about
Hypoxia-inducible C-to-U coding RNA editing downregulates SDHB in monocytesCoding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAsThe non-genomic loss of function of tumor suppressors: an essential role in the pathogenesis of chronic myeloid leukemia chronic phaseEtiologic field effect: reappraisal of the field effect concept in cancer predisposition and progressionHow many molecular subtypes? Implications of the unique tumor principle in personalized medicinePTEN plasticity: how the taming of a lethal gene can go too farEpigenetics of lung cancerDiscovery of colorectal cancer PIK3CA mutation as potential predictive biomarker: power and promise of molecular pathological epidemiologyCompeting endogenous RNAs (ceRNAs): new entrants to the intricacies of gene regulationPrediction of response to anti-EGFR antibody-based therapies by multigene sequencing in colorectal cancer patients.Mourning Dr. Alfred G. Knudson: the two-hit hypothesis, tumor suppressor genes, and the tuberous sclerosis complexIdentifying High-Risk Chronic Lymphocytic Leukemia: A Pathogenesis-Oriented Appraisal of Prognostic and Predictive Factors in Patients Treated with Chemotherapy with or without ImmunotherapyThe genetic heterogeneity of colorectal cancer predisposition - guidelines for gene discoveryMolecular Aspects of Head and Neck Cancer TherapyThe intrinsically disordered tails of PTEN and PTEN-L have distinct roles in regulating substrate specificity and membrane activityARID1A mutations in cancer: another epigenetic tumor suppressor?BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal CancerOncogenic RAS directs silencing of tumor suppressor genes through ordered recruitment of transcriptional repressorsGenome-wide mutation avalanches induced in diploid yeast cells by a base analog or an APOBEC deaminaseInvestigation of the atypical FBXW7 mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestinesFunctional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells.Models of signalling networks - what cell biologists can gain from them and give to themGenome-wide haploinsufficiency screen reveals a novel role for γ-TuSC in spindle organization and genome stability.DEAR1 is a chromosome 1p35 tumor suppressor and master regulator of TGF-β-driven epithelial-mesenchymal transitionRealizing the promise of cancer predisposition genes.MicroRNA-155-5p promotes hepatocellular carcinoma progression by suppressing PTEN through the PI3K/Akt pathway.Recurrent hemizygous deletions in cancers may optimize proliferative potentialGenomics of squamous cell lung cancerA strategy to identify dominant point mutant modifiers of a quantitative trait.PTEN mutations as a cause of constitutive insulin sensitivity and obesity.Haploinsufficient tumor suppressor genes.Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse modelThe onset of p53 loss of heterozygosity is differentially induced in various stem cell types and may involve the loss of either alleleThe docking protein p130Cas regulates cell sensitivity to proteasome inhibition.Two single nucleotide polymorphisms in the von Hippel-Lindau tumor suppressor gene in Taiwanese with renal cell carcinoma.BRCA1 mRNA levels following a 4-6-week intervention with oral 3,3'-diindolylmethaneVGLL3 expression is associated with a tumor suppressor phenotype in epithelial ovarian cancerGenetically engineered mouse models of PI3K signaling in breast cancer.The oncogenic microRNA miR-22 targets the TET2 tumor suppressor to promote hematopoietic stem cell self-renewal and transformation.Overview of the biochemical and genetic processes in malignant mesothelioma.
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A continuum model for tumour suppression.
@ast
A continuum model for tumour suppression.
@en
A continuum model for tumour suppression.
@nl
type
label
A continuum model for tumour suppression.
@ast
A continuum model for tumour suppression.
@en
A continuum model for tumour suppression.
@nl
prefLabel
A continuum model for tumour suppression.
@ast
A continuum model for tumour suppression.
@en
A continuum model for tumour suppression.
@nl
P2860
P356
P1433
P1476
A continuum model for tumour suppression.
@en
P2093
Alfred G Knudson
Alice H Berger
P2860
P2888
P304
P356
10.1038/NATURE10275
P407
P577
2011-08-10T00:00:00Z
P5875
P6179
1035638856