Impaired clearance of apoptotic cardiocytes is linked to anti-SSA/Ro and -SSB/La antibodies in the pathogenesis of congenital heart block. - Test2 - elhamkhani - TriplyDB

Impaired clearance of apoptotic cardiocytes is linked to anti-SSA/Ro and -SSB/La antibodies in the pathogenesis of congenital heart block.

Impaired clearance of apoptotic cardiocytes is linked to anti-SSA/Ro and -SSB/La antibodies in the pathogenesis of congenital heart block.

http://www.wikidata.org/entity/Q34945212

about

Apotopes and the biliary specificity of primary biliary cirrhosis Chemotherapy synergizes with radioimmunotherapy targeting La autoantigen in tumors Congenital heart block: identification of autoantibody binding site on the extracellular loop (domain I, S5-S6) of alpha(1D) L-type Ca channel.Biliary apotopes and anti-mitochondrial antibodies activate innate immune responses in primary biliary cirrhosis Role of calcium channels in congenital heart block Impaired clearance of early apoptotic cells mediated by inhibitory IgG antibodies in patients with primary Sjögren's syndrome.β2-glycoprotein I and protection from anti-SSA/Ro60-associated cardiac manifestations of neonatal lupus.Rescue and worsening of congenital heart block-associated electrocardiographic abnormalities in two transgenic mice.A novel role of endothelin-1 in linking Toll-like receptor 7-mediated inflammation to fibrosis in congenital heart block.Binding of anti-SSA antibodies to apoptotic fetal cardiocytes stimulates urokinase plasminogen activator (uPA)/uPA receptor-dependent activation of TGF-β and potentiates fibrosis.Evaluation of fetuses in a study of intravenous immunoglobulin as preventive therapy for congenital heart block: Results of a multicenter, prospective, open-label clinical trial.Is disturbed clearance of apoptotic keratinocytes responsible for UVB-induced inflammatory skin lesions in systemic lupus erythematosus?Overview of fetal arrhythmias.Anatomical and pathological findings in hearts from fetuses and infants with cardiac manifestations of neonatal lupus Analysis of Clinical Factors Associated with Retinal Morphological Changes in Patients with Primary Sjögren's Syndrome.Reactivity to the p305 Epitope of the α1G T-Type Calcium Channel and Autoimmune-Associated Congenital Heart Block Umbilical cord blood levels of maternal antibodies reactive with p200 and full-length Ro 52 in the assessment of risk for cardiac manifestations of neonatal lupus.Congenital heart block: evidence for a pathogenic role of maternal autoantibodies Endosomal Toll-like receptors in clinically overt and silent autoimmunity.The Ro60 autoantigen binds endogenous retroelements and regulates inflammatory gene expression.Cell damage and autoimmunity: a critical appraisal Clinical and pathological roles of Ro/SSA autoantibody system.Atrioventricular conduction delay in fetuses exposed to anti-SSA/Ro and anti-SSB/La antibodies: a magnetocardiography study Autoimmune associated congenital heart block: integration of clinical and research clues in the management of the maternal / foetal dyad at risk.Ro60-associated single-stranded RNA links inflammation with fetal cardiac fibrosis via ligation of TLRs: a novel pathway to autoimmune-associated heart block.Pregnancy outcomes in patients with autoimmune diseases and anti-Ro/SSA antibodies.Targeting downstream transcription factors and epigenetic modifications following Toll-like receptor 7/8 ligation to forestall tissue injury in anti-Ro60 associated heart block.Autoantibodies from mice exposed to Libby amphibole asbestos bind SSA/Ro52-enriched apoptotic blebs of murine macrophages Identification of candidate loci at 6p21 and 21q22 in a genome-wide association study of cardiac manifestations of neonatal lupus.Ro60 requires Y3 RNA for cell surface exposure and inflammation associated with cardiac manifestations of neonatal lupus The consequences of apoptosis in autoimmunity.Doppler fetal mechanical PR interval prolongation with positive maternal anti-RNP but negative SSA/Ro and SSB/La auto-antibodies.Role of the urokinase plasminogen activator receptor in mediating impaired efferocytosis of anti-SSA/Ro-bound apoptotic cardiocytes: Implications in the pathogenesis of congenital heart block.O death where is thy sting? Immunologic tolerance to apoptotic self.Progress in the pathogenesis and treatment of cardiac manifestations of neonatal lupus.Ro52 autoantibodies arise from self-reactive progenitors in a mother of a child with neonatal lupus.Innate and humoral recognition of the products of cell death: differential antigenicity and immunogenicity in lupus.Modulation of natural IgM autoantibodies to oxidative stress-related neo-epitopes on apoptotic cells in newborns of mothers with anti-Ro autoimmunity.When the levee doesn't break: a novel role of beta2-glycoprotein I to protect against congenital heart block.Genetic imprinting of autoantibody repertoires in systemic lupus erythematosus patients.

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Impaired clearance of apoptotic cardiocytes is linked to anti-SSA/Ro and -SSB/La antibodies in the pathogenesis of congenital heart block.

http://www.wikidata.org/entity/Q34945212

description

2006 nî lūn-bûn

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2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2006 թվականի օգոստոսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年论文

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name

Impaired clearance of apoptoti ...... sis of congenital heart block.

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Impaired clearance of apoptoti ...... sis of congenital heart block.

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Impaired clearance of apoptoti ...... sis of congenital heart block.

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type

label

Impaired clearance of apoptoti ...... sis of congenital heart block.

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Impaired clearance of apoptoti ...... sis of congenital heart block.

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Impaired clearance of apoptoti ...... sis of congenital heart block.

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prefLabel

Impaired clearance of apoptoti ...... sis of congenital heart block.

@ast

Impaired clearance of apoptoti ...... sis of congenital heart block.

@en

Impaired clearance of apoptoti ...... sis of congenital heart block.

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Journal of Clinical Investigation

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Impaired clearance of apoptoti ...... esis of congenital heart block

@en

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Marguerita O'Mahony

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Petra J Neufing

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Ping Zheng

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Robert M Clancy

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Tom P Gordon

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P2860

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

Phosphatidylserine receptor in chronic pancreatitis: evidence for a macrophage independent role

Caspases are activated in a branched protease cascade and control distinct downstream processes in Fas-induced apoptosis

mRNA and protein expression of SSA/Ro and SSB/La in human fetal cardiac myocytes cultured using a novel application of the Langendorff procedure

Identification of a factor that links apoptotic cells to phagocytes

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

A lupus-like syndrome develops in mice lacking the Ro 60-kDa protein, a major lupus autoantigen

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2413-2422

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10.1172/JCI27803

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9

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116

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Falk Nimmerjahn

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2006-08-10T00:00:00Z

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16906225

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apoptotic process

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1533875

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