Multiple functional therapeutic effects of the estrogen receptor β agonist indazole-Cl in a mouse model of multiple sclerosis
about
Design of pathway preferential estrogens that provide beneficial metabolic and vascular effects without stimulating reproductive tissuesNudging oligodendrocyte intrinsic signaling to remyelinate and repair: Estrogen receptor ligand effects.Inhibition of Drp1 hyper-activation is protective in animal models of experimental multiple sclerosis.Transplantation of Neural Stem Cells Cotreated with Thyroid Hormone and GDNF Gene Induces Neuroprotection in Rats of Chronic Experimental Allergic Encephalomyelitis.Clobetasol promotes remyelination in a mouse model of neuromyelitis opticaMultiple sclerosis patients have a distinct gut microbiota compared to healthy controlsTamoxifen accelerates the repair of demyelinated lesions in the central nervous system.Intracellular signaling pathway regulation of myelination and remyelination in the CNS.Estrogens, Neuroinflammation, and Neurodegeneration.IL-17-triggered downregulation of miR-497 results in high HIF-1α expression and consequent IL-1β and IL-6 production by astrocytes in EAE mice.A mouse model for testing remyelinating therapies.The promyelinating properties of androstenediol in gliotoxin-induced demyelination in rat corpus callosum.Metabolic pathways as possible therapeutic targets for progressive multiple sclerosis.Bedside to bench to bedside research: Estrogen receptor beta ligand as a candidate neuroprotective treatment for multiple sclerosis.Chronic demyelination-induced seizures.Oestrogen receptor β ligand acts on CD11c+ cells to mediate protection in experimental autoimmune encephalomyelitis.Interactions Between the Canonical WNT/Beta-Catenin Pathway and PPAR Gamma on Neuroinflammation, Demyelination, and Remyelination in Multiple Sclerosis.ERβ-Dependent Direct Suppression of Human and Murine Th17 Cells and Treatment of Established Central Nervous System Autoimmunity by a Neurosteroid.Prior regular exercise improves clinical outcome and reduces demyelination and axonal injury in experimental autoimmune encephalomyelitis.Consistent induction of chronic experimental autoimmune encephalomyelitis in C57BL/6 mice for the longitudinal study of pathology and repair.ERβ in CD4+ T Cells Is Crucial for Ligand-Mediated Suppression of Central Nervous System Autoimmunity.[New therapeutic strategies for remyelination in multiple sclerosis].Increase in chemokine CXCL1 by ERβ ligand treatment is a key mediator in promoting axon myelination.
P2860
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P2860
Multiple functional therapeutic effects of the estrogen receptor β agonist indazole-Cl in a mouse model of multiple sclerosis
description
2014 nî lūn-bûn
@nan
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Multiple functional therapeuti ...... se model of multiple sclerosis
@ast
Multiple functional therapeuti ...... se model of multiple sclerosis
@en
Multiple functional therapeuti ...... se model of multiple sclerosis
@nl
type
label
Multiple functional therapeuti ...... se model of multiple sclerosis
@ast
Multiple functional therapeuti ...... se model of multiple sclerosis
@en
Multiple functional therapeuti ...... se model of multiple sclerosis
@nl
prefLabel
Multiple functional therapeuti ...... se model of multiple sclerosis
@ast
Multiple functional therapeuti ...... se model of multiple sclerosis
@en
Multiple functional therapeuti ...... se model of multiple sclerosis
@nl
P2093
P2860
P356
P1476
Multiple functional therapeuti ...... se model of multiple sclerosis
@en
P2093
Anna J Khalaj
JaeHee Yoon
John A Katzenellenbogen
Leonardo Martinez-Torres
Norio Yasui
Seema Kaushalya Tiwari-Woodruff
Shalini Kumar
Timothy Yoo
Zachary Winchester
P2860
P304
18061-18066
P356
10.1073/PNAS.1411294111
P407
P577
2014-12-01T00:00:00Z