Functional characterization of the TERRA transcriptome at damaged telomeres. - Test2 - elhamkhani - TriplyDB

Functional characterization of the TERRA transcriptome at damaged telomeres.

Functional characterization of the TERRA transcriptome at damaged telomeres.

http://www.wikidata.org/entity/Q34687678

about

Telomere and Telomerase Therapeutics in Cancer Spatiotemporal analysis with a genetically encoded fluorescent RNA probe reveals TERRA function around telomeres.The telomeric DNA damage response occurs in the absence of chromatin decompaction Heat shock factor 1 promotes TERRA transcription and telomere protection upon heat stress Neil2-null Mice Accumulate Oxidized DNA Bases in the Transcriptionally Active Sequences of the Genome and Are Susceptible to Innate Inflammation HULC cooperates with MALAT1 to aggravate liver cancer stem cells growth through telomere repeat-binding factor 2.Telomeric repeat-containing RNA (TERRA) constitutes a nucleoprotein component of extracellular inflammatory exosomes.Subtelomeric p53 binding prevents accumulation of DNA damage at human telomeres.Complex interactions between the DNA-damage response and mammalian telomeres.CUDR promotes liver cancer stem cell growth through upregulating TERT and C-Myc.SET1A Cooperates With CUDR to Promote Liver Cancer Growth and Hepatocyte-like Stem Cell Malignant Transformation Epigenetically.A two-state activation mechanism controls the histone methyltransferase Suv39h1.Telomeric RNAs are essential to maintain telomeres.TRF2-Mediated Control of Telomere DNA Topology as a Mechanism for Chromosome-End Protection E2F1-induced upregulation of long noncoding RNA LINC00668 predicts a poor prognosis of gastric cancer and promotes cell proliferation through epigenetically silencing of CKIs Transcription of telomeric DNA leads to high levels of homologous recombination and t-loops.Nuclear Noncoding RNAs and Genome Stability.Telomeres in ICF syndrome cells are vulnerable to DNA damage due to elevated DNA:RNA hybrids Double mutant P53 (N340Q/L344R) promotes hepatocarcinogenesis through upregulation of Pim1 mediated by PKM2 and LncRNA CUDR Telomeric repeat-containing RNA TERRA: a noncoding RNA connecting telomere biology to genome integrity Transcription of tandemly repetitive DNA: functional roles.Telomere homeostasis in mammalian germ cells: a review.Major satellite repeat RNA stabilize heterochromatin retention of Suv39h enzymes by RNA-nucleosome association and RNA:DNA hybrid formation.R-loop: an emerging regulator of chromatin dynamics.The long and the short of TRF2 in neurogenesis.RNA-mediated regulation of heterochromatin.G-quadruplex RNA binding and recognition by the lysine-specific histone demethylase-1 enzyme High-throughput single-molecule mapping links subtelomeric variants and long-range haplotypes with specific telomeres.Silencing repetitive DNA.RNA-dependent stabilization of SUV39H1 at constitutive heterochromatin.Impact of nucleic acid and methylated H3K9 binding activities of Suv39h1 on its heterochromatin assembly.The crosstalk of telomere dysfunction and inflammation through cell-free TERRA containing exosomes.Retrotransposon-derived p53 binding sites enhance telomere maintenance and genome protection.DNA damage response inhibition at dysfunctional telomeres by modulation of telomeric DNA damage response RNAs.CENP-A chromatin disassembly in stressed and senescent murine cells.Identification and characterization of a subtelomeric satellite DNA in Callitrichini monkeys.Long Noncoding RNAs in Mammalian Development and Diseases.CTCF driven TERRA transcription facilitates completion of telomere DNA replication.Structural Roles of Noncoding RNAs in the Heart of Enzymatic Complexes.Expression of Telomere-Associated Proteins is Interdependent to Stabilize Native Telomere Structure and Telomere Dysfunction by G-Quadruplex Ligand Causes TERRA Upregulation.

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Functional characterization of the TERRA transcriptome at damaged telomeres.

http://www.wikidata.org/entity/Q34687678

description

2014 nî lūn-bûn

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2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Functional characterization of the TERRA transcriptome at damaged telomeres.

@ast

Functional characterization of the TERRA transcriptome at damaged telomeres.

@en

Functional characterization of the TERRA transcriptome at damaged telomeres.

@nl

type

label

Functional characterization of the TERRA transcriptome at damaged telomeres.

@ast

Functional characterization of the TERRA transcriptome at damaged telomeres.

@en

Functional characterization of the TERRA transcriptome at damaged telomeres.

@nl

prefLabel

Functional characterization of the TERRA transcriptome at damaged telomeres.

@ast

Functional characterization of the TERRA transcriptome at damaged telomeres.

@en

Functional characterization of the TERRA transcriptome at damaged telomeres.

@nl

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Nature Communications

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Functional characterization of the TERRA transcriptome at damaged telomeres

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Harold Riethman

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Julien Delafontaine

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Sascha Feuerhahn

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P2860

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

Mapping and quantifying mammalian transcriptomes by RNA-Seq

Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay

The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells

The human RNA surveillance factor UPF1 is required for S phase progression and genome stability

A quantitative telomeric chromatin isolation protocol identifies different telomeric states

Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2

Human UPF1 interacts with TPP1 and telomerase and sustains telomere leading-strand replication

ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks

TIN2-tethered TPP1 recruits human telomerase to telomeres in vivo

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5

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Joachim Lingner

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4264578

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