The Ras/Raf/MEK/extracellular signal-regulated kinase pathway induces autocrine-paracrine growth inhibition via the leukemia inhibitory factor/JAK/STAT pathway.
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Loss of the VHR dual-specific phosphatase causes cell-cycle arrest and senescenceSTAT3 negatively regulates thyroid tumorigenesisExogenous leukemia inhibitory factor (LIF) attenuates retinal vascularization reducing cell proliferation not apoptosisIdentification of functional modules that correlate with phenotypic difference: the influence of network topology.Three LIF-dependent signatures and gene clusters with atypical expression profiles, identified by transcriptome studies in mouse ES cells and early derivativesMedullary thyroid carcinoma: targeted therapies and future directionsTransforming growth factor-{beta} coordinately induces suppressor of cytokine signaling 3 and leukemia inhibitory factor to suppress osteoclast apoptosis.Growth arrest signaling of the Raf/MEK/ERK pathway in cancer.Focal adhesion kinase, a downstream mediator of Raf-1 signaling, suppresses cellular adhesion, migration, and neuroendocrine markers in BON carcinoid cellsClinical relevance of KRAS in human cancers.Tumour cells expressing single VEGF isoforms display distinct growth, survival and migration characteristicsLeukemia inhibitory factor in rat fetal lung development: expression and functional studiesUsing optogenetics to interrogate the dynamic control of signal transmission by the Ras/Erk module.Signaling mechanisms in neuroendocrine tumors as targets for therapy.Recombinant leukemia inhibitory factor suppresses human medullary thyroid carcinoma cell line xenografts in mice.Regulation and function of trefoil factor family 3 expression in the biliary tree.LIF upregulates expression of NK-1R in NHBE cells.The Raf/MEK/extracellular signal-regulated kinase 1/2 pathway can mediate growth inhibitory and differentiation signaling via androgen receptor downregulation in prostate cancer cells.Glycoprotein 130 regulates bone turnover and bone size by distinct downstream signaling pathways.JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis.The teratogenicity and the action mechanism of gallic acid relating with brain and cervical musclesMortalin (GRP75/HSPA9) upregulation promotes survival and proliferation of medullary thyroid carcinoma cells.Phosphoinositide and Erk signaling pathways mediate activity-driven rodent olfactory sensory neuronal survival and stress mitigationA novel U-STAT3-dependent mechanism mediates the deleterious effects of chronic nicotine exposure on renal injury.A Key Role for Leukemia Inhibitory Factor in C26 Cancer Cachexia.High LIFr expression stimulates melanoma cell migration and is associated with unfavorable prognosis in melanoma.Mouse mammary tumors display Stat3 activation dependent on leukemia inhibitory factor signalingSelective Mitochondrial Uptake of MKT-077 Can Suppress Medullary Thyroid Carcinoma Cell Survival In Vitro and In VivoMitochondria-targeted nitroxide, Mito-CP, suppresses medullary thyroid carcinoma cell survival in vitro and in vivo.Tumor suppressor role of notch1 and raf-1 signaling in medullary thyroid cancer cells.Phase II trial of sorafenib in metastatic thyroid cancerComparison of epigenetic profiles of human oral epithelial cells from HIV-positive (on HAART) and HIV-negative subjectsNeural stem cells secrete factors facilitating brain regeneration upon constitutive Raf-Erk activation.Development of a malignancy-associated proteomic signature for diffuse large B-cell lymphoma.KRASG12 mutant induces the release of the WSTF/NRG3 complex, and contributes to an oncogenic paracrine signaling pathway.The Role of STAT3 in Thyroid Cancer.IFI16 is an essential mediator of growth inhibition, but not differentiation, induced by the leukemia inhibitory factor/JAK/STAT pathway in medullary thyroid carcinoma cells.Small proline-rich proteins 2 are noncoordinately upregulated by IL-6/STAT3 signaling after bile duct ligation.Requirement for Ras/Raf/ERK pathway in naringin-induced G1-cell-cycle arrest via p21WAF1 expression.Vandetanib and cabozantinib potentiate mitochondria-targeted agents to suppress medullary thyroid carcinoma cells.
P2860
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P2860
The Ras/Raf/MEK/extracellular signal-regulated kinase pathway induces autocrine-paracrine growth inhibition via the leukemia inhibitory factor/JAK/STAT pathway.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
The Ras/Raf/MEK/extracellular ...... itory factor/JAK/STAT pathway.
@ast
The Ras/Raf/MEK/extracellular ...... itory factor/JAK/STAT pathway.
@en
The Ras/Raf/MEK/extracellular ...... itory factor/JAK/STAT pathway.
@nl
type
label
The Ras/Raf/MEK/extracellular ...... itory factor/JAK/STAT pathway.
@ast
The Ras/Raf/MEK/extracellular ...... itory factor/JAK/STAT pathway.
@en
The Ras/Raf/MEK/extracellular ...... itory factor/JAK/STAT pathway.
@nl
prefLabel
The Ras/Raf/MEK/extracellular ...... itory factor/JAK/STAT pathway.
@ast
The Ras/Raf/MEK/extracellular ...... itory factor/JAK/STAT pathway.
@en
The Ras/Raf/MEK/extracellular ...... itory factor/JAK/STAT pathway.
@nl
P2093
P2860
P1476
The Ras/Raf/MEK/extracellular ...... itory factor/JAK/STAT pathway.
@en
P2093
Barry D Nelkin
Christopher J Strock
Douglas W Ball
Jong-In Park
P2860
P304
P356
10.1128/MCB.23.2.543-554.2003
P407
P577
2003-01-01T00:00:00Z