Stably paused genes revealed through inhibition of transcription initiation by the TFIIH inhibitor triptolide
about
Getting up to speed with transcription elongation by RNA polymerase IITFIIH: New Discoveries Regarding its Mechanisms and Impact on Cancer TreatmentRNA polymerase II pausing can be retained or acquired during activation of genes involved in the epithelial to mesenchymal transition.Genome-wide association analysis identified splicing single nucleotide polymorphism in CFLAR predictive of triptolide chemo-sensitivity.Drosophila TDP-43 RNA-Binding Protein Facilitates Association of Sister Chromatid Cohesion Proteins with Genes, Enhancers and Polycomb Response Elements.PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase IIRNA polymerase II pausing as a context-dependent reader of the genome.Fabrication of novel vesicles of triptolide for antirheumatoid activity with reduced toxicity in vitro and in vivo.Ready, pause, go: regulation of RNA polymerase II pausing and release by cellular signaling pathwaysTherapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas.Mitotic Transcriptional Activation: Clearance of Actively Engaged Pol II via Transcriptional Elongation Control in Mitosis.Human TFIIH Kinase CDK7 Regulates Transcription-Associated Chromatin Modifications.Is TFIIH the new Achilles heel of cancer cells?Oxidative stress rapidly stabilizes promoter-proximal paused Pol II across the human genome.Global unleashing of transcription elongation waves in response to genotoxic stress restricts somatic mutation rate.Critical Role of Hepatic Cyp450s in the Testis-Specific Toxicity of (5R)-5-Hydroxytriptolide in C57BL/6 Mice.PAF1 regulation of promoter-proximal pause release via enhancer activation.Chromatin dependencies in cancer and inflammation.Widespread transcriptional pausing and elongation control at enhancers.Measuring Nascent Transcripts by Nascent-seq.RNA Pol II Dynamics Modulate Co-transcriptional Chromatin Modification, CTD Phosphorylation, and Transcriptional Direction.Paused RNA polymerase II inhibits new transcriptional initiation.Mitochondrial Retrograde Signaling in Mammals Is Mediated by the Transcriptional Cofactor GPS2 via Direct Mitochondria-to-Nucleus TranslocationThe essential and multi-functional TFIIH complex.Live-cell analysis of endogenous GFP-RPB1 uncovers rapid turnover of initiating and promoter-paused RNA Polymerase II.Argonaute2 attenuates active transcription by limiting RNA Polymerase II elongation in Drosophila melanogaster
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P2860
Stably paused genes revealed through inhibition of transcription initiation by the TFIIH inhibitor triptolide
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2015 nî lūn-bûn
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2015 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2015 թվականի հունվարին հրատարակված գիտական հոդված
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年论文
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Stably paused genes revealed t ...... the TFIIH inhibitor triptolide
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Stably paused genes revealed t ...... the TFIIH inhibitor triptolide
@en
Stably paused genes revealed t ...... the TFIIH inhibitor triptolide
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label
Stably paused genes revealed t ...... the TFIIH inhibitor triptolide
@ast
Stably paused genes revealed t ...... the TFIIH inhibitor triptolide
@en
Stably paused genes revealed t ...... the TFIIH inhibitor triptolide
@nl
prefLabel
Stably paused genes revealed t ...... the TFIIH inhibitor triptolide
@ast
Stably paused genes revealed t ...... the TFIIH inhibitor triptolide
@en
Stably paused genes revealed t ...... the TFIIH inhibitor triptolide
@nl
P2093
P2860
P356
P1433
P1476
Stably paused genes revealed t ...... the TFIIH inhibitor triptolide
@en
P2093
Ali Shilatifard
P2860
P356
10.1101/GAD.246173.114
P577
2015-01-01T00:00:00Z