha.Oxidative stress response and Nrf2 signaling in aging.Cervical Cancer Cell Line Secretome Highlights the Roles of Transforming Growth Factor-Beta-Induced Protein ig-h3, Peroxiredoxin-2, and NRF2 on Cervical Carcinogenesis.
P2860
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P2860
Human prx1 gene is a target of Nrf2 and is up-regulated by hypoxia/reoxygenation: implication to tumor biology.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Human prx1 gene is a target of ...... implication to tumor biology.
@ast
Human prx1 gene is a target of ...... implication to tumor biology.
@en
Human prx1 gene is a target of ...... implication to tumor biology.
@nl
type
label
Human prx1 gene is a target of ...... implication to tumor biology.
@ast
Human prx1 gene is a target of ...... implication to tumor biology.
@en
Human prx1 gene is a target of ...... implication to tumor biology.
@nl
prefLabel
Human prx1 gene is a target of ...... implication to tumor biology.
@ast
Human prx1 gene is a target of ...... implication to tumor biology.
@en
Human prx1 gene is a target of ...... implication to tumor biology.
@nl
P2093
P1433
P1476
Human prx1 gene is a target of ...... implication to tumor biology.
@en
P2093
Clement Ip
Ji-Yeon Ahn
Ping Liang
Young-Mee Park
Yuesheng Zhang
Yun-Jeong Kim
P304
P356
10.1158/0008-5472.CAN-06-2401
P407
P577
2007-01-01T00:00:00Z