Two neuronal nicotinic acetylcholine receptors, alpha4beta4 and alpha7, show differential agonist binding modes.
about
Principles of agonist recognition in Cys-loop receptorsFunctional probes of drug-receptor interactions implicated by structural studies: Cys-loop receptors provide a fertile testing groundThe binding orientation of epibatidine at α7 nACh receptorsSelective ligand behaviors provide new insights into agonist activation of nicotinic acetylcholine receptors.Differential expression and function of nicotinic acetylcholine receptors in subdivisions of medial habenulaFunctional evaluation of key interactions evident in the structure of the eukaryotic Cys-loop receptor GluCl.Insights into a highly conserved network of hydrogen bonds in the agonist binding site of nicotinic acetylcholine receptors: a structural and theoretical study.Evidence for an extended hydrogen bond network in the binding site of the nicotinic receptor: role of the vicinal disulfide of the alpha1 subunit.Potential state-selective hydrogen bond formation can modulate activation and desensitization of the α7 nicotinic acetylcholine receptorVariations in binding among several agonists at two stoichiometries of the neuronal, α4β2 nicotinic receptor.Synthesis of selective agonists for the α7 nicotinic acetylcholine receptor with in situ click-chemistry on acetylcholine-binding protein templates.A coupled array of noncovalent interactions impacts the function of the 5-HT3A serotonin receptor in an agonist-specific way.Multiple cholinergic signaling pathways in pituitary gonadotrophs.An unusual pattern of ligand-receptor interactions for the α7 nicotinic acetylcholine receptor, with implications for the binding of varenicline.Crystal structure of a human neuronal nAChR extracellular domain in pentameric assembly: Ligand-bound α2 homopentamerIdentifying key amino acid residues that affect α-conotoxin AuIB inhibition of α3β4 nicotinic acetylcholine receptors.Incorporation of Non-Canonical Amino Acids.Varenicline Interactions at the 5-HT3 Receptor Ligand Binding Site are Revealed by 5-HTBPProbing the non-canonical interface for agonist interaction with an α5 containing nicotinic acetylcholine receptor.Probing the effects of residues located outside the agonist binding site on drug-receptor selectivity in the nicotinic receptor.An Unaltered Orthosteric Site and a Network of Long-Range Allosteric Interactions for PNU-120596 in α7 Nicotinic Acetylcholine Receptors.Probing for and Quantifying Agonist Hydrogen Bonds in α6β2 Nicotinic Acetylcholine Receptors.Competitive docking model for prediction of the human nicotinic acetylcholine receptor α7 binding of tobacco constituents.Binding of imidacloprid, thiamethoxam and N-desmethylthiamethoxam to nicotinic receptors of Myzus persicae: pharmacological profiling using neonicotinoids, natural agonists and antagonists.
P2860
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P2860
Two neuronal nicotinic acetylcholine receptors, alpha4beta4 and alpha7, show differential agonist binding modes.
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Two neuronal nicotinic acetylc ...... rential agonist binding modes.
@ast
Two neuronal nicotinic acetylc ...... rential agonist binding modes.
@en
Two neuronal nicotinic acetylc ...... rential agonist binding modes.
@nl
type
label
Two neuronal nicotinic acetylc ...... rential agonist binding modes.
@ast
Two neuronal nicotinic acetylc ...... rential agonist binding modes.
@en
Two neuronal nicotinic acetylc ...... rential agonist binding modes.
@nl
prefLabel
Two neuronal nicotinic acetylc ...... rential agonist binding modes.
@ast
Two neuronal nicotinic acetylc ...... rential agonist binding modes.
@en
Two neuronal nicotinic acetylc ...... rential agonist binding modes.
@nl
P2093
P2860
P356
P1476
Two neuronal nicotinic acetylc ...... erential agonist binding modes
@en
P2093
Dennis A Dougherty
Nyssa L Puskar
P2860
P304
14618-14627
P356
10.1074/JBC.M110.206565
P407
P50
P577
2011-02-22T00:00:00Z