Structure-function relationships in the 2-oxo acid dehydrogenase family: substrate-specific signatures and functional predictions for the 2-oxoglutarate dehydrogenase-like proteins.
about
A nonsense mutation in DHTKD1 causes Charcot-Marie-Tooth disease type 2 in a large Chinese pedigreeThiamin diphosphate-dependent enzymes: from enzymology to metabolic regulation, drug design and disease modelsBCKDH: the missing link in apicomplexan mitochondrial metabolism is required for full virulence of Toxoplasma gondii and Plasmodium bergheiLoss of Nardilysin, a Mitochondrial Co-chaperone for α-Ketoglutarate Dehydrogenase, Promotes mTORC1 Activation and NeurodegenerationNovel isoenzyme of 2-oxoglutarate dehydrogenase is identified in brain, but not in heartDifferential gene expression profile of first-generation and second-generation rapamycin-resistant allogeneic T cellsDHTKD1 mutations cause 2-aminoadipic and 2-oxoadipic aciduria.DHTKD1 is essential for mitochondrial biogenesis and function maintenance.Genetic basis of alpha-aminoadipic and alpha-ketoadipic aciduria.OGDHL is a modifier of AKT-dependent signaling and NF-κB function.Molecular mechanisms of the non-coenzyme action of thiamin in brain: biochemical, structural and pathway analysis.Hydroxyproline metabolism in a mouse model of Primary Hyperoxaluria Type 3A survey of oxidative paracatalytic reactions catalyzed by enzymes that generate carbanionic intermediates: implications for ROS production, cancer etiology, and neurodegenerative diseases.Modulation of anti-cancer drug sensitivity through the regulation of mitochondrial activity by adenylate kinase 4.Biosynthesis of the salinosporamide A polyketide synthase substrate chloroethylmalonyl-coenzyme A from S-adenosyl-L-methionine.Inhibition of mitochondrial 2-oxoglutarate dehydrogenase impairs viability of cancer cells in a cell-specific metabolism-dependent manner.A novel role for fatty acid transport protein 1 in the regulation of tricarboxylic acid cycle and mitochondrial function in 3T3-L1 adipocytes.The logic of metabolism and its fuzzy consequences.The E2 domain of OdhA of Corynebacterium glutamicum has succinyltransferase activity dependent on lipoyl residues of the acetyltransferase AceFCalcium-insensitive splice variants of mammalian E1 subunit of 2-oxoglutarate dehydrogenase complex with tissue-specific patterns of expression.Studies on the regulation of the human E1 subunit of the 2-oxoglutarate dehydrogenase complex, including the identification of a novel calcium-binding site.Effects of pyruvate dehydrogenase subunits overexpression on the α-ketoglutarate production in Yarrowia lipolytica WSH-Z06.Whole-exome sequencing uncovers oxidoreductases DHTKD1 and OGDHL as linkers between mitochondrial dysfunction and eosinophilic esophagitis.
P2860
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P2860
Structure-function relationships in the 2-oxo acid dehydrogenase family: substrate-specific signatures and functional predictions for the 2-oxoglutarate dehydrogenase-like proteins.
description
2008 nî lūn-bûn
@nan
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Structure-function relationshi ...... e dehydrogenase-like proteins.
@ast
Structure-function relationshi ...... e dehydrogenase-like proteins.
@en
Structure-function relationshi ...... e dehydrogenase-like proteins.
@nl
type
label
Structure-function relationshi ...... e dehydrogenase-like proteins.
@ast
Structure-function relationshi ...... e dehydrogenase-like proteins.
@en
Structure-function relationshi ...... e dehydrogenase-like proteins.
@nl
prefLabel
Structure-function relationshi ...... e dehydrogenase-like proteins.
@ast
Structure-function relationshi ...... e dehydrogenase-like proteins.
@en
Structure-function relationshi ...... e dehydrogenase-like proteins.
@nl
P356
P1433
P1476
Structure-function relationshi ...... e dehydrogenase-like proteins.
@en
P2093
Dmitry Degtyarev
Victoria I Bunik
P304
P356
10.1002/PROT.21766
P407
P577
2008-05-01T00:00:00Z