The Josephin domain determines the morphological and mechanical properties of ataxin-3 fibrils.
about
The role of the central flexible region on the aggregation and conformational properties of human ataxin-3Josephin Domain Structural Conformations Explored by Metadynamics in Essential Coordinates.A hydrophobic gold surface triggers misfolding and aggregation of the amyloidogenic Josephin domain in monomeric form, while leaving the oligomers unaffectedHsp104 suppresses polyglutamine-induced degeneration post onset in a drosophila MJD/SCA3 model.Energy landscapes of functional proteins are inherently risky.Toward understanding Machado-Joseph diseaseInfrared nanospectroscopy characterization of oligomeric and fibrillar aggregates during amyloid formation.Enhanced molecular mobility of ordinarily structured regions drives polyglutamine diseaseThermodynamic and kinetic stability of the Josephin Domain closed arrangement: evidences from replica exchange molecular dynamicsAtaxin-3 protein and RNA toxicity in spinocerebellar ataxia type 3: current insights and emerging therapeutic strategies.Examination of Ataxin-3 (atx-3) Aggregation by Structural Mass Spectrometry Techniques: A Rationale for Expedited Aggregation upon Polyglutamine (polyQ) Expansion.MJD and OTU deubiquitinating enzymes in Schistosoma mansoni.A tale of a tail: Structural insights into the conformational properties of the polyglutamine protein ataxin-3.Natural compounds against neurodegenerative diseases: molecular characterization of the interaction of catechins from green tea with Aβ1-42, PrP106-126, and ataxin-3 oligomers.Unbiased screen identifies aripiprazole as a modulator of abundance of the polyglutamine disease protein, ataxin-3.Identification of a novel site of interaction between ataxin-3 and the amyloid aggregation inhibitor polyglutamine binding peptide 1.Destabilizing the AXH Tetramer by Mutations: Mechanisms and Potential Antiaggregation Strategies.A hypothetical hierarchical mechanism of the self-assembly of the Escherichia coli RNA polymerase σ(70) subunit.
P2860
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P2860
The Josephin domain determines the morphological and mechanical properties of ataxin-3 fibrils.
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The Josephin domain determines ...... roperties of ataxin-3 fibrils.
@ast
The Josephin domain determines ...... roperties of ataxin-3 fibrils.
@en
The Josephin domain determines ...... roperties of ataxin-3 fibrils.
@nl
type
label
The Josephin domain determines ...... roperties of ataxin-3 fibrils.
@ast
The Josephin domain determines ...... roperties of ataxin-3 fibrils.
@en
The Josephin domain determines ...... roperties of ataxin-3 fibrils.
@nl
prefLabel
The Josephin domain determines ...... roperties of ataxin-3 fibrils.
@ast
The Josephin domain determines ...... roperties of ataxin-3 fibrils.
@en
The Josephin domain determines ...... roperties of ataxin-3 fibrils.
@nl
P2093
P2860
P1433
P1476
The Josephin domain determines ...... roperties of ataxin-3 fibrils.
@en
P2093
Alfonso De Simone
Giuseppe Nicastro
Justin Molloy
Laura Masino
Lesley Calder
P2860
P304
P356
10.1016/J.BPJ.2011.02.056
P407
P577
2011-04-01T00:00:00Z