Modification of tRNA(Lys) UUU by elongator is essential for efficient translation of stress mRNAs. - Test2 - elhamkhani - TriplyDB

Modification of tRNA(Lys) UUU by elongator is essential for efficient translation of stress mRNAs.

Modification of tRNA(Lys) UUU by elongator is essential for efficient translation of stress mRNAs.

http://www.wikidata.org/entity/Q34846015

about

Nucleoside modifications in the regulation of gene expression: focus on tRNA Biosynthesis and functions of sulfur modifications in tRNA Modification of the wobble uridine in bacterial and mitochondrial tRNAs reading NNA/NNG triplets of 2-codon boxes Yeast Kre33 and human NAT10 are conserved 18S rRNA cytosine acetyltransferases that modify tRNAs assisted by the adaptor Tan1/THUMPD1 Defects in tRNA Anticodon Loop 2'-O-Methylation Are Implicated in Nonsyndromic X-Linked Intellectual Disability due to Mutations in FTSJ1 Conservation of an intricate circuit for crucial modifications of the tRNAPhe anticodon loop in eukaryotes Different types of secondary information in the genetic code.tRNA thiolation links translation to stress responses in Saccharomyces cerevisiae.Rectifier of aberrant mRNA splicing recovers tRNA modification in familial dysautonomia Elongator and its epigenetic role in plant development and responses to abiotic and biotic stresses.Chemical genomics approach to identify genes associated with sensitivity to rapamycin in the fission yeast Schizosaccharomyces pombe.Genomic profiling of fungal cell wall-interfering compounds: identification of a common gene signature.Why Are tRNAs Overproduced in the Absence of Maf1, a Negative Regulator of RNAP III, Not Fully Functional?A functional genome-wide genetic screening identifies new pathways controlling the G1/S transcriptional wave.Distribution of ADAT-Dependent Codons in the Human Transcriptome A Comprehensive tRNA Genomic Survey Unravels the Evolutionary History of tRNA Arrays in Prokaryotes.Elongator-dependent modification of cytoplasmic tRNALysUUU is required for mitochondrial function under stress conditions.Lack of tRNA-i6A modification causes mitochondrial-like metabolic deficiency in S. pombe by limiting activity of cytosolic tRNATyr, not mito-tRNA.Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer Human cells have a limited set of tRNA anticodon loop substrates of the tRNA isopentenyltransferase TRIT1 tumor suppressor.Factors That Shape Eukaryotic tRNAomes: Processing, Modification and Anticodon-Codon Use.Elongator, a conserved complex required for wobble uridine modifications in eukaryotes.tRNA wobble modifications and protein homeostasis.An evolutionary approach uncovers a diverse response of tRNA 2-thiolation to elevated temperatures in yeast.Wobble uridine modifications-a reason to live, a reason to die?!Loss of ncm5 and mcm5 wobble uridine side chains results in an altered metabolic profile.Elp3 and Dph3 of Schizosaccharomyces pombe mediate cellular stress responses through tRNALysUUU modifications.Genome-wide Screening of Regulators of Catalase Expression: ROLE OF A TRANSCRIPTION COMPLEX AND HISTONE AND tRNA MODIFICATION COMPLEXES ON ADAPTATION TO STRESS.The emerging role of complex modifications of tRNA(Lys)UUU in signaling pathways Binding of the transcription factor Atf1 to promoters serves as a barrier to phase nucleosome arrays and avoid cryptic transcription.Deciphering the role of the signal- and Sty1 kinase-dependent phosphorylation of the stress-responsive transcription factor Atf1 on gene activation.A mutated dph3 gene causes sensitivity of Schizosaccharomyces pombe cells to cytotoxic agents.A genome-wide screen for FTY720-sensitive mutants reveals genes required for ROS homeostasis.TRMT1-Catalyzed tRNA Modifications Are Required for Redox Homeostasis To Ensure Proper Cellular Proliferation and Oxidative Stress Survival.Elp3 and RlmN: A tale of two mitochondrial tail-anchored radical SAM enzymes in Toxoplasma gondii.Codon optimality, bias and usage in translation and mRNA decay.Structural asymmetry in the eukaryotic Elongator complex.The Profile and Dynamics of RNA Modifications in Animals.mRNA Translation Gone Awry: Translation Fidelity and Neurological Disease.Monitoring the 5-methoxycarbonylmethyl-2-thiouridine (mcm5s2U) modification in eukaryotic tRNAs via the gamma-toxin endonuclease.

P2860

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P2860

Modification of tRNA(Lys) UUU by elongator is essential for efficient translation of stress mRNAs.

http://www.wikidata.org/entity/Q34846015

description

2013 nî lūn-bûn

@nan

2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年論文

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2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

Modification of tRNA

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Modification of tRNA(Lys) UUU ...... t translation of stress mRNAs.

@ast

Modification of tRNA(Lys) UUU ...... t translation of stress mRNAs.

@en

type

label

Modification of tRNA

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Modification of tRNA(Lys) UUU ...... t translation of stress mRNAs.

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Modification of tRNA(Lys) UUU ...... t translation of stress mRNAs.

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prefLabel

Modification of tRNA

@nl

Modification of tRNA(Lys) UUU ...... t translation of stress mRNAs.

@ast

Modification of tRNA(Lys) UUU ...... t translation of stress mRNAs.

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JOURNAL.PGEN.1003647

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Modification of tRNA(Lys) UUU ...... nt translation of stress mRNAs

@en

P2093

Damien Hermand

http://www.w3.org/2001/XMLSchema#string

Elena Hidalgo

http://www.w3.org/2001/XMLSchema#string

Itzel Vargas-Pérez

http://www.w3.org/2001/XMLSchema#string

Jorge Fernández-Vázquez

http://www.w3.org/2001/XMLSchema#string

Karin Buhne

http://www.w3.org/2001/XMLSchema#string

Mercè Carmona

http://www.w3.org/2001/XMLSchema#string

P2860

A functional proteomics approach links the ubiquitin-related modifier Urm1 to a tRNA modification pathway

Elongator is a histone H3 and H4 acetyltransferase important for normal histone acetylation levels in vivo.

Improvement of reading frame maintenance is a common function for several tRNA modifications.

Nuclear roles and regulation of chromatin structure by the stress-dependent MAP kinase Sty1 of Schizosaccharomyces pombe

Defects in tRNA modification associated with neurological and developmental dysfunctions in Caenorhabditis elegans elongator mutants

An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans

Ubiquitin-related modifier Urm1 acts as a sulphur carrier in thiolation of eukaryotic transfer RNA.

A primordial tRNA modification required for the evolution of life?

Thio-modification of yeast cytosolic tRNA requires a ubiquitin-related system that resembles bacterial sulfur transfer systems.

Elevated levels of two tRNA species bypass the requirement for elongator complex in transcription and exocytosis.

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e1003647

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scholarly article

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10.1371/JOURNAL.PGEN.1003647

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7

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P478

9

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P50

Sebastian A. Leidel

Miguel A Rodriguez-Gabriel

P577

2013-07-18T00:00:00Z

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250925523

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23874237

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3715433

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