The codon 72 polymorphism of p53 regulates interaction with NF-{kappa}B and transactivation of genes involved in immunity and inflammation
about
Caught in the cross fire: p53 in inflammation.An African-specific polymorphism in the TP53 gene impairs p53 tumor suppressor function in a mouse modelEffects of prostaglandin E2 on p53 mRNA transcription and p53 mutagenesis during T-cell-independent human B-cell clonal expansionCSF1 is a novel p53 target gene whose protein product functions in a feed-forward manner to suppress apoptosis and enhance p53-mediated growth arrest.The p53 Transcriptional Network Influences Microglia Behavior and NeuroinflammationAnalysis of Tp53 codon 72 polymorphisms, Tp53 mutations, and HPV infection in cutaneous squamous cell carcinomas.Phosphorylation of p65(RelA) on Ser(547) by ATM represses NF-κB-dependent transcription of specific genes after genotoxic stress.A genetic variant of p53 restricts the mucous secretory phenotype by regulating SPDEF and Bcl-2 expression.Tissue-specific apoptotic effects of the p53 codon 72 polymorphism in a mouse model.Inflammation and p53: A Tale of Two StressesA compensatory role of NF-κB to p53 in response to 5-FU-based chemotherapy for gastric cancer cell lines.Transcriptomes and shRNA suppressors in a TP53 allele-specific model of early-onset colon cancer in African Americans.The relationship of TP53 R72P polymorphism to disease outcome and TP53 mutation in myelodysplastic syndromesp53 protects against LPS-induced lung endothelial barrier dysfunction.Association between polymorphisms in tumor suppressor genes and oncogenes and risk of hepatocellular carcinoma: a case-control study in an HCC epidemic area within the Han Chinese population.NF-κB regulates caspase-4 expression and sensitizes neuroblastoma cells to Fas-induced apoptosis.Tumor protein p63/nuclear factor κB feedback loop in regulation of cell death.Towards an understanding of the role of p53 in adrenocortical carcinogenesis.Interactions of miR-34b/c and TP53 polymorphisms on the risk of intracranial aneurysm.p53 amplifies Toll-like receptor 5 response in human primary and cancer cells through interaction with multiple signal transduction pathwaysCaspase cleavage of iASPP potentiates its ability to inhibit p53 and NF-κB.The P72R Polymorphism of p53 Predisposes to Obesity and Metabolic Dysfunction.HSP70 Inhibition Limits FAK-Dependent Invasion and Enhances the Response to Melanoma Treatment with BRAF Inhibitors.The p53 Codon 72 Polymorphism Modifies the Cellular Response to Inflammatory Challenge in the LiverAlternative Interventions to Prevent Oxidative Damage following Ischemia/ReperfusionModeling gene-environment interactions in oral cavity and esophageal cancers demonstrates a role for the p53 R72P polymorphism in modulating susceptibilityp53 and NF-κB coregulate proinflammatory gene responses in human macrophages.The diverse and complex roles of NF-κB subunits in cancer.The complexity of NF-κB signaling in inflammation and cancer.Illuminating p53 function in cancer with genetically engineered mouse models.Genetic Modifiers of the p53 Pathway.The codon 72 polymorphism of p53 influences cell fate following nutrient deprivation.Nuclear Translocation of p65 is Controlled by Sec6 via the Degradation of IκBα.Sumoylation of HDAC2 promotes NF-κB-dependent gene expression.p53 and the Carcinogenicity of Chronic Inflammation.Study of the TP53 codon 72 polymorphism in oral cancer and oral potentially malignant disorders in Argentine patients.TLR2∆22 (-196-174) significantly increases the risk of breast cancer in females carrying proline allele at codon 72 of TP53 gene: a case-control study from four ethnic groups of North Eastern region of India.Regulation of p53 and Rb links the alternative NF-κB pathway to EZH2 expression and cell senescence.Identification of TRIML2, a novel p53 target, that enhances p53 SUMOylation and regulates the transactivation of proapoptotic genes.Functional consequence of the p53 codon 72 polymorphism in colorectal cancer.
P2860
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P2860
The codon 72 polymorphism of p53 regulates interaction with NF-{kappa}B and transactivation of genes involved in immunity and inflammation
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The codon 72 polymorphism of p ...... d in immunity and inflammation
@ast
The codon 72 polymorphism of p ...... d in immunity and inflammation
@en
The codon 72 polymorphism of p ...... d in immunity and inflammation
@nl
type
label
The codon 72 polymorphism of p ...... d in immunity and inflammation
@ast
The codon 72 polymorphism of p ...... d in immunity and inflammation
@en
The codon 72 polymorphism of p ...... d in immunity and inflammation
@nl
prefLabel
The codon 72 polymorphism of p ...... d in immunity and inflammation
@ast
The codon 72 polymorphism of p ...... d in immunity and inflammation
@en
The codon 72 polymorphism of p ...... d in immunity and inflammation
@nl
P2093
P2860
P356
P1476
The codon 72 polymorphism of p ...... d in immunity and inflammation
@en
P2093
Amanda K Frank
Andres Klein-Szanto
Julia I-Ju Leu
Karthik Devarajan
Maureen E Murphy
Monica Hollstein
Tatiana Nedelko
P2860
P304
P356
10.1128/MCB.01136-10
P407
P577
2011-01-18T00:00:00Z