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A Review of the Giant Protein Titin in Clinical Molecular Diagnostics of CardiomyopathiesThe role of titin and extracellular matrix remodelling in heart failure with preserved ejection fractionCardiomyocyte subdomain contractility arising from microenvironmental stiffness and topographyTranslation of Human-Induced Pluripotent Stem Cells: From Clinical Trial in a Dish to Precision MedicineSarcomeric protein isoform transitions in cardiac muscle: a journey to heart failureGenetic epidemiology of titin-truncating variants in the etiology of dilated cardiomyopathy.Techniques for the analysis of cysteine sulfhydryls and oxidative protein folding.Non-sirtuin histone deacetylases in the control of cardiac agingPhosphorylating Titin's Cardiac N2B Element by ERK2 or CaMKIIδ Lowers the Single Molecule and Cardiac Muscle ForcePhenotype-Specific Treatment of Heart Failure With Preserved Ejection Fraction: A Multiorgan Roadmap.Whole gene sequencing identifies deep-intronic variants with potential functional impact in patients with hypertrophic cardiomyopathy.RBM20, a potential target for treatment of cardiomyopathy via titin isoform switching.Phosphorylation of Ser283 enhances the stiffness of the tropomyosin head-to-tail overlap domain.Rare Titin (TTN) Variants in Diseases Associated with Sudden Cardiac DeathCommentary: Epigenetic Regulation of Phosphodiesterases 2A and 3A Underlies Compromised β-Adrenergic Signaling in an iPSC Model of Dilated Cardiomyopathy.Could Modification of Titin Contribute to an Answer for Heart Failure With Preserved Ejection Fraction?RBM20 is an essential factor for thyroid hormone-regulated titin isoform transition.More roles for the (passive) giant. Focus on "The increase in non-cross-bridge forces after stretch of activated striated muscle is related to titin isoforms".Sex differences in myosin heavy chain isoforms of human failing and nonfailing atria.Insulin regulates titin pre-mRNA splicing through the PI3K-Akt-mTOR kinase axis in a RBM20-dependent manner.Characterization of TTN Novex Splicing Variants across Species and the Role of RBM20 in Novex-Specific Exon Splicing.Dilated Cardiomyopathy: Genetic Determinants and Mechanisms.In Silico Analysis of Differential Gene Expression in Three Common Rat Models of Diastolic Dysfunction.Splicing Factor RBM20 Regulates Transcriptional Network of Titin Associated and Calcium Handling Genes in The Heart.Phosphorylation of the RSRSP stretch is critical for splicing regulation by RNA-Binding Motif Protein 20 (RBM20) through nuclear localization.
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description
2014 nî lūn-bûn
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2014 թուականի Մարտին հրատարակուած գիտական յօդուած
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2014 թվականի մարտին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
@zh-hk
2014年論文
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2014年論文
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2014年论文
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name
Cardiac titin and heart disease.
@ast
Cardiac titin and heart disease.
@en
Cardiac titin and heart disease.
@nl
type
label
Cardiac titin and heart disease.
@ast
Cardiac titin and heart disease.
@en
Cardiac titin and heart disease.
@nl
prefLabel
Cardiac titin and heart disease.
@ast
Cardiac titin and heart disease.
@en
Cardiac titin and heart disease.
@nl
P2860
P1476
Cardiac titin and heart disease.
@en
P2093
Henk L Granzier
Martin M LeWinter
P2860
P304
P356
10.1097/FJC.0000000000000007
P407
P577
2014-03-01T00:00:00Z