Pituitary adenylate cyclase-activating polypeptide (PACAP) decreases ischemic neuronal cell death in association with IL-6.
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PACAP suppresses dry eye signs by stimulating tear secretion.PACAP deficiency sensitizes nigrostriatal dopaminergic neurons to paraquat-induced damage and modulates central and peripheral inflammatory activation in miceIncreased behavioral and neuronal responses to a hallucinogenic drug in PACAP heterozygous mutant mice.RANTES release contributes to the protective action of PACAP38 against sodium nitroprusside in cortical neuronsMeta-analysis of microarray-derived data from PACAP-deficient adrenal gland in vivo and PACAP-treated chromaffin cells identifies distinct classes of PACAP-regulated genes.Altered anti-inflammatory response of mononuclear cells to neuropeptide PACAP is associated with deregulation of NF-{kappa}B in chronic pancreatitis.Interferon-gamma produced by microglia and the neuropeptide PACAP have opposite effects on the viability of neural progenitor cells.Pituitary adenylate cyclase-activating polypeptide (PACAP)/PAC1HOP1 receptor activation coordinates multiple neurotrophic signaling pathways: Akt activation through phosphatidylinositol 3-kinase gamma and vesicle endocytosis for neuronal survivalDiscovery of pituitary adenylate cyclase-activating polypeptide-regulated genes through microarray analyses in cell culture and in vivo.Neuroprotective roles of pituitary adenylate cyclase-activating polypeptide in neurodegenerative diseases.A cAMP-dependent, protein kinase A-independent signaling pathway mediating neuritogenesis through Egr1 in PC12 cells.PACAP38 differentially effects genes and CRMP2 protein expression in ischemic core and penumbra regions of permanent middle cerebral artery occlusion model mice brain.Pituitary adenylate cyclase activating polypeptide (PACAP) dilates cerebellar arteries through activation of large-conductance Ca(2+)-activated (BK) and ATP-sensitive (K ATP) K (+) channels.Transcriptomics and proteomics analyses of the PACAP38 influenced ischemic brain in permanent middle cerebral artery occlusion model mice.VIP and PACAP: recent insights into their functions/roles in physiology and disease from molecular and genetic studies.PACAP, an autocrine/paracrine regulator of gonadotrophsPACAP modulation of calcium ion activity in developing granule cells of the neonatal mouse olfactory bulb.Comparative protein composition of the brains of PACAP-deficient mice using mass spectrometry-based proteomic analysis.Human mesenchymal stem/stromal cells suppress spinal inflammation in mice with contribution of pituitary adenylate cyclase-activating polypeptide (PACAP).PAC1hop, null and hip receptors mediate differential signaling through cyclic AMP and calcium leading to splice variant-specific gene induction in neural cellsTargeting VIP and PACAP receptor signalling: new therapeutic strategies in multiple sclerosis.PACAP enhances axon outgrowth in cultured hippocampal neurons to a comparable extent as BDNF.STC1 induction by PACAP is mediated through cAMP and ERK1/2 but not PKA in cultured cortical neuronsUnraveling the ischemic brain transcriptome in a permanent middle cerebral artery occlusion mouse model by DNA microarray analysis.Signaling through the neuropeptide GPCR PAC₁ induces neuritogenesis via a single linear cAMP- and ERK-dependent pathway using a novel cAMP sensor.Pharmacology and functions of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide: IUPHAR review 1.A novel hydrogen sulfide-releasing N-methyl-D-aspartate receptor antagonist prevents ischemic neuronal deathConvergent phosphomodulation of the major neuronal dendritic potassium channel Kv4.2 by pituitary adenylate cyclase-activating polypeptide.Ras family small GTPase-mediated neuroprotective signaling in stroke.Impaired nerve regeneration and enhanced neuroinflammatory response in mice lacking pituitary adenylyl cyclase activating peptide.Thiosulfate Mediates Cytoprotective Effects of Hydrogen Sulfide Against Neuronal Ischemia.VIP and PACAP: neuropeptide modulators of CNS inflammation, injury, and repairPACAP38 increases vesicular monoamine transporter 2 (VMAT2) expression and attenuates methamphetamine toxicity.Therapeutic antibodies that target inflammatory cytokines in autoimmune diseasesLong-Term Estrogen Receptor Beta Agonist Treatment Modifies the Hippocampal Transcriptome in Middle-Aged Ovariectomized Rats.Unraveling the Specific Ischemic Core and Penumbra Transcriptome in the Permanent Middle Cerebral Artery Occlusion Mouse Model Brain Treated with the Neuropeptide PACAP38.PACAP signaling exerts opposing effects on neuroprotection and neuroinflammation during disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosisPACAP: a master regulator of neuroendocrine stress circuits and the cellular stress responsePACAP is an endogenous protective factor-insights from PACAP-deficient mice.Distribution and protective function of pituitary adenylate cyclase-activating polypeptide in the retina.
P2860
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P2860
Pituitary adenylate cyclase-activating polypeptide (PACAP) decreases ischemic neuronal cell death in association with IL-6.
description
2006 nî lūn-bûn
@nan
2006 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Pituitary adenylate cyclase-ac ...... eath in association with IL-6.
@ast
Pituitary adenylate cyclase-ac ...... eath in association with IL-6.
@en
type
label
Pituitary adenylate cyclase-ac ...... eath in association with IL-6.
@ast
Pituitary adenylate cyclase-ac ...... eath in association with IL-6.
@en
prefLabel
Pituitary adenylate cyclase-ac ...... eath in association with IL-6.
@ast
Pituitary adenylate cyclase-ac ...... eath in association with IL-6.
@en
P2093
P2860
P50
P356
P1476
Pituitary adenylate cyclase-ac ...... eath in association with IL-6.
@en
P2093
Akemichi Baba
Akira Arimura
Atsushi Takaki
Hirokazu Ohtaki
Kei Hodoyama
Kouhei Matsuda
Sachiko Yofu
Seiji Shioda
Tomoya Nakamachi
Yoichi Aizawa
P2860
P304
P356
10.1073/PNAS.0600375103
P407
P577
2006-05-01T00:00:00Z