Response normalized liquid chromatography nanospray ionization mass spectrometry.
about
Selection of the optimum electrospray voltage for gradient elution LC-MS measurementsIdentification of drug metabolites in human plasma or serum integrating metabolite prediction, LC-HRMS and untargeted data processing.Integrated quantitative and qualitative workflow for in vivo bioanalytical support in drug discovery using hybrid Q-TOF-MS.Technologies and strategies to characterize and quantitate metabolites in drug discovery and development.Small molecule quantification by liquid chromatography-mass spectrometry for metabolites of drugs and drug candidates.NanoHPLC-nanoESI(+)-MS/MS quantitation of bis-N7-guanine DNA-DNA cross-links in tissues of B6C3F1 mice exposed to subppm levels of 1,3-butadiene.Improved intensity-based label-free quantification via proximity-based intensity normalization (PIN).Metabolite quantitation: detector technology and MIST implications.Novel MS solutions inspired by MIST.Addressing metabolite safety during first-in-man studies using ¹⁴C-labeled drug and accelerator mass spectrometry.Metabolite identification by mass spectrometry: forty years of evolution.Accelerator MS: its role as a frontline bioanalytical technique.Microfluidic chip-based liquid chromatography coupled to mass spectrometry for determination of small molecules in bioanalytical applications.Evaluation of relative LC/MS response of metabolites to parent drug in LC/nanospray ionization mass spectrometry: potential implications in MIST assessment.Evaluation of relative MS response factors of drug metabolites for semi-quantitative assessment of chemical liabilities in drug discovery.The advantages of microflow LC-MS/MS compared with conventional HPLC-MS/MS for the analysis of methotrexate from human plasma.Quantification of desloratadine in human plasma by LC-ESI-MS/MS and application to a pharmacokinetic study.Meeting the MIST regulations: human metabolism in Phase I using AMS and a tiered bioanalytical approach.
P2860
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P2860
Response normalized liquid chromatography nanospray ionization mass spectrometry.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Response normalized liquid chromatography nanospray ionization mass spectrometry.
@ast
Response normalized liquid chromatography nanospray ionization mass spectrometry.
@en
Response normalized liquid chromatography nanospray ionization mass spectrometry.
@nl
type
label
Response normalized liquid chromatography nanospray ionization mass spectrometry.
@ast
Response normalized liquid chromatography nanospray ionization mass spectrometry.
@en
Response normalized liquid chromatography nanospray ionization mass spectrometry.
@nl
prefLabel
Response normalized liquid chromatography nanospray ionization mass spectrometry.
@ast
Response normalized liquid chromatography nanospray ionization mass spectrometry.
@en
Response normalized liquid chromatography nanospray ionization mass spectrometry.
@nl
P2093
P2860
P1476
Response normalized liquid chromatography nanospray ionization mass spectrometry.
@en
P2093
Kevin B Alton
Neil Blumenkrantz
Ragu Ramanathan
Ruyun Zhong
Swapan K Chowdhury
P2860
P2888
P304
P356
10.1016/J.JASMS.2007.07.022
P577
2007-07-29T00:00:00Z
P5875
P6179
1042040352