Targeting α4β7 integrin reduces mucosal transmission of simian immunodeficiency virus and protects gut-associated lymphoid tissue from infection.
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Reversing Gut Damage in HIV Infection: Using Non-Human Primate Models to Instruct Clinical ResearchA Small Molecule, Which Competes with MAdCAM-1, Activates Integrin α4β7 and Fails to Prevent Mucosal Transmission of SHIV-SF162P3PolyICLC Exerts Pro- and Anti-HIV Effects on the DC-T Cell Milieu In Vitro and In VivoBottlenecks in HIV-1 transmission: insights from the study of founder virusesThe V1V2 Region of HIV-1 gp120 Forms a Five-Stranded Beta Barrel.Effectiveness of UNAIDS targets and HIV vaccination across 127 countries.Characteristics of HIV target CD4 T cells collected using different sampling methods from the genital tract of HIV seronegative womenPentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge.Retinoic acid imprints a mucosal-like phenotype on dendritic cells with an increased ability to fuel HIV-1 infection.South African HIV-1 subtype C transmitted variants with a specific V2 motif show higher dependence on α4β7 for replication.Macaque models of enhanced susceptibility to HIV.Phenotypic and Functional Characterization of Monoclonal Antibodies with Specificity for Rhesus Macaque CD200, CD200R and MincleIdentification of New Regions in HIV-1 gp120 Variable 2 and 3 Loops that Bind to α4β7 Integrin Receptor.Human Blood-Circulating Basophils Capture HIV-1 and Mediate Viral trans-Infection of CD4+ T Cells.Comparable Antigenicity and Immunogenicity of Oligomeric Forms of a Novel, Acute HIV-1 Subtype C gp145 Envelope for Use in Preclinical and Clinical Vaccine ResearchRelationship of menstrual cycle and vaginal infection in female rhesus macaques challenged with repeated, low doses of SIVmac251.HIV transmission biology: translation for HIV prevention.Differentiating founder and chronic HIV envelope sequences.Species-specific differences in the expression and regulation of α4β7 integrin in various nonhuman primatesSignatures in Simian Immunodeficiency Virus SIVsmE660 Envelope gp120 Are Associated with Mucosal Transmission but Not Vaccination Breakthrough in Rhesus MacaquesHuman Mucosal Mast Cells Capture HIV-1 and Mediate Viral trans-Infection of CD4+ T Cells.Differences in expression of gut-homing receptors on CD4+ T cells in black and white HIV-negative men who have sex with menProgesterone Levels Associate with a Novel Population of CCR5+CD38+ CD4 T Cells Resident in the Genital Mucosa with Lymphoid Trafficking Potential.Worldwide Genetic Features of HIV-1 Env α4β7 Binding Motif: The Local Dissemination Impact of the LDI Tripeptide.Initiation of antiretroviral therapy before detection of colonic infiltration by HIV reduces viral reservoirs, inflammation and immune activation.Pair housing of Macaques: A review of partner selection, introduction techniques, monitoring for compatibility, and methods for long-term maintenance of pairs.Antibodies to P-selectin glycoprotein ligand-1 block dendritic cell-mediated enterovirus 71 transmission and prevent virus-induced cells death.Ontogeny of CD4+ T Lymphocytes With Phenotypic Susceptibility to HIV-1 During Exclusive and Nonexclusive Breastfeeding in HIV-1-Exposed Ugandan Infants.Complex immune correlates of protection in HIV-1 vaccine efficacy trials.Virus-Host Gene Interactions Define HIV-1 Disease Progression.Extracellular Matrix Proteins Mediate HIV-1 gp120 Interactions with α4β7.Virion incorporation of integrin α4β7 facilitates HIV-1 infection and intestinal homing.Early initiation of antiretroviral treatment postSIV infection does not resolve lymphoid tissue activation.Acute Simian Immunodeficiency Virus Infection Triggers Early and Transient Interleukin-7 Production in the Gut, Leading to Enhanced Local Chemokine Expression and Intestinal Immune Cell Homing.Glycosylation and oligomeric state of envelope protein might influence HIV-1 virion capture by α4β7 integrin.Sustained virologic control in SIV+ macaques after antiretroviral and α4β7 antibody therapy.Brief Report: A High Rate of β7+ Gut-Homing Lymphocytes in HIV-Infected Immunological Nonresponders is Associated With Poor CD4 T-Cell Recovery During Suppressive HAARTThe Role of Integrin Expressing Cells in Modulating Disease Susceptibility and Progression (January 2016).The HIV-1 transmission bottleneck.Hormonal Contraception and HIV-1 Acquisition: Biological Mechanisms.
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Targeting α4β7 integrin reduces mucosal transmission of simian immunodeficiency virus and protects gut-associated lymphoid tissue from infection.
description
2014 nî lūn-bûn
@nan
2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Targeting α4β7 integrin reduce ...... ymphoid tissue from infection.
@ast
Targeting α4β7 integrin reduce ...... ymphoid tissue from infection.
@en
Targeting α4β7 integrin reduce ...... ymphoid tissue from infection.
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Targeting α4β7 integrin reduce ...... ymphoid tissue from infection.
@ast
Targeting α4β7 integrin reduce ...... ymphoid tissue from infection.
@en
Targeting α4β7 integrin reduce ...... ymphoid tissue from infection.
@nl
prefLabel
Targeting α4β7 integrin reduce ...... ymphoid tissue from infection.
@ast
Targeting α4β7 integrin reduce ...... ymphoid tissue from infection.
@en
Targeting α4β7 integrin reduce ...... ymphoid tissue from infection.
@nl
P2093
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P356
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Targeting α4β7 integrin reduce ...... ymphoid tissue from infection.
@en
P2093
Ann E Mayne
Brianne Kallam
Dawn Little
Debra Hanson
Ellen N Kersh
Fatima Nawaz
Francois Villinger
James Arthos
Janet M McNicholl
Keith A Reimann
P2860
P2888
P304
P356
10.1038/NM.3715
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P50
P577
2014-11-24T00:00:00Z
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P6179
1016825036