Stargazin controls the pharmacology of AMPA receptor potentiators.
about
Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteinsStructural and Functional Analysis of Two New Positive Allosteric Modulators of GluA2 Desensitization and DeactivationStructural analysis of the positive AMPA receptor modulators CX516 and Me-CX516 in complex with the GluA2 ligand-binding domainFrom synapse to nucleus: novel targets for treating depression.A charge-inverting mutation in the "linker" region of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors alters agonist binding and gating kinetics independently of allosteric modulators.Lithium acts as a potentiator of AMPAR currents in hippocampal CA1 cells by selectively increasing channel open probability.Serine racemase regulated by binding to stargazin and PSD-95: potential N-methyl-D-aspartate-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (NMDA-AMPA) glutamate neurotransmission cross-talk.Autoinactivation of the stargazin-AMPA receptor complex: subunit-dependency and independence from physical dissociation.Stargazin interaction with alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors is critically dependent on the amino acid at the narrow constriction of the ion channel.AMPA receptor potentiators: from drug design to cognitive enhancementThe stoichiometry of AMPA receptors and TARPs varies by neuronal cell type.Novel toxicity of the unedited GluR2 AMPA receptor subunit dependent on surface trafficking and increased Ca2+-permeability.AMPA receptors and stargazin-like transmembrane AMPA receptor-regulatory proteins mediate hippocampal kainate neurotoxicity.Screening for AMPA receptor auxiliary subunit specific modulators.Glutamate mediates platelet activation through the AMPA receptor.α/β-Hydrolase domain-containing 6 (ABHD6) negatively regulates the surface delivery and synaptic function of AMPA receptors.The role of transmembrane AMPA receptor regulatory proteins (TARPs) in neurotransmission and receptor trafficking (Review).Regulation of AMPA receptor gating and pharmacology by TARP auxiliary subunits.Evolutionary conserved role for TARPs in the gating of glutamate receptors and tuning of synaptic function.Transmembrane AMPA receptor regulatory proteins and AMPA receptor function in the cerebellumModulation of agonist binding to AMPA receptors by 1-(1,4-benzodioxan-6-ylcarbonyl)piperidine (CX546): differential effects across brain regions and GluA1-4/transmembrane AMPA receptor regulatory protein combinations.The Inhibitory Effect of α/β-Hydrolase Domain-Containing 6 (ABHD6) on the Surface Targeting of GluA2- and GluA3-Containing AMPA Receptors.Regulation of ionotropic glutamate receptors by their auxiliary subunits.AKAP signaling complexes in regulation of excitatory synaptic plasticityThe regulation of glutamate receptor trafficking and function by TARPs and other transmembrane auxiliary subunits.Integrin regulation of cytoplasmic calcium in excitatory neurons depends upon glutamate receptors and release from intracellular storesMapping the interaction sites between AMPA receptors and TARPs reveals a role for the receptor N-terminal domain in channel gating.TARP phosphorylation regulates synaptic AMPA receptors through lipid bilayers.Activity-mediated AMPA receptor remodeling, driven by alternative splicing in the ligand-binding domainTransmembrane AMPA receptor regulatory proteins and cornichon-2 allosterically regulate AMPA receptor antagonists and potentiatorsHippocampal GluA2 and GluA4 protein but not corresponding mRNA and promoter methylation levels are modulated at retrieval in spatial learning of the rat.
P2860
Q24318579-6337293A-3678-4ED3-9FBD-000747AD2D18Q27667701-72CB16BA-E877-429E-89F6-6DC4C97B7D49Q27685440-40E212C7-A0E8-48C4-B213-5F4A7D2A3055Q33653177-A4AD92C1-46E1-4912-AF02-42C5EA339BE0Q33675838-D2FD7697-0EC0-4F9A-84F3-708AC66D6FF3Q34135203-3E737AF1-D92A-48E6-AD23-11033B6DB929Q34396776-F9A201BD-5ED1-4DF4-B929-5B4FEAEF430CQ34482167-F3C33D83-424A-4191-AD0A-531EC25A7A18Q34625854-5287E2C3-A94C-44D9-B41C-A10F92940C63Q35054673-3BC1A452-95D2-4782-B906-64EE2C1BDFC8Q35058328-08305A32-6DFA-4B11-A10D-079CFDAD29ECQ36074474-B83E3A0C-20C6-4A0D-81F6-A3EE15E68E45Q36277019-4C1615FF-A8C7-46A6-A6BA-6C18700326C4Q36328451-E856D4A4-886B-4DA2-9DF2-558595096FE6Q36509851-E76F6DE8-A4E8-4664-B8DE-68098B223191Q36905084-72C11FF7-E15A-459E-A0FB-3AF61CAEA094Q37150938-56D14F0E-7F7A-40DC-900F-35A214D47C04Q37178076-A50C249B-3354-4F14-8821-3EC1FEAFFF04Q37369634-5B142DF2-AC45-4557-87A0-1483B02D32BCQ37382484-DB06C8C8-2B8D-4908-8739-E0292509A419Q37444397-09105347-6544-4E4D-BFD3-C315568EE03CQ37676911-496998CE-A255-4F98-BD1E-150224E05DA0Q37687731-E4A09919-10FB-45A3-A202-D33243244A22Q37865993-8B3F9B70-B3B1-488C-9690-59B2C98B6F6DQ37945010-3346CC62-5A01-42A0-8EE3-DEBCCBA0C529Q38619347-9CF3E826-9304-4E55-98FB-41F230962016Q39856314-63D09F1D-DA0B-4DD9-AE70-4E20B2F418E6Q41153177-282CE217-A368-43ED-8873-D38E0B6E4305Q41431751-98EBF1A1-96BA-4C03-AA77-47D5241A90ACQ41958491-C5CFFBEB-CE12-4D7A-BE47-FF9BB3B9FD18Q48485500-C10C09D0-58BD-4AA5-81FB-058C1B081FC8
P2860
Stargazin controls the pharmacology of AMPA receptor potentiators.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Stargazin controls the pharmacology of AMPA receptor potentiators.
@ast
Stargazin controls the pharmacology of AMPA receptor potentiators.
@en
Stargazin controls the pharmacology of AMPA receptor potentiators.
@nl
type
label
Stargazin controls the pharmacology of AMPA receptor potentiators.
@ast
Stargazin controls the pharmacology of AMPA receptor potentiators.
@en
Stargazin controls the pharmacology of AMPA receptor potentiators.
@nl
prefLabel
Stargazin controls the pharmacology of AMPA receptor potentiators.
@ast
Stargazin controls the pharmacology of AMPA receptor potentiators.
@en
Stargazin controls the pharmacology of AMPA receptor potentiators.
@nl
P2093
P2860
P356
P1476
Stargazin controls the pharmacology of AMPA receptor potentiators.
@en
P2093
David S Bredt
Keiji Wada
Masayuki Sekiguchi
Roger A Nicoll
Susumu Tomita
P2860
P304
10064-10067
P356
10.1073/PNAS.0603128103
P407
P577
2006-06-19T00:00:00Z