The mechanism for isopenicillin N synthase from density-functional modeling highlights the similarities with other enzymes in the 2-His-1-carboxylate family.
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The interaction of isopenicillin N synthase with homologated substrate analogues δ-(L-α-aminoadipoyl)-L-homocysteinyl-D-Xaa characterised by protein crystallographyThe crystal structure of an isopenicillin N synthase complex with an ethereal substrate analogue reveals water in the oxygen binding siteEvidence that the fosfomycin-producing epoxidase, HppE, is a non-heme-iron peroxidaseThe enzymes of β-lactam biosynthesis.Differences and comparisons of the properties and reactivities of iron(III)-hydroperoxo complexes with saturated coordination sphereHighly unsaturated binuclear butadiene iron carbonyls: quintet spin states, perpendicular structures, agostic hydrogen atoms, and iron-iron multiple bonds.Theoretical study of the mechanism of oxoiron(IV) formation from H2O2 and a nonheme iron(II) complex: O-O cleavage involving proton-coupled electron transferMechanism of extradiol aromatic ring-cleaving dioxygenases.Spectroscopic Evidence for the Two C-H-Cleaving Intermediates of Aspergillus nidulans Isopenicillin N Synthase.Theoretical studies of structure, function and reactivity of molecules--a personal account.Beyond ferryl-mediated hydroxylation: 40 years of the rebound mechanism and C-H activation.Quantum mechanics/molecular mechanics study on the oxygen binding and substrate hydroxylation step in AlkB repair enzymesProtein effects in non-heme iron enzyme catalysis: insights from multiscale models.Go it alone: four-electron oxidations by mononuclear non-heme iron enzymes.Dioxygen activation by nonheme iron enzymes with the 2-His-1-carboxylate facial triad that generate high-valent oxoiron oxidants.Reaction coordinate of isopenicillin N synthase: oxidase versus oxygenase activity.Rate-Determining Attack on Substrate Precedes Rieske Cluster Oxidation during Cis-Dihydroxylation by Benzoate DioxygenaseTerminally Truncated Isopenicillin N Synthase Generates a Dithioester Product: Evidence for a Thioaldehyde Intermediate during Catalysis and a New Mode of Reaction for Non-Heme Iron Oxidases.On the catalytic mechanism of (S)-2-hydroxypropylphosphonic acid epoxidase (HppE): a hybrid DFT study.Global stability of an α-ketoglutarate-dependent dioxygenase (TauD) and its related complexes.Artificial Force Induced Reaction Method for Systematic Determination of Complex Reaction Mechanisms.Roles of 2-oxoglutarate oxygenases and isopenicillin N synthase in β-lactam biosynthesisSpectroscopic and Electronic Structure Study of ETHE1: Elucidating the Factors Influencing Sulfur Oxidation and Oxygenation in Mononuclear Nonheme Iron Enzymes
P2860
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P2860
The mechanism for isopenicillin N synthase from density-functional modeling highlights the similarities with other enzymes in the 2-His-1-carboxylate family.
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2007 nî lūn-bûn
@nan
2007 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
The mechanism for isopenicilli ...... he 2-His-1-carboxylate family.
@ast
The mechanism for isopenicilli ...... he 2-His-1-carboxylate family.
@en
The mechanism for isopenicilli ...... he 2-His-1-carboxylate family.
@nl
type
label
The mechanism for isopenicilli ...... he 2-His-1-carboxylate family.
@ast
The mechanism for isopenicilli ...... he 2-His-1-carboxylate family.
@en
The mechanism for isopenicilli ...... he 2-His-1-carboxylate family.
@nl
prefLabel
The mechanism for isopenicilli ...... he 2-His-1-carboxylate family.
@ast
The mechanism for isopenicilli ...... he 2-His-1-carboxylate family.
@en
The mechanism for isopenicilli ...... he 2-His-1-carboxylate family.
@nl
P2093
P356
P1433
P1476
The mechanism for isopenicilli ...... he 2-His-1-carboxylate family.
@en
P2093
Keiji Morokuma
Marcus Lundberg
Per E M Siegbahn
P304
P356
10.1021/BI701577Q
P407
P577
2007-12-29T00:00:00Z