Dynamic in vivo interaction of DDB2 E3 ubiquitin ligase with UV-damaged DNA is independent of damage-recognition protein XPC.
about
Monoubiquitinated histone H2A destabilizes photolesion-containing nucleosomes with concomitant release of UV-damaged DNA-binding protein E3 ligaseStructural basis of UV DNA-damage recognition by the DDB1-DDB2 complexDynamic regulation of the COP9 signalosome in response to DNA damageDamaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repairDistinct and overlapping functions of the cullin E3 ligase scaffolding proteins CUL4A and CUL4BCSNAP Is a Stoichiometric Subunit of the COP9 SignalosomeNucleotide excision repair proteins rapidly accumulate but fail to persist in human XP-E (DDB2 mutant) cellsRegulation and role of Arabidopsis CUL4-DDB1A-DDB2 in maintaining genome integrity upon UV stressSignaling efficiency of Gαq through its effectors p63RhoGEF and GEFT depends on their subcellular locationSingle-molecule analysis reveals human UV-damaged DNA-binding protein (UV-DDB) dimerizes on DNA via multiple kinetic intermediates.A role for MeCP2 in switching gene activity via chromatin unfolding and HP1γ displacement.Repair of laser-localized DNA interstrand cross-links in G1 phase mammalian cellsDDB2 complex-mediated ubiquitylation around DNA damage is oppositely regulated by XPC and Ku and contributes to the recruitment of XPA.Chromatin retention of DNA damage sensors DDB2 and XPC through loss of p97 segregase causes genotoxicity.Stochastic and reversible assembly of a multiprotein DNA repair complex ensures accurate target site recognition and efficient repair.Regulation of nucleotide excision repair by UV-DDB: prioritization of damage recognition to internucleosomal DNANER initiation factors, DDB2 and XPC, regulate UV radiation response by recruiting ATR and ATM kinases to DNA damage sitesPARP1 promotes nucleotide excision repair through DDB2 stabilization and recruitment of ALC1Damaged DNA-binding protein down-regulates epigenetic mark H3K56Ac through histone deacetylase 1 and 2.Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response.The NR4A2 nuclear receptor is recruited to novel nuclear foci in response to UV irradiation and participates in nucleotide excision repairLow-dose formaldehyde delays DNA damage recognition and DNA excision repair in human cells.Kinetic gating mechanism of DNA damage recognition by Rad4/XPCOrchestral maneuvers at the damaged sites in nucleotide excision repair.DDB2 promotes chromatin decondensation at UV-induced DNA damage.Molecular mechanisms of xeroderma pigmentosum (XP) proteins.Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition.Role of poly(ADP-ribose) polymerase-1 in the removal of UV-induced DNA lesions by nucleotide excision repair.Eukaryotic nucleotide excision repair: from understanding mechanisms to influencing biology.Heterochromatin protein 1 is recruited to various types of DNA damage.ZRF1 mediates remodeling of E3 ligases at DNA lesion sites during nucleotide excision repair.Assembly of multiprotein complexes that control genome function.DNA damage response.Detecting UV-lesions in the genome: The modular CRL4 ubiquitin ligase does it best!Abiotic stress tolerance mediated by protein ubiquitination.Post-translational modifications of lysine in DNA-damage repair.Monitoring repair of UV-induced 6-4-photoproducts with a purified DDB2 protein complex.Spatiotemporal regulation of posttranslational modifications in the DNA damage response.Decision for cell fate: deubiquitinating enzymes in cell cycle checkpoint.ATR- and ATM-Mediated DNA Damage Response Is Dependent on Excision Repair Assembly during G1 but Not in S Phase of Cell Cycle.
P2860
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P2860
Dynamic in vivo interaction of DDB2 E3 ubiquitin ligase with UV-damaged DNA is independent of damage-recognition protein XPC.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Dynamic in vivo interaction of ...... amage-recognition protein XPC.
@ast
Dynamic in vivo interaction of ...... amage-recognition protein XPC.
@en
Dynamic in vivo interaction of ...... amage-recognition protein XPC.
@nl
type
label
Dynamic in vivo interaction of ...... amage-recognition protein XPC.
@ast
Dynamic in vivo interaction of ...... amage-recognition protein XPC.
@en
Dynamic in vivo interaction of ...... amage-recognition protein XPC.
@nl
prefLabel
Dynamic in vivo interaction of ...... amage-recognition protein XPC.
@ast
Dynamic in vivo interaction of ...... amage-recognition protein XPC.
@en
Dynamic in vivo interaction of ...... amage-recognition protein XPC.
@nl
P2093
P356
P1476
Dynamic in vivo interaction of ...... damage-recognition protein XPC
@en
P2093
Adriaan B Houtsmuller
Bart Geverts
Hanneke Kool
Leon H F Mullenders
Martijn S Luijsterburg
Roel van Driel
Wim Vermeulen
P304
P356
10.1242/JCS.008367
P407
P577
2007-07-17T00:00:00Z