Design of small molecule-responsive microRNAs based on structural requirements for Drosha processing. - Test2 - elhamkhani - TriplyDB

Design of small molecule-responsive microRNAs based on structural requirements for Drosha processing.

Design of small molecule-responsive microRNAs based on structural requirements for Drosha processing.

http://www.wikidata.org/entity/Q34779516

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Opportunities in the design and application of RNA for gene expression control Regulation of MAP4K4 gene expression by RNA interference through an engineered theophylline-dependent hepatitis delta virus ribozyme switch.Conditional Dicer substrate formation via shape and sequence transduction with small conditional RNAs.Engineering ligand-responsive RNA controllers in yeast through the assembly of RNase III tuning modules.Modular construction of mammalian gene circuits using TALE transcriptional repressors.Synthetic feedback control using an RNAi-based gene-regulatory device.From DNA to targeted therapeutics: bringing synthetic biology to the clinic.Synthetic biology: advancing biological frontiers by building synthetic systems Synthetic RNA switches as a tool for temporal and spatial control over gene expression.Twins, quadruplexes, and more: functional aspects of native and engineered RNA self-assembly in vivo Theophylline controllable RNAi-based genetic switches regulate expression of lncRNA TINCR and malignant phenotypes in bladder cancer cells Tuning response curves for synthetic biology.Rational design of a synthetic mammalian riboswitch as a ligand-responsive -1 ribosomal frame-shifting stimulator Association of a peptoid ligand with the apical loop of pri-miR-21 inhibits cleavage by Drosha.Recombinant AAV as a platform for translating the therapeutic potential of RNA interference.Engineering biological systems with synthetic RNA molecules.RNA-based therapeutics: current progress and future prospects.Synthetic biology: advancing the design of diverse genetic systems RNA modularity for synthetic biology.Endless: a purine-binding RNA motif that can be expressed in cells.Synthetic biology devices and circuits for RNA-based 'smart vaccines': a propositional review.Mammalian synthetic biology: emerging medical applications.Naringenin-responsive riboswitch-based fluorescent biosensor module for Escherichia coli co-cultures.Synthetic biology: applying biological circuits beyond novel therapies.Synthetic Biology-The Synthesis of Biology.RNA-based gene circuits for cell regulation.Artificial nucleobase-amino acid conjugates: a new class of TAR RNA binding agents.A yeast-based rapid prototype platform for gene control elements in mammalian cells.Inducible Bcl-2 gene RNA interference mediated by aptamer-integrated HDV ribozyme switch.A quantitative framework for the forward design of synthetic miRNA circuits.Rational design of allosteric inhibitors and activators using the population-shift model: in vitro validation and application to an artificial biosensor.Selection of tetracycline inducible self-cleaving ribozymes as synthetic devices for gene regulation in yeast.Regulation of T cell proliferation with drug-responsive microRNA switches.Synthetic Gene Expression Circuits for Designing Precision Tools in Oncology.Synthetic mammalian riboswitches based on guanine aptazyme.Design and implementation of a synthetic pre-miR switch for controlling miRNA biogenesis in mammals.Synthetic Gene Expression Circuits for Designing Precision Tools in Oncology.A structural map of oncomiR-1 at single-nucleotide resolution.Synthesizing artificial devices that redirect cellular information at will.

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Design of small molecule-responsive microRNAs based on structural requirements for Drosha processing.

http://www.wikidata.org/entity/Q34779516

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2010 nî lūn-bûn

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2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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Design of small molecule-respo ...... rements for Drosha processing.

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Design of small molecule-respo ...... rements for Drosha processing.

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Design of small molecule-respo ...... rements for Drosha processing.

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Design of small molecule-respo ...... rements for Drosha processing.

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Design of small molecule-respo ...... rements for Drosha processing.

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Christina D Smolke

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Kevin G Hoff

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Stephanie J Culler

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Yvonne Y Chen

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P2860

The nuclear RNase III Drosha initiates microRNA processing

RNA-binding protein Dnd1 inhibits microRNA access to target mRNA

The Microprocessor complex mediates the genesis of microRNAs

The Drosha-DGCR8 complex in primary microRNA processing

MicroRNA maturation: stepwise processing and subcellular localization.

Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs

Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha

Most mammalian mRNAs are conserved targets of microRNAs

Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imaging

Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells

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