The HCMV gH/gL/UL128-131 complex triggers the specific cellular activation required for efficient viral internalization into target monocytes.
about
Virion Glycoprotein-Mediated Immune Evasion by Human Cytomegalovirus: a Sticky Virus Makes a Slick GetawayCellular defense against latent colonization foiled by human cytomegalovirus UL138 protein.Decoding protein networks during virus entry by quantitative proteomicsCytomegalovirus, Macrophages and Breast Cancer.LPS promotes a monocyte phenotype permissive for human cytomegalovirus immediate-early gene expression upon infection but not reactivation from latencyA viral regulator of glycoprotein complexes contributes to human cytomegalovirus cell tropism.Non-redundant and redundant roles of cytomegalovirus gH/gL complexes in host organ entry and intra-tissue spread.Human Cytomegalovirus UL135 and UL136 Genes Are Required for Postentry Tropism in Endothelial Cells.Scanning Mutagenesis of Human Cytomegalovirus Glycoprotein gH/gL.Human Cytomegalovirus gH/gL/gO Promotes the Fusion Step of Entry into All Cell Types, whereas gH/gL/UL128-131 Broadens Virus Tropism through a Distinct Mechanism.A Homolog Pentameric Complex Dictates Viral Epithelial Tropism, Pathogenicity and Congenital Infection Rate in Guinea Pig CytomegalovirusHuman cytomegalovirus glycoprotein complex gH/gL/gO uses PDGFR-α as a key for entry.Human Cytomegalovirus Promotes Survival of Infected Monocytes via a Distinct Temporal Regulation of Cellular Bcl-2 Family Proteins.Viral binding-induced signaling drives a unique and extended intracellular trafficking pattern during infection of primary monocytes.Cell Surface THY-1 Contributes to Human Cytomegalovirus Entry via a Macropinocytosis-Like ProcessHCMV reprogramming of infected monocyte survival and differentiation: a Goldilocks phenomenon.Rho'ing in and out of cells: viral interactions with Rho GTPase signalingDevelopment of a high-content screen for the identification of inhibitors directed against the early steps of the cytomegalovirus infectious cycle.A role for 3-O-sulfated heparan sulfate in promoting human cytomegalovirus infection in human iris cells.Human Cytomegalovirus Requires Epidermal Growth Factor Receptor Signaling To Enter and Initiate the Early Steps in the Establishment of Latency in CD34+ Human Progenitor Cells.Chemokines encoded by herpesviruses.Two glycosaminoglycan-binding domains of the mouse cytomegalovirus-encoded chemokine MCK-2 are critical for oligomerization of the full-length protein.Host protein Snapin interacts with human cytomegalovirus pUL130 and affects viral DNA replication.HCMV Induces Macropinocytosis for Host Cell Entry in Fibroblasts.Pseudorabies virus triggers glycoprotein gE-mediated ERK1/2 activation and ERK1/2-dependent migratory behavior in T cells.HCMV utilizes a non-traditional STAT1 activation cascade via signaling through EGFR and integrins to efficiently promote the motility, differentiation, and polarization of infected monocytes.Mck2-dependent infection of alveolar macrophages promotes replication of MCMV in nodular inflammatory foci of the neonatal lung.Expression levels of glycoprotein O (gO) vary between strains of human cytomegalovirus, influencing the assembly of gH/gL complexes and virion infectivity.CD147 Promotes Entry of Pentamer-Expressing Human Cytomegalovirus into Epithelial and Endothelial Cells.HCMV Infection and Apoptosis: How Do Monocytes Survive HCMV Infection?Molecular Determinants and the Regulation of Human Cytomegalovirus Latency and Reactivation
P2860
Q26745798-577AFC82-FE13-4BF3-9833-FDFC6EC59652Q27335160-2E6CBE6A-465E-4314-BB57-B7721558DDEBQ27469058-9D87245A-5917-40B4-9693-D7701AF9CE20Q33645055-0A2357FD-9F0A-4985-B2D6-8B61BD0960D6Q33678265-96EDB941-A56D-4481-B73E-DDAF9F3BD711Q35378089-91087EF0-C25E-4B79-BB97-307C4BF30253Q35557176-257517AC-5510-4226-B718-53F9A9310CABQ35745418-756BAAC3-73B7-434B-AAF6-AF08ACD6075CQ35866191-97422A1B-AA79-493E-BAF1-75EA5AE07D38Q35913890-A87E9B09-4A12-4EE6-B859-E1AD3FE83FD5Q36069719-CAB99E5F-1F17-4FEB-B1F9-9812DFAA66E6Q36344878-0AB69F51-9984-441F-ABC0-1DDDA7CB9B86Q36736892-F82D44CE-2B5E-4894-9EF5-AFBD56D5AF77Q37161687-E90DD491-240A-4D0C-A8CE-5C5B6B85949DQ37347325-05199432-976B-432A-9CAB-6796FE9E447AQ37611836-89B6BC9E-14D0-4D59-8368-3CC05F38E987Q38201237-55C39863-8D69-4561-9F8C-BC7F0D31E4E1Q38935626-2DE1BA59-99F1-4DD7-92A6-97FF27198E06Q39035259-67C4BA37-6B1A-4790-B622-4E6AB27469B1Q39100413-AE7ADC7B-62EE-4E2C-999A-379176ECB7D7Q40067378-077A4639-04F5-4A03-9DCC-C88184A2A735Q40232348-6B9B4383-3C61-4DB5-80BD-8C929635817AQ40653356-E840CBC4-0AB3-4261-B42D-41F4E7C51FAFQ40877837-652C481D-1BA9-49D2-B229-642EB7A5B27CQ41619411-2EE0D486-EE09-491E-AD7E-B81D01615C5CQ41918747-D470E4B6-AC98-492D-BE12-FF6382DCDD4EQ42214782-17DC97A7-E660-4644-8481-BC6816E85C17Q54216733-0F486E23-9B86-4BBC-AE42-B2F98A99DFAAQ54217767-01FF0244-8E79-431C-8983-A95A56AB6D5BQ57065814-D6F2DE5E-2E67-4BB1-BD85-C8EDCA00050CQ58734475-87CB8B61-70A3-499C-AFFB-84ABB9073581
P2860
The HCMV gH/gL/UL128-131 complex triggers the specific cellular activation required for efficient viral internalization into target monocytes.
description
2013 nî lūn-bûn
@nan
2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
The HCMV gH/gL/UL128-131 compl ...... ization into target monocytes.
@ast
The HCMV gH/gL/UL128-131 compl ...... ization into target monocytes.
@en
The HCMV gH/gL/UL128-131 compl ...... ization into target monocytes.
@nl
type
label
The HCMV gH/gL/UL128-131 compl ...... ization into target monocytes.
@ast
The HCMV gH/gL/UL128-131 compl ...... ization into target monocytes.
@en
The HCMV gH/gL/UL128-131 compl ...... ization into target monocytes.
@nl
prefLabel
The HCMV gH/gL/UL128-131 compl ...... ization into target monocytes.
@ast
The HCMV gH/gL/UL128-131 compl ...... ization into target monocytes.
@en
The HCMV gH/gL/UL128-131 compl ...... ization into target monocytes.
@nl
P2093
P2860
P1433
P1476
The HCMV gH/gL/UL128-131 compl ...... ization into target monocytes.
@en
P2093
Andrew D Yurochko
Donna K Collins-McMillen
Emily V Stevenson
Gary C T Chan
Maciej T Nogalski
P2860
P304
P356
10.1371/JOURNAL.PPAT.1003463
P577
2013-07-11T00:00:00Z