A loss of function allele for murine Staufen1 leads to impairment of dendritic Staufen1-RNP delivery and dendritic spine morphogenesis. - Test2 - elhamkhani - TriplyDB

A loss of function allele for murine Staufen1 leads to impairment of dendritic Staufen1-RNP delivery and dendritic spine morphogenesis.

A loss of function allele for murine Staufen1 leads to impairment of dendritic Staufen1-RNP delivery and dendritic spine morphogenesis.

http://www.wikidata.org/entity/Q34856824

about

Mutations in the RNA granule component TDRD7 cause cataract and glaucoma Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt Neuronal RNA-binding proteins in health and disease The function of RNA-binding proteins at the synapse: implications for neurodegeneration Growth cone MKK7 mRNA targeting regulates MAP1b-dependent microtubule bundling to control neurite elongation Understanding neuronal connectivity through the post-transcriptional toolkit.Identification and dynamic changes of RNAs isolated from RALY-containing ribonucleoprotein complexes.Branching out: mechanisms of dendritic arborization.Molecular motors: directing traffic during RNA localization Mechanisms of dendritic mRNA transport and its role in synaptic tagging.Conserved RNA-binding proteins required for dendrite morphogenesis in Caenorhabditis elegans sensory neurons.Human Staufen1 associates to miRNAs involved in neuronal cell differentiation and is required for correct dendritic formation Smaug1 mRNA-silencing foci respond to NMDA and modulate synapse formation.Nxf7 deficiency impairs social exploration and spatio-cognitive abilities as well as hippocampal synaptic plasticity in mice.hnRNP Q regulates Cdc42-mediated neuronal morphogenesis.Principles and roles of mRNA localization in animal development Genomic analysis of RNA localization.Staufen2 functions in Staufen1-mediated mRNA decay by binding to itself and its paralog and promoting UPF1 helicase but not ATPase activity.Staufen1 impairs stress granule formation in skeletal muscle cells from myotonic dystrophy type 1 patients.Gene expression networks: competing mRNA decay pathways in mammalian cells.The Drosophila transcription factor Adf-1 (nalyot) regulates dendrite growth by controlling FasII and Staufen expression downstream of CaMKII and neural activity.Genome-wide analysis of Staufen-associated mRNAs identifies secondary structures that confer target specificity Cell-intrinsic drivers of dendrite morphogenesis.Increased axonal ribosome numbers is an early event in the pathogenesis of amyotrophic lateral sclerosis.RNA localization in neurite morphogenesis and synaptic regulation: current evidence and novel approaches.Mechanisms of translational regulation in synaptic plasticity.RNA granules: the good, the bad and the ugly.Integrating post-transcriptional regulation into the embryonic stem cell gene regulatory network.Staufen-mediated mRNA decay.The multifunctional Staufen proteins: conserved roles from neurogenesis to synaptic plasticity.Cell cycle-dependent regulation of the RNA-binding protein Staufen1.Agrin induces association of Chrna1 mRNA and nicotinic acetylcholine receptor in C2C12 myotubes.Mechanisms regulating dendritic arbor patterning.Multimerization of Staufen1 in live cells.Staufen1 senses overall transcript secondary structure to regulate translation mRNA binding protein staufen 1-dependent regulation of pyramidal cell spine morphology via NMDA receptor-mediated synaptic plasticity.Intra-axonal translation of SMAD1/5/8 mediates retrograde regulation of trigeminal ganglia subtype specification.Mammalian Staufen 1 is recruited to stress granules and impairs their assembly.Staufen targets coracle mRNA to Drosophila neuromuscular junctions and regulates GluRIIA synaptic accumulation and bouton number.The RNA-binding protein Staufen1 impairs myogenic differentiation via a c-myc-dependent mechanism.

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P2860

A loss of function allele for murine Staufen1 leads to impairment of dendritic Staufen1-RNP delivery and dendritic spine morphogenesis.

http://www.wikidata.org/entity/Q34856824

description

2008 nî lūn-bûn

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2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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A loss of function allele for ...... dendritic spine morphogenesis.

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A loss of function allele for ...... dendritic spine morphogenesis.

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A loss of function allele for ...... dendritic spine morphogenesis.

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A loss of function allele for ...... dendritic spine morphogenesis.

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A loss of function allele for ...... dendritic spine morphogenesis.

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A loss of function allele for ...... dendritic spine morphogenesis.

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A loss of function allele for ...... dendritic spine morphogenesis.

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A loss of function allele for ...... dendritic spine morphogenesis.

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Proceedings of the National Academy of Sciences of the United States of America

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A loss of function allele for ...... dendritic spine morphogenesis.

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Fabian Tübing

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Georgia Vendra

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Joel M Stein

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John P Vessey

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Julia Riefler

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Kelvin N Hawker

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Krzysztof Wieczorek

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Martin Mikl

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Michael A Kiebler

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Paolo Macchi

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P2860

Mammalian staufen is a double-stranded-RNA- and tubulin-binding protein which localizes to the rough endoplasmic reticulum

Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay

RNA recognition by a Staufen double-stranded RNA-binding domain

The brain-specific double-stranded RNA-binding protein Staufen2 is required for dendritic spine morphogenesis

Staufen, a gene required to localize maternal RNAs in the Drosophila egg.

Germline autonomy of maternal-effect mutations altering the embryonic body pattern of Drosophila.

Role of a neuronal small non-messenger RNA: behavioural alterations in BC1 RNA-deleted mice.

Dendritic protein synthesis, synaptic plasticity, and memory.

Isolation and characterization of Staufen-containing ribonucleoprotein particles from rat brain.

Staufen1 regulates diverse classes of mammalian transcripts.

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