WNK1 kinase isoform switch regulates renal potassium excretion. - Test2 - elhamkhani - TriplyDB

WNK1 kinase isoform switch regulates renal potassium excretion.

WNK1 kinase isoform switch regulates renal potassium excretion.

http://www.wikidata.org/entity/Q34694518

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The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex WNK3 positively regulates epithelial calcium channels TRPV5 and TRPV6 via a kinase-dependent pathway The thiazide-sensitive Na+-Cl- cotransporter: molecular biology, functional properties, and regulation by WNKs MicroRNA 802 stimulates ROMK channels by suppressing caveolin-1 Domains of WNK1 kinase in the regulation of ROMK1 Mutations in the nervous system--specific HSN2 exon of WNK1 cause hereditary sensory neuropathy type II Regulation of ROMK channel and K+ homeostasis by kidney-specific WNK1 kinase Intersectin links WNK kinases to endocytosis of ROMK1 A molecular update on pseudohypoaldosteronism type II Quantitative assessment of antibody internalization with novel monoclonal antibodies against Alexa fluorophores Identification of the WNK-SPAK/OSR1 signaling pathway in rodent and human lenses A SPAK isoform switch modulates renal salt transport and blood pressure LINGO-1 interacts with WNK1 to regulate nogo-induced inhibition of neurite extension WNK4 kinase stimulates caveola-mediated endocytosis of TRPV5 amplifying the dynamic range of regulation of the channel by protein kinase C Decreased ENaC expression compensates the increased NCC activity following inactivation of the kidney-specific isoform of WNK1 and prevents hypertension.MicroRNA-194 (miR-194) regulates ROMK channel activity by targeting intersectin 1.Lack of family-based association between common variations in WNK1 and blood pressure level WNK kinases and renal sodium transport in health and disease: an integrated view.The WNKs: atypical protein kinases with pleiotropic actions.Distal convoluted tubule WNK4-mediated regulation of renal ion transport proteins.Recent advances in distal tubular potassium handling Differential regulation of ROMK (Kir1.1) in distal nephron segments by dietary potassium Conservation of Na+ vs. K+ by the rat cortical collecting duct.WNK4 kinase inhibits Maxi K channel activity by a kinase-dependent mechanism.WNK1 activates large-conductance Ca2+-activated K+ channels through modulation of ERK1/2 signaling.Src-family protein tyrosine kinase phosphorylates WNK4 and modulates its inhibitory effect on KCNJ1 (ROMK).Alternatively spliced proline-rich cassettes link WNK1 to aldosterone action Protein phosphatase 1 modulates the inhibitory effect of With-no-Lysine kinase 4 on ROMK channels.Cell-specific regulation of L-WNK1 by dietary K.Interactions with WNK (with no lysine) family members regulate oxidative stress response 1 and ion co-transporter activity Regulation of transport in the connecting tubule and cortical collecting duct An unexpected journey: conceptual evolution of mechanoregulated potassium transport in the distal nephron.Multigene kinase network, kidney transport, and salt in essential hypertension.Effect of aldosterone on BK channel expression in mammalian cortical collecting duct.Heritable forms of hypertension.WNK1-related Familial Hyperkalemic Hypertension results from an increased expression of L-WNK1 specifically in the distal nephron.WNK4 diverts the thiazide-sensitive NaCl cotransporter to the lysosome and stimulates AP-3 interaction Regulation of potassium (K) handling in the renal collecting duct.Role of BKbeta1 in Na+ reabsorption by cortical collecting ducts of Na+-deprived mice

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P2860

WNK1 kinase isoform switch regulates renal potassium excretion.

http://www.wikidata.org/entity/Q34694518

description

2006 nî lūn-bûn

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2006 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2006 թվականի մայիսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

WNK1 kinase isoform switch regulates renal potassium excretion.

@ast

WNK1 kinase isoform switch regulates renal potassium excretion.

@en

WNK1 kinase isoform switch regulates renal potassium excretion.

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type

label

WNK1 kinase isoform switch regulates renal potassium excretion.

@ast

WNK1 kinase isoform switch regulates renal potassium excretion.

@en

WNK1 kinase isoform switch regulates renal potassium excretion.

@nl

prefLabel

WNK1 kinase isoform switch regulates renal potassium excretion.

@ast

WNK1 kinase isoform switch regulates renal potassium excretion.

@en

WNK1 kinase isoform switch regulates renal potassium excretion.

@nl

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PNAS.0603109103

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Proceedings of the National Academy of Sciences of the United States of America

P1476

WNK1 kinase isoform switch regulates renal potassium excretion

@en

P2093

Amanda Mason

http://www.w3.org/2001/XMLSchema#string

Arohan R Subramanya

http://www.w3.org/2001/XMLSchema#string

Chao-Ling Yang

http://www.w3.org/2001/XMLSchema#string

Dimin Li

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Djikolngar Maouyo

http://www.w3.org/2001/XMLSchema#string

James B Wade

http://www.w3.org/2001/XMLSchema#string

Jie Liu

http://www.w3.org/2001/XMLSchema#string

Liang Fang

http://www.w3.org/2001/XMLSchema#string

Paul A Welling

http://www.w3.org/2001/XMLSchema#string

P2860

WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis

WNK1 phosphorylates synaptotagmin 2 and modulates its membrane binding

Antagonistic regulation of ROMK by long and kidney-specific WNK1 isoforms.

Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4

Multiple promoters in the WNK1 gene: one controls expression of a kidney-specific kinase-defective isoform

Cell surface expression of the ROMK (Kir 1.1) channel is regulated by the aldosterone-induced kinase, SGK-1, and protein kinase A

Human hypertension caused by mutations in WNK kinases

Cloning and expression of an inwardly rectifying ATP-regulated potassium channel

WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion

Dominant-negative regulation of WNK1 by its kidney-specific kinase-defective isoform

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8558-8563

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10.1073/PNAS.0603109103

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22

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103

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David H. Ellison

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2006-05-18T00:00:00Z

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7071424

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16709664

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1482529

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